Zenrelia (ilunocitinib tablets) for Dogs, 15-mg

Targeted relief for itchy allergic dogs

Product Description

Zenrelia is a prescription tablet taken by mouth to help relieve itching and skin inflammation linked to allergies and atopic dermatitis in dogs. It works by blocking certain JAK pathways that trigger itch and inflammation. This helps provide fast, targeted relief while also supporting long-term comfort. Zenrelia is made for dogs 12 months of age and older and is given once a day.

Benefits

• Fast itch relief: Helps ease itching caused by allergies and atopic dermatitis, often improving comfort within the first few days.
• Targeted JAK action: Blocks the signals in the body that cause itching and inflammation in dogs.
• Once daily use: It is administered once daily and may be given with or without meals, making it simple to incorporate into a regular schedule.
• Supports chronic skin care: Shown in veterinary studies to lower itch levels and improve the look and feel of irritated skin.
• Designed for long-term management: Studied for safety and effectiveness during extended use to help control ongoing allergic skin conditions.

Variants

• 8 mg
• 4 mg
• 5 mg
• 15 mg

Ingredients

Active Ingredients

Ilunocitinib

How to Use

Recommended Dosage Chart

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Dosage and Administration Instructions

• Daily Dose: Administer once per day at a dosage of 0.27 to 0.36 mg per pound of body weight, based on the tablet strength prescribed for your dog.
• With or Without Food: The medication can be given alongside meals or on an empty stomach, allowing flexibility with your dog’s usual feeding schedule.
• Vaccination Timing: Discontinue Zenrelia at least 28 days prior to any vaccination and wait a minimum of 28 days after the vaccine before restarting treatment.
• Age requirement: Use only in dogs 12 months of age or older to ensure safe and appropriate treatment response.
• Monitor health: Monitor for signs of infection since Zenrelia can increase susceptibility to certain bacterial or viral illnesses.

Additional Information

Precautions

• Breeding, Pregnancy, and Nursing: The safety of this medication has not been established in pregnant, breeding, or nursing dogs. For that reason, it is not recommended for use in these animals.
• Use With Other Immunosuppressants: It has not been studied in combination with corticosteroids, cyclosporine, or other systemic immune suppressing drugs and should not be used alongside them.
• Immune System Considerations: Because the drug alters immune function, it may influence normal immune responses. Veterinary supervision is advised before starting treatment.
• Prostate Findings: Laboratory studies noted a reduction in prostate size in intact male dogs.

Possible Side Effects

• Digestive problems: Some dogs may have vomiting, diarrhea, loss of appetite, or an upset stomach during treatment, based on clinical study results.
• Low energy: A few dogs may seem more tired or less active, especially in the early stages of treatment.
• Breathing issues: Coughing, wheezing, and occasional respiratory infections were reported in some dogs during studies.
• Skin growths: Some dogs developed skin growths such as cysts or papillomas during clinical trials.
• Urinary issues: Urinary tract infections were noted in dogs taking Zenrelia and may need monitoring by a veterinarian.

Storage Information

• Room temperature: Store at 59 to 77 degrees Fahrenheit with permitted short-term excursions between 41 and 104 degrees Fahrenheit.
• Keep secure: Store in a locked or inaccessible area to prevent accidental ingestion by pets or children.
• Original packaging: Keep tablets in their original blister or bottle packaging to maintain product stability and ensure correct dosing.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: How does Zenrelia help reduce itching in dogs?

Ans: Zenrelia works by blocking specific JAK(Janus kinase) dependent cytokines that trigger itching and inflammation in allergic and atopic dermatitis. This targeted action helps reduce itch intensity and improve skin comfort in affected dogs when used as prescribed by a veterinarian.

Q2: How fast does Zenrelia start relieving my dog’s itching?

Ans: Clinical studies show that dogs receiving Zenrelia experience noticeable reductions in itching within the first several days of treatment. Improvement continues with daily use, and most dogs demonstrate meaningful itch reduction by Day 7 of therapy.

Q3: Can Zenrelia be given with food or on an empty stomach?

Ans: Zenrelia can be administered with or without food, allowing flexibility according to your dog’s routine. Although absorption increases with food, the manufacturer states that either method is acceptable for daily dosing when following prescribed instructions.

Q4: Can my dog receive vaccines while taking Zenrelia?

Ans: Dogs should not receive vaccines while taking Zenrelia because it may reduce vaccine effectiveness. The manufacturer advises stopping Zenrelia 28 days to 3 months before any vaccination and withholding it for at least 28 days after vaccination.

Q5: Is Zenrelia safe for all dogs?

Ans: Zenrelia is only approved for dogs 12 months of age or older. It should not be used in dogs with serious infections or those that are pregnant, breeding, or lactating. Veterinary supervision is required to ensure safe and appropriate use.