Naxcel Sterile Powder – Multi-Species Antibiotic

Naxcel Sterile Powder is a broad-spectrum, rapidly acting antibiotic designed for use across multiple animal species, including cattle, swine, sheep, goats, and horses. The veterinary antibiotic comprises ceftiofur sodium that is used in the treatment of bacterial infections, including bovine respiratory disease (BRD), swine respiratory disease (SRD), and foot rot in cattle. Naxcel is very easy to mix and administer, which makes it very effective in treating cattle without causing milk discard in dairy cows and with a very short withdrawal time in other food-producing animals. It has earned the utmost respect among veterinarians for maintaining the health and production of livestock and companion animals.

Benefits:

• Broad-Spectrum Antibiotic – Cures respiratory infections, foot rot, and others in diverse species. Fast-Acting Formula – Acts timely to kill and destroy pathogenic bacteria. No Milk Discard for Dairy Cattle – Safe in lactating cows without affecting continued milk production. Short Meat Withdrawal Period – Encourages prudent use of antibiotics in food-producing animals. Easy-to-Mix & Administer – Convenient reconstitution for effective treatment upon proper dosing.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

How is Naxcel administered?

Naxcel is reconstituted with sterile diluent and administered by intramuscular (IM) or subcutaneous (SC) injection, depending on the animal species and condition treated. Always use according to veterinary instructions.

What are the conditions for the use of Naxcel?

Naxcel is usually used to treat bovine respiratory disease (BRD), swine respiratory disease (SRD), cattle foot rot, and other bacterial infections in horses and livestock.

Dosage & Administration:

Cattle:

Administer to cattle by intramuscular or subcutaneous injection at the dosage of 0.5 to 1.0 mg ceftiofur per pound (1.1 to 2.2 mg/kg) of body weight (1-2 mL reconstituted sterile solution per 100 lbs body weight). Treatment should be repeated at 24-hour intervals for a total of three consecutive days. Additional treatments may be given on days four and five for animals that do not show a satisfactory response (not recovered) after the initial three treatments. Selection of dosage (0.5 to 1.0 mg/lb) should be based on the practitioner’s judgment of the severity of the disease (i.e., for respiratory disease, the extent of elevated body temperature, depressed physical appearance, increased respiratory rate, coughing and/or loss of appetite; and for foot rot, the extent of swelling, lesion, and severity of lameness).

Swine:

Administer to swine by intramuscular injection at the dosage of 1.36 to 2.27 mg ceftiofur per pound (3.0 to 5.0 mg/kg) of body weight (1 mL of reconstituted sterile solution per 22 to 37 lbs body weight). Treatment should be repeated at 24-hour intervals for a total of three consecutive days.

Sheep:

Administer sheep by intramuscular injection at the dosage of 0.5 to 1.0 mg ceftiofur per pound (1.1 to 2.2 mg/kg) of body weight (1-2 mL reconstituted sterile solution per 100 lbs body weight). Treatment should be repeated at 24-hour intervals for a total of three consecutive days. Additional treatments may be given on days four and five for animals that do not show a satisfactory response (not recovered) after the initial three treatments. Selection of dosage (0.5 to 1.0 mg/lb) should be based on the practitioner’s judgment of the severity of the disease (i.e., the extent of elevated body temperature, depressed physical appearance, increased respiratory rate, coughing, and/or loss of appetite).

Goats:

Administer goats by intramuscular injection at the dosage of 0.5 to 1.0 mg ceftiofur per pound (1.1 to 2.2 mg/kg) of body weight (1-2 mL reconstituted sterile solution per 100 lbs body weight). Treatment should be repeated at 24-hour intervals for a total of three consecutive days. Additional treatments may be given on days four and five for animals that do not show a satisfactory response (not recovered) after the initial three treatments. Selection of dosage (0.5 to 1.0 mg/lb) should be based on the practitioner’s judgment of the severity of the disease (i.e., the extent of elevated body temperature, depressed physical appearance, increased respiratory rate, coughing, and/or loss of appetite). Pharmacokinetic data indicate that the elimination of the drug is more rapid in lactating. For lactating, the high end of the dose range is recommended.

Horses:

Administer to horses by intramuscular injection at the dosage of 1.0 to 2.0 mg ceftiofur per pound (2.2 to 4.4 mg/kg) of body weight (2-4 mL reconstituted sterile solution per 100 lbs body weight). A maximum of 10 mL may be administered per injection site. Treatment should be repeated at 24-hour intervals, continued for 48 hours after clinical signs have disappeared, and should not exceed 10 days.

Dogs:

Administer to dogs by subcutaneous injection at the dosage of 1.0 mg ceftiofur per pound (2.2 mg/kg) of body weight (0.1 mL reconstituted sterile solution per 5 lbs body weight). Treatment should be repeated at 24-hour intervals for 5-14 days.

Reconstituted NAXCEL Sterile Powder is to be administered to dogs by subcutaneous injection. No vial closure should be entered more than 20 times. Therefore, only the 1-gram vial is approved for use in dogs.

Da Old Chicks:

Administer by subcutaneous injection in the neck region of day-old chicks at the dosage of 0.08 to 0.20 mg ceftiofur/chick. One mL of the 50 mg/mL reconstituted solution will treat approximately 250 to 625-day-old chicks.

Reconstituted NAXCEL Sterile Powder is to be administered by subcutaneous injection only. A sterile 26 gauge needle and syringe or a properly cleaned automatic injection machine should be used.

Day Old Turkey Poults

Administer by subcutaneous injection in the neck region of day-old turkey poults at the dosage of 0.17 to 0.5 mg ceftiofur/poult. One mL of the 50 mg/mL reconstituted solution will treat approximately 100 to 294-day-old turkey poults.

Reconstituted NAXCEL Sterile Powder is to be administered by subcutaneous injection only.

Precautions:

The effects of ceftiofur on the reproductive performance, pregnancy, and lactation of cattle, swine, sheep, and goats have not been determined.

Cattle

Following subcutaneous administration of ceftiofur sodium in the neck of cattle, small areas of discoloration at the site may persist beyond five days, potentially resulting in trim loss of edible tissues at slaughter.

As with any parenteral injection, localized post-injection bacterial infections may result in abscess formation. Attention to hygienic procedures can minimize their occurrence.

Swine

The safety of ceftiofur has not been determined for swine intended for breeding.

Horses

The safety of ceftiofur has not been determined for horses intended for breeding. The administration of antimicrobials to horses under conditions of stress may be associated with acute diarrhea that could be fatal. If acute diarrhea is observed, discontinue the use of this antimicrobial and initiate appropriate therapy.

Dogs

The safety of ceftiofur has not been determined for dogs intended for breeding, or pregnant dogs.

Storage:

Store unreconstituted product at controlled room temperature 20° to 25° C (68° to 77° F).

Store reconstituted product either in a refrigerator at 2° to 8° C (36° to 46° F) for up to 7 days or at controlled room temperature 20° to 25° C (68° to 77° F) for up to 12 hours.

Protect from light. The color of the cake may vary from off-white to tan color. Color does not affect potency.

ONE-TIME SALVAGE PROCEDURE FOR RECONSTITUTED PRODUCT

At the end of the 7-day refrigeration or 12-hour room temperature storage period following reconstitution, any remaining reconstituted product may be frozen for up to 8 weeks without loss in potency or other chemical properties. This is a one-time-only salvage procedure for the remaining product. To use this salvaged product at any time during the 8-week storage period, hold the vial under warm running water, gently swirling the container to accelerate thawing, or allow the frozen material to thaw at room temperature. Rapid freezing or thawing may result in vial breakage. Any product not used immediately upon thawing should be discarded.

Shipping & Returns

• Shipping: Learn more about our flexible shipping options by visiting our Shipping Policies.
• Returns: For assistance with returns or replacements, review our Refund Policy.

FAQ

What is Naxcel applied for?

Naxcel is a cephalosporin, a broad-spectrum antibiotic utilized to treat respiratory and bacterial infections in various animals, including swine, cattle, horses, goats, and sheep.

What is the active ingredient in Naxcel?

The active component is Ceftiofur Sodium, a broad-spectrum powerful antibiotic.

What species are treated with Naxcel?

It is approved for use in cattle, swine, sheep, goats, horses, and even some avian species. Always consult a veterinarian for dosing by species.

Is Naxcel labeled for use in lactating dairy cows?

Yes, Naxcel is secure in lactating dairy cows with no withdrawal from milk when given as directed.

How long does Naxcel remain effective after reconstitution?

After reconstitution, Naxcel needs to be refrigerated and should be used within 7 days. Freeze-stored, Naxcel is usable for up to 8 weeks.

Does Naxcel cause side effects?

Some animals may experience a slight swelling at the site of injection. Adverse reactions are uncommon but recommend a veterinarian in case of any abnormal response.