Advantage II Flea Control for Large Dogs (21-55 lbs) Red Box

Comprehensive Flea Prevention and Treatment for Dogs

Product Description

Advantage II for large dogs provides fast, effective protection against fleas, flea larvae, flea eggs, and lice, and prevents re-infestation. It is waterproof and easy to apply, supporting healthy skin and coat while keeping your dog comfortable and flea-free for up to 30 days. It begins killing adult fleas within 12 hours and also helps treat and control chewing lice infestations effectively. 

Benefits

• Flea Protection: Provides effective flea control for dogs 21–55 pounds.
• Easy Application: Monthly topical treatment is simple to apply, making flea prevention stress-free for pet owners.
• Total Flea Control: Kills adult fleas, flea larvae, and flea eggs through direct contact quickly and effectively.
• Fast-Acting Formula: Begins killing fleas the same day and continues protecting your dog for 30 days.
• Waterproof & Fragrance-Free: Topical formula is waterproof after 24 hours and free from fragrances for added convenience.
• Vet-Recommended Solution: Trusted by veterinarians, it ensures simple, monthly protection against fleas without prescriptions or oral medications.

Variants

• Small Dogs: 3–10 lbs
• Medium Dogs: 11–20 lbs
• Large Dogs: 21–55 lbs
• Extra Large Dogs: Over 55 lbs

Ingredients

Active Ingredients

Imidacloprid and Pyriproxyfen. 

Composition Table 

How to Use

Directions for Use

• Opening the Tube: Ensure the tube is at the pouch’s bottom. Use scissors to cut across the pouch top carefully.
• Selecting the Correct Product: Choose the appropriate Advantage II formula based on your dog’s weight category before applying the treatment.
• Preparing for Application: Bathe your dog prior to application and ensure they remain dry for 24 hours afterward.
• Applying the Treatment for Small Dogs (3–10 lbs): Hold the tube upright, remove the cap, and apply the contents directly to the skin between the shoulder blades.
• Applying for Medium to Extra-Large Dogs (11–20, 21–55 lbs, and over 55): Part the fur in several spots along the back, applying evenly from the shoulder blades to the tail.
• After Application and Disposal: Discard the empty tube safely, and do not reuse it. Repeat treatment monthly or as the veterinarian recommends.

Additional Information

Precautions

• General Safety Warning: Keep product out of children’s reach. Use cautiously to prevent accidental swallowing or contact incidents.
• Avoid Human Exposure: Avoid contact with eyes, skin, or clothing. Wash thoroughly after handling and before eating food.
• Application on Puppies: Do not use on puppies younger than 7 weeks old or weighing less than recommended.
• Species Restriction: Use only on dogs. Never apply this product to cats or other household animals.
• Sensitive or Sick Dogs: Avoid use on debilitated, aged, pregnant, or nursing dogs unless directed by a veterinarian.
• Veterinary Consultation: If irritation, discomfort, or allergic reactions occur, consult a veterinarian immediately before further applications. 

Possible Side Effects

• Post-Application Monitoring: Monitor your dog closely after each application to identify any unusual reactions or signs of discomfort.
• Skin Irritation Signs: Side effects may include redness, scratching, or visible skin irritation following product application.
• Discomfort Symptoms: Watch for signs of general discomfort such as itching, restlessness, or mild skin sensitivity.
• Gastrointestinal Reactions: Some dogs may experience vomiting, diarrhea, or mild stomach upset after receiving the treatment.
• Severe Side Effects: If lethargy or other concerning reactions appear, discontinue use immediately and consult your veterinarian.
• Veterinary Contact Information: For professional guidance regarding adverse effects, contact your veterinarian or call 1-800-422-9874 immediately. 

Storage and Disposal Instructions

• Prevent Contamination: Do not contaminate water, food, or feed by improper product storage, disposal, or handling procedures.
• Pesticide Storage: Keep in a cool, dry area that is inaccessible to both children and household pets.
• Container Handling: Use only nonrefillable containers; do not attempt to reuse or refill after initial product use.
• Empty Container Disposal: Place empty containers in household trash or offer them for recycling when local facilities permit.
• Partly Filled Container Disposal: Call your local waste agency or 1-800-422-9874 for detailed disposal instructions and guidance.
• Product Disposal Warning: Never pour unused pesticide product into indoor or outdoor drains to prevent environmental contamination.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Frequently Asked Questions

Q1: What is Advantage II Complete Flea Protection for Large Dogs used for?

Ans: Advantage II Complete Flea Protection for Large Dogs is used to treat and prevent flea infestations on dogs weighing 21 to 55 lbs. The topical formula targets adult fleas and immature stages to support consistent monthly flea control.

Q2: How do the active ingredients in Advantage II for Large Dogs work?

Ans: Advantage II for Large Dogs contains imidacloprid and pyriproxyfen, which work together to kill adult fleas and disrupt flea development. This combination helps reduce flea populations and supports long-term control with regular monthly application.

Q3: How often should Advantage II Complete Flea Protection be applied?

Ans: Advantage II Complete Flea Protection for Large Dogs is typically applied once every month. Maintaining a consistent monthly schedule helps ensure continuous flea control and reduces the risk of reinfestation throughout the year.

Q4: How quickly can results be seen after application?

Ans: Many pet parents notice a decrease in flea activity within hours after applying Advantage II for Large Dogs. Continued improvement usually occurs over the next few days as the product works to control existing fleas and prevent new infestations.

Q5: Where should Advantage II for Large Dogs be applied?

Ans: Advantage II for Large Dogs should be applied directly to the skin by parting the hair along the back or at the base of the neck. Applying to the skin ensures proper absorption and helps prevent licking.

Q6: Is Advantage II safe for puppies?

Ans: Advantage II Complete Flea Protection for Large Dogs is safe for puppies that are at least 7 weeks old and weigh between 21 and 55 lbs. Using the correct weight-specific product is important for safety and effectiveness.

Q7: Can dogs swim or be bathed after applying Advantage II?

Ans: Dogs can be bathed or swim after the product has fully dried. Allowing adequate drying time after application helps ensure the treatment remains effective during routine water exposure.

Q8: What side effects may occur with Advantage II for Large Dogs?

Ans: Some dogs may experience mild side effects such as skin irritation, temporary digestive upset, or mild lethargy. These effects are usually short-lived, but a veterinarian should be consulted if symptoms continue.

Q9: Can Advantage II for Large Dogs be used on other pets?

Ans: Advantage II Complete Flea Protection for Large Dogs should only be used on dogs within the specified weight range. Cats and other pets require species-appropriate flea treatments for safe and effective protection.