Semintra Oral Solution for Cats

SEMINTRA (telmisartan oral solution) is the first and only FDA-approved treatment for feline hypertension in an easy-to-give liquid formulation. SEMINTRA safely and quickly lowers blood pressure to a healthy level within 14 days.

Easy-to-Use Syringe

•    Flexible delivery of dose straight into the mouth or on top of food

•    Calibrated for accurate dosing

Safe for Long-Term Administration

•    Once daily dosing after 14 days

•    Safety demonstrated in multiple studies

Convenient Liquid Formulation

•    As demonstrated in a survey: 91.2% of cat owners prefer a liquid formulation

Best-positioned anti-hypertensive to deal with an activated renin-angiotensin-aldosterone-system (RAAS) 

Telmisartan, the active substance in SEMINTRA, is an angiotensin receptor blocker (ARB), a class of medication that modulates the renin-angiotensin-aldosterone system (RAAS) by selectively blocking the effects of the AT1 receptor that is primarily responsible for vasoconstriction. This targeted mode of action of SEMINTRA ensures that beneficial effects mediated by the AT2, and other receptors, are spared, unlike angiotensin-converting enzyme inhibitors (ACE-I) whose RAAS blocking action produces poor anti-hypertensive effect⁶. And, although also recognized as an anti-hypertensive, calcium channel blockers like amlodipine, may potentially activate the RAAS.

Recommended Dosage

Use as directed by your veterinarian. 

Once the bottle is opened, use the contents within six months.

The initial dose of SEMINTRA® (telmisartan oral solution) is 1.5 mg/kg (0.68 mg/lb) orally twice daily for 14 days, followed by 2 mg/kg (0.91 mg/lb) orally once daily. The dose may be reduced by 0.5 mg/kg (0.23 mg/lb) increments to a minimum of 0.5 mg/kg (0.23 mg/lb) orally once daily to manage SEMINTRA-induced hypotension.

SEMINTRA can be administered directly into the mouth, or next to or on top of a small amount of food. Do not mix into food. 

SEMINTRA should be administered using the dosing syringe provided in the package. The dosing syringe fits onto the bottle and has 0.1 mL incremental marks. The dose should be rounded to the nearest 0.1 mL. If the cat vomits within 30 minutes of dosing, the cat may be re-dosed.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.