Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Powerful 3-in-1 Defense for Fleas, Worms & Heartworm
Product Description
Trifexis® Chewable Tablets provide broad-spectrum protection for dogs by killing fleas, preventing heartworm disease, and treating intestinal parasites. Formulated with spinosad and milbemycin oxime, it starts killing fleas within 30 minutes and ensures month-long coverage. These beef-flavored tablets are safe, easy to administer with food, and help keep your dog healthy, active, and parasite-free.
Benefits
- Fast-Acting Flea Kill: Begins killing fleas within 30 minutes of administration and achieves 100% elimination within 4 hours.
- Heartworm Prevention: Prevents deadly heartworm disease by eliminating immature heartworm larvae before they reach the bloodstream.
- Intestinal Parasite Control: Effectively treats and controls hookworms, roundworms, and whipworms in adult dogs and puppies.
- Long-Lasting Protection: Provides continuous 30-day protection against fleas, heartworms, and intestinal worms with one monthly dose.
- Convenient Chewable Tablet: Palatable, beef-flavored chewable makes administration simple and stress-free for both pets and owners.
- Vet-Approved Safety: Clinically tested and FDA-approved for dogs 8 weeks and older, weighing at least 5 pounds.
Variants
Trifexis® Chewable Tablets for Dogs are available in the following pack sizes:
- Trifexis® 1 Chewable Tablet
- Trifexis® 6 Chewable Tablets
- Trifexis® 12 Chewable Tablets
Ingredients
Composition Table
| Ingredient | Quantity (per lb body weight) |
| Spinosad | 13.5 mg/lb (≈ 30 mg/kg) |
| Milbemycin Oxime | 0.2 mg/lb (≈ 0.5 mg/kg) |
Other Ingredients
Artificial beef flavoring, microcrystalline cellulose, croscarmellose sodium, stearic acid, silicon dioxide.
How to Use
Recommended-Dosage Chart
| Dog Weight (lbs) | Spinosad per Tablet | Milbemycin Oxime per Tablet | Tablets per Dose |
| 5 – 10 | 140 mg | 2.3 mg | 1 tablet |
| 10.1 – 20 | 270 mg | 4.5 mg | 1 tablet |
| 20.1 – 40 | 560 mg | 9.3 mg | 1 tablet |
| 40.1 – 60 | 810 mg | 13.5 mg | 1 tablet |
| 60.1 – 120 | 1620 mg | 27 mg | 1 tablet |
| Over 120 | Use appropriate combination | Use appropriate combination | As advised by vet |
Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.
Dosage & Administration Instructions
- Monthly Use: Administer Trifexis once every month to maintain continuous protection against fleas, heartworms, and intestinal parasites.
- Give With Food: Always administer the chewable tablet with food to ensure maximum absorption and effectiveness of the active ingredients.
- Observe After Dosing: Monitor your dog for one hour post-dosing; if vomiting occurs within this time, redose with a full tablet.
- Missed Dose: If a monthly dose is missed, administer Trifexis immediately with food and resume the regular monthly schedule.
- Heartworm Prevention: Begin treatment within one month of first mosquito exposure and continue monthly through the end of mosquito season.
- Multiple Pets: Treat all dogs in the household to prevent reinfestation; use separate flea prevention for cats, if applicable.
Additional Information
Precautions
- Heartworm Testing: Dogs should be tested for existing heartworm infections before starting Trifexis to avoid adverse reactions during treatment.
- Use with Epilepsy: Administer cautiously in dogs with pre-existing epilepsy, as isolated cases of seizures have been reported.
- Breeding Animals: Safety has not been evaluated in breeding males; use in breeding females only under veterinary supervision.
- Concurrent Medications: Avoid combining with high doses of ivermectin, as serious reactions have been reported when used together.
- Puppy Sensitivity: Puppies under 14 weeks may experience higher rates of vomiting during early doses, typically improving with age.
- Minimum Weight: Only administer to dogs weighing at least 5 pounds and older than 8 weeks of age for safety assurance.
- Mosquito Exposure: Fewer than three doses after mosquito season may reduce heartworm protection; continuous monthly use is recommended.
Possible Side Effects
- Vomiting: The most frequently observed side effect, often mild and typically resolving without additional medical treatment.
- Itching & Redness: Some dogs may experience mild pruritus, redness, or skin irritation following administration.
- Lethargy: Temporary fatigue or decreased activity has been noted but usually resolves as the body adjusts to the medication.
- Diarrhea: Mild gastrointestinal upset, including loose stools, may occur in a small percentage of treated dogs.
- Decreased Appetite: Occasional reduction in food intake has been reported and is generally short-lived.
- Neurological Signs: Rarely, trembling, ataxia, or seizures have been reported, particularly in dogs predisposed to such conditions.
- Hypersalivation: Excess drooling may occur briefly and typically subsides without further intervention.
Storage Information
- Temperature Range: Store between 68°F and 77°F (20°C to 25°C) with permissible short-term variations between 59°F and 86°F (15°C to 30°C).
- Keep Dry: Maintain tablets in a dry environment and protect from moisture to preserve potency and flavor integrity.
- Original Packaging: Keep tablets in their original blister packs until use to prevent contamination and maintain identification.
- Child Safety: Store out of reach of children and pets to prevent accidental ingestion or misuse.
- Shelf Stability: Proper storage ensures Trifexis maintains its full efficacy throughout its labeled shelf life.
Shipping & Return
We offer ground, express, priority, and international delivery; see our shipping policy for details.
For return instructions or product concerns, please refer to our detailed refund policy.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Frequently Asked Questions
Q1: How quickly does Trifexis start killing fleas?
Ans: Trifexis begins killing fleas within 30 minutes of administration and achieves 100% flea elimination within four hours. Continued monthly use prevents future infestations by killing fleas before they can lay eggs.
Q2: Can Trifexis prevent heartworm disease in dogs?
Ans: Yes, Trifexis prevents heartworm disease by eliminating immature heartworm larvae before they reach the bloodstream. Monthly administration ensures ongoing protection, especially during mosquito season. Dogs should test negative for heartworms before starting treatment.
Q3: What should I do if my dog vomits after taking Trifexis?
Ans: If your dog vomits within one hour of administration, redose with a full tablet to maintain effectiveness. Always give Trifexis with food to improve absorption and reduce the chance of stomach upset.
Q4: Is Trifexis safe for puppies and small dogs?
Ans: Trifexis is safe for dogs and puppies eight weeks or older, weighing at least five pounds. Puppies under 14 weeks may experience mild vomiting initially, which generally improves with age and continued dosing.
Q5: Can I give Trifexis with other medications?
Ans: Consult your veterinarian before combining Trifexis with other treatments. Adverse reactions have been reported when spinosad (a component) is used with high doses of ivermectin. Always disclose all medications your pet takes.
