NexGard COMBO Topical for Cats 5.6-16.5 lbs (Yellow Box)

Monthly topical protection against key feline parasites

Product Description

NexGard COMBO is a prescription topical solution for cats weighing 5.6–16.5 lbs. It provides broad-spectrum parasite protection by killing adult fleas and controlling certain ticks for one month, preventing heartworm disease, and treating and controlling common intestinal worms. The dose is applied to the skin on the neck using a single-use applicator once monthly, as directed.

Benefits

• Broad Coverage: Kills fleas, controls ticks, prevents heartworm, treats intestinal worms.
• Once-Monthly Dosing: Applies monthly for consistent parasite protection coverage.
• Topical Convenience: No tablets needed; simple spot-on administration.
• Weight-Specific Dose: Designed for cats in the 5.6–16.5 lb range.
• Multi-Ingredient Action: Combines three actives for internal and external control.

Variants

1. NexGard COMBO Topical for Cats 1.8-5.5 lbs
2. NexGard COMBO Topical for Cats 5.6-16.5 lbs

Ingredients

Active Ingredients

Esafoxolaner, Eprinomectin, Praziquantel

How to Use

Directions for Use

• Dosing Chart:6–16.5 lb. cats use 0.9 mL applicator; apply entire contents.
• Monthly Schedule: Apply topically once a month, as directed.
• Application Site: Apply on the neck between the skull base and the shoulder blades.
• Skin Placement: Part hair to skin and apply in one spot only.
• Hand Hygiene: Wash hands with soap and water after use.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Topical Only: Do not administer orally; ingestion may cause excessive salivation.
• Human Contact: Avoid contact with the application site for 4 hours or until dry.
• Neurologic Caution: Use cautiously in cats with seizures or neurologic disorders.
• Age/weight Limits: Not tested in kittens under 8 weeks or under 1.8 lbs.
• Breeding Status: Safety not fully evaluated in breeding, pregnancy, or lactating cats.

Shipping & Returns

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy. 

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What parasites does NexGard COMBO protect cats against?

Ans: NexGard COMBO is indicated to prevent heartworm disease and to treat and control roundworms, hookworms, and tapeworms. NexGard COMBO also kills adult fleas and is indicated for the treatment and prevention of flea infestations, as well as specific tick infestations, for a period of one month.

Q2: How often is NexGard COMBO applied for ongoing protection?

Ans: NexGard COMBO is applied topically once a month. Monthly dosing provides continuous protection against labeled parasites. It can be used year-round, based on regional parasite risk and veterinary guidance, particularly for heartworm prevention, where consistent monthly dosing is crucial.

Q3: Where exactly should the topical dose be applied to a cat?

Ans: Apply the full contents to the skin on the midline of the neck, between the base of the skull and the shoulder blades. Part the hair until skin is visible, then apply it in one spot on an area the cat cannot lick.

Q4:  What is the correct dose for cats weighing 5.6–16.5 lbs?

Ans: For cats weighing 5.6–16.5 lbs, use the 0.9 mL unit applicator and apply the entire contents topically in a single spot. Using the correct weight-range applicator helps ensure the intended minimum dosing of all active ingredients.

Q5: Can cats lick the application area after NexGard COMBO is applied?

Ans: Cats should not be able to lick the application site. Apply to the neck area where licking is minimized and prevent contact between pets until the site is dry. If licking occurs, oral exposure can lead to excessive salivation.

Q6: Are there warnings about neurologic side effects with NexGard COMBO?

Ans: Esafoxolaner is an isoxazoline, a class associated with neurologic adverse reactions such as tremors, ataxia, and seizures. Seizures have been reported even without prior history, so use caution in cats with seizure or neurologic disorders.

Q7:  Is NexGard COMBO approved for kittens?

Ans: NexGard COMBO is indicated for cats and kittens 8 weeks of age and older and weighing 1.8 lbs or greater. The product has not been tested in kittens younger than 8 weeks or weighing less than 1.8 lbs.

Q8: What should people do after applying the topical solution?

Ans: Avoid direct contact with the application site for 4 hours or until the area is visibly dry. Wash your hands with soap and water after application. The product may cause mild to moderate eye irritation, so avoid eye contact.

Q9: Does NexGard COMBO require a prescription?

Ans: Yes. NexGard COMBO is a prescription animal drug and should be used by or on the order of a licensed veterinarian. Veterinary direction helps ensure the correct weight-range product selection and appropriate parasite prevention strategy for the cat.

Q10: What should happen if a monthly dose is missed?

Ans: If a dose is missed and the 30-day interval between doses is exceeded, apply NexGard COMBO immediately and resume the monthly dosing schedule. Consistent monthly dosing is especially important when using NexGard COMBO for heartworm prevention.