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Clomicalm (Clomipramine) Tablets

$1.98

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Prescription Required

Elanco SKU: VC01-0506-1

Strength: 5-mg
Size: 1 tablet
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Clomicalm (Clomipramine Hydrochloride) Tablets for Dogs

Product Description

Clomicalm is a veterinary-prescribed tablet formulated specifically to help manage anxiety-related behaviors in dogs—particularly separation anxiety and obsessive-compulsive disorders. By balancing serotonin and other neurotransmitters in the brain, Clomicalm helps reduce undesirable behaviors (such as excessive barking, inappropriate urination, and destructive chewing) that can strain the human-animal bond. Unlike temporary “quick fixes,” Clomicalm provides a sustained approach to mental wellness that improves quality of life for both pet and owner.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE. Packaging may arrive in a HardyPaw Pharmacy vial.

Ingredients

Ingredient

Function / Note

Clomipramine Hydrochloride

The active, anxiety-reducing ingredient; tricyclic antidepressant

Secondary (inactive) ingredients

Lactose monohydrate, microcrystalline cellulose, corn starch, colloidal silicon dioxide, magnesium stearate

Dosage Instructions

Clomicalm must be given exactly as prescribed by your veterinarian. Overdoses can be highly toxic.

  • Administration: Give orally, with or without food, ideally with food to minimize stomach upset.

  • Frequency: Typically every 12 to 24 hours, as directed. Consistency is key for effective anxiety control.

  • Missed Dose: Offer as soon as remembered unless it’s nearly time for the next dose. Never give two doses at once.

Dosage Comparison Table (by Tablet Strength and Dog Weight)

Dog Weight (lbs)

Recommended Dose (mg/day)

Tablets per Dose, per Day

Tablet Strength(s)

2.75-5.5

5 mg

1 tablet daily

5 mg

5.6-10.9

10 mg

2 tablets daily

5 mg

11-22

20 mg

1 tablet daily

20 mg

22.1-44

40 mg

1 tablet daily

40 mg

44.1-88

80 mg

1 tablet daily

80 mg

88.1-176

160 mg

2 tablets daily

80 mg

Typical total daily dose: 2-4 mg/kg/day. May be administered as a single daily dose or divided into two doses (morning and evening), based on your vet’s instructions.

Precautions

  • Provide a thorough medical history to your veterinarian (especially for seizure disorders or allergies to tricyclic antidepressants).

  • Not for pregnant, nursing, or breeding dogs.

  • Do not use with MAO inhibitors or other antidepressants unless directed.

  • Periodic vet monitoring is recommended for ongoing therapy.

  • Abrupt stopping may cause withdrawal—always taper under veterinary guidance.

Storage

  • Store at controlled room temperature, 59-77°F (15-25°C), in a dry location.

  • Keep in original container, out of reach of pets and children.

Benefits

  • Clinically Proven: Reduces separation anxiety, compulsive chewing, barking, and inappropriate urination by balancing neurotransmitters.

  • Veterinarian Recommended: Widely trusted for mental health support in dogs.

  • Supports Training: Works best combined with positive behavioral therapy routines.

  • Long-Term Solution: Addresses the biological cause of anxiety, not just the symptoms.

  • Easy to Use: Small, palatable tablets can be given with or without food.

  • FDA Approved: High standards for safety and effectiveness.

Frequently Asked Questions

How does Clomicalm work?

It increases serotonin levels in the brain, acting as an antidepressant to reduce anxiety symptoms and unwanted behaviors.

How long until improvement is seen?

Most pet owners see improvement within 2-4 weeks with consistent use and training, though each dog varies.

Can Clomicalm be used with training?

Yes—combination with behavior modification and environmental changes is ideal for best results.

Can all dogs take Clomicalm?

Most breeds and ages can use Clomicalm with proper vet supervision. Always confirm suitability and dosage for your individual dog.

Is it safe for long-term use?

Yes, with regular veterinary check-ins to monitor response and side effects.

Possible side effects?

Lethargy, stomach upset, reduced appetite, dry mouth, constipation, changes in appetite, rare urinary retention or increased heart rate. Serious reactions such as seizures require immediate vet attention.

Can it be given with other medications or supplements?

Notify your vet of all drugs and supplements your dog takes to avoid dangerous interactions.

What if a dose is missed?

Give the missed dose as soon as you remember unless it’s almost time for the next one. Do not double up.

Is Clomicalm for cats?

No; use only in dogs unless specifically directed by your veterinarian.

Is Clomicalm used for issues other than separation anxiety?

Sometimes, yes. Your veterinarian may recommend it for other behavioral issues as clinically indicated.

How can I tell if it’s working?

Decreased barking, destruction, or inappropriate elimination, plus overall calmer behavior, are typical signs that Clomicalm is effective.