Synchsure (Cloprostenol Sodium) Injection (100ml - 50 doses)

Estrus-Synchronizing Prostaglandin for Cattle Programs

Product Description

Synchsure is a sterile cloprostenol sodium injection (prostaglandin F2α analogue) for beef cows, lactating dairy cows, and replacement heifers. Given intramuscularly, it induces luteolysis to synchronize estrus, treat pyometra or chronic endometritis, resolve mummified fetus or luteal cysts, and terminate pregnancy from mismating. Cycling animals typically show estrus two to five days post-treatment.

Benefits

• Reproductive Control: Induces luteolysis to manage the estrous cycle precisely.
• Estrus Sync Aid: Supports single- or two-injection breeding programs.
• Condition Therapy: Treats pyometra/endometritis and related prolonged luteal conditions.
• Predictable Timing: Estrus usually occurs 2-5 days after injection.
• Room-temp Stable: No refrigeration required; six-month shelf life after opening.

Ingredients

Active ingredient: Cloprostenol 250 mcg/mL (equivalent to 263 mcg cloprostenol sodium/mL).
Inactive ingredients: Sodium citrate; Citric acid (anhydrous); Sodium chloride; Chlorocresol; Water for injection.

How to Use

Dosage & Administration Instructions

Benefits

• Reliable Estrus Sync: Induces luteolysis for consistent, predictable estrus timing in cattle.
• Fast-Acting Results: Cycling cattle typically show estrus about 2-5 days post-treatment.
• Reproductive Therapy: Treats pyometra/endometritis and helps restore normal cyclicity.
• Cost-Efficient Vial: 100 mL bottle provides 50 doses, supporting herd program economy.
• Easy Protocols: Fits single- or two-injection breeding programs with precise IM dosing.

Additional Information

Precautions

• Vet-Only Use: Federal law restricts use to a licensed veterinarian.
• Accidental Injection: Seek medical help immediately if self-injected.
• Room Storage: Store at controlled room temperature; protect from light.
• Discard Timeline: Discard unused product 180 days after first use.

Shipping & Returns

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Frequently Asked Questions

Q1. What is Synchsure used for in cattle?

Ans: Synchsure is used to induce luteolysis and manipulate the estrous cycle in beef and dairy cattle. It’s labeled for estrus synchronization, treating pyometra or chronic endometritis, resolving mummified fetuses or luteal cysts, and terminating mismated pregnancies.

Q2. How soon will cattle show estrus after Synchsure?

Ans: In normal cycling, nonpregnant cattle, estrus typically occurs about two to five days after a Synchsure injection. Timing can vary with herd management, stage of cycle, and health status, so observation and veterinary guidance remain essential.

Q3. What is the labeled Synchsure dose and route?

Ans: The labeled dose is 2 mL per animal, delivering 500 mcg cloprostenol, administered by intramuscular injection. Other routes should not give Synchsure, and aseptic technique is required to reduce injection-site complications.

Q4. Can Synchsure be used in timed AI programs?

Ans: Yes, Synchsure can be incorporated into controlled breeding programs, including protocols where it’s used with Cystorelin to synchronize estrus for fixed-time artificial insemination in lactating dairy cows and beef cows, per label-directed schedules.

Q5. Does Synchsure work in pregnant cattle?

Ans: Synchsure may cause abortion depending on the gestational stage because it induces regression of the corpus luteum. It is labeled for the termination of pregnancy due to mismating. Use only under veterinary supervision with clear reproductive management goals.

Q6. What reproductive conditions can Synchsure treat?

Ans: Synchsure is labeled to treat pyometra and chronic endometritis associated with prolonged luteal function. It also supports the resolution of mummified fetuses and luteal cysts by inducing luteolysis, allowing cows to return to normal cyclicity.

Q7. Are there special handling warnings for people?

Ans: Yes, Cloprostenol can be absorbed through the skin and may cause bronchospasm or miscarriage. Women of child-bearing age, pregnant women, and asthmatics should avoid contact. Accidental self-injection requires immediate medical attention.

Q8. How should Synchsure be stored once opened?

Ans: Synchsure does not require refrigeration. Store at controlled room temperature and protect from light. After first use, the bottle remains usable for six months, but any remaining product must be discarded 180 days after opening.

Q9. Can Synchsure be given in a single-injection program?

Ans: Yes, Synchsure may be used as a single injection program or as a two-dose program, depending on herd needs. Your veterinarian can choose the best protocol for observed estrus breeding or cleanup bull exposure afterward.

Q10. What animals is Synchsure approved for?

Ans: Synchsure is approved for beef cows, lactating dairy cows, and replacement beef and dairy heifers. It is not labeled for use in other species unless a veterinarian determines that extra-label use is appropriate under applicable regulations.