NexGard PLUS Chews for Small Dogs 4-8 lbs (Orange Box)

Monthly All-In-One Parasite Protection Chew

Product Description

NexGard Plus Chews are monthly beef-flavored soft chewables for dogs 4-8 lbs that combine afoxolaner, moxidectin, and pyrantel. One chew kills fleas and ticks, prevents heartworm disease, and treats and controls roundworms and hookworms. Suitable for puppies 8 weeks and older weighing at least 4 lbs, it can be given easily with or without food.

Benefits

• Flea & Tick Kill: Kills adult fleas and controls ticks for one month.
• Heartworm Prevention: Prevents heartworm disease when given monthly.
• Deworming Action: Treats and controls hookworms and roundworms.
• Triple-active Formula: Afoxolaner, moxidectin, and pyrantel work together in one chew.
• Puppy-safe Start: Approved for dogs 8 weeks+ and ≥4 lbs.

Ingredients

Afoxolaner; Moxidectin; Pyrantel 

How to Use

Dosage & Administration Instructions

• Monthly Dosing: Give orally once every month, year-round.
• Weight Match: Use chew labeled for 4-8 lbs body weight.
• Chew Strength: 9.375 mg afoxolaner / 45 mcg moxidectin / 18.75 mg pyrantel per chew.
• Full Dose Only: Ensure the dog consumes the complete chew.
• Missed Dose: Give a chew promptly, then resume the monthly schedule.

Additional Information

Precautions

• Neurologic Caution: Isoxazolines may cause tremors, ataxia, or seizures.
• Seizure History: Use with caution in dogs with a history of seizures or neurological issues.
• Heartworm Testing: Test dogs for existing heartworm disease before starting treatment.
• Not Adulticide: NexGard Plus does not kill adult heartworms.
• Breeding Safety Unknown: Not evaluated in breeding, pregnant, or lactating dogs.

Shipping & Returns

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Frequently Asked Questions

Q1. What parasites does NexGard Plus protect against?

Ans:  NexGard Plus is indicated to kill adult fleas, control ticks for one month, prevent heartworm disease, and treat and control adult hookworms and roundworms. It covers common external and internal parasites in a single monthly chew.

Q2. What is the correct dose for a 4–8 lb dog?

Ans:  Dogs weighing 4-8 lbs should receive one chew monthly containing 9.375 mg afoxolaner, 45 mcg moxidectin, and 18.75 mg pyrantel (pamoate). Selecting the right weight-range chew ensures labeled minimum mg/kg dosing.

Q3. How often should NexGard Plus be given?

Ans:  Give NexGard Plus orally once every month. Consistent monthly dosing is required for continuous flea, tick, and intestinal parasite control, as well as for heartworm prevention, including at least six months after the last mosquito exposure.

Q4. When can puppies start NexGard Plus?

Ans:  NexGard Plus is approved for puppies 8 weeks of age and older that weigh at least 4 lbs. Starting at the labeled age and weight helps ensure safety and proper efficacy against fleas, ticks, and heartworm larvae.

Q5. Can NexGard Plus be given with food?

Ans:  Yes. NexGard Plus may be administered with or without food. The important part is that the whole chew is consumed, so the dog receives the complete labeled dose for parasite control and prevention.

Q6. What should I do if my dog misses a dose of medication?

Ans: If a dose is missed, administer one NexGard Plus chew as soon as possible and then continue with a monthly schedule. Keeping doses on time helps prevent gaps in heartworm prevention and flea/tick protection.

Q7. Is NexGard Plus safe for dogs with seizures?

Ans: Afoxolaner is an isoxazoline, and this class has been associated with rare neurological reactions, such as tremors or seizures. Use NexGard Plus cautiously in dogs with a history of seizures and monitor them after dosing.

Q8. Does NexGard Plus treat existing adult heartworms in dogs?

Ans:  No. NexGard Plus is not effective against adult Dirofilaria immitis. Dogs should be tested for heartworm infection before starting treatment, and infected dogs may require adulticide treatment as directed by a veterinarian.

Q9. How quickly does NexGard Plus start working on fleas?

Ans: The afoxolaner component begins killing fleas within hours and maintains high efficacy through the full month. This rapid kill helps stop flea feeding and reduces egg laying, supporting better household control.

Q10. Can NexGard Plus be used in pregnant or breeding dogs?

Ans: The safe use of NexGard Plus has not been evaluated in breeding, pregnant, or lactating dogs. If parasite protection is needed during these stages, a veterinarian should weigh risks and benefits and advise on alternatives.