Antisedan (atipamezole hydrochloride) 10ml (5mg/ml)

Fast Sedation Reversal for Dogs 

Product Description

Antisedan is an injectable drug for dogs that is used to counteract the sedative and pain-relieving effects of Dexdomitor and Dexdomitor 0.1. It contains atipamezole hydrochloride, an alpha2 adrenergic antagonist that works by blocking the action of dexmedetomidine. When given intramuscularly, Antisedan promotes a fast and reliable recovery, with most dogs becoming alert and mobile within five to ten minutes following administration. 

Benefits

·         Fast Sedation Reversal: Quickly counteracts the sedative and pain-relieving effects of Dexdomitor and Dexdomitor 0.1 in dogs.

·         Quicker Return to Awareness: Helps dogs regain consciousness and normal movement within minutes after intramuscular administration.

·         Shorter Sedation Duration: Reduces the length of time dogs remain non-ambulatory following veterinary diagnostic or surgical procedures.

·         Streamlined Clinical Workflow: Allows for faster patient discharge and improved efficiency for veterinary teams and clinic staff.

·         Consistent Reversal Mechanism: Delivers dependable results by selectively blocking alpha2 adrenergic receptors in dogs.

Variants

Antisedan Injectable Solution 5 mg per mL 

Ingredients

Active Ingredients

Atipamezole hydrochloride

Inactive Ingredients

Methylparaben, sodium chloride, water for injection

How to Use

Dosage & Administration Instructions

The following dosage information is based solely on FDA-approved manufacturer labeling and is intended for informational purposes only.

·         Prescription Status: Antisedan is labeled for use in dogs only by or on the order of a licensed veterinarian.

·         Approved Indication: Antisedan is approved for use in dogs to reverse the sedative and pain-relieving effects caused by dexmedetomidine.

·         Labeled Route: Product labeling states that Antisedan is intended for intramuscular injection in canine patients.

·         Dose Relationship: The recommended dose volume is typically the same as the dose volume previously given for Dexdomitor.

·         Recovery Timing: Reversal of sedation usually takes place within five to ten minutes when used as directed.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

·         Health Conditions: Use is not advised in dogs with heart, lung, liver, or kidney disorders.

·         Stress States: Labeling recommends caution when used in dogs affected by shock, severe weakness, or extreme environmental stress.

·         Age Limitations: Safety has not been assessed in dogs younger than four months of age or those with very low body weight.

·         Breeding Status: Antisedan has not been studied for use in breeding dogs or in dogs that are pregnant or nursing.

Possible Side Effects

·         Vomiting Reactions: Manufacturer safety data reports that vomiting may occur occasionally after use.

·         Behavioral Responses: During sedation recovery, some dogs may briefly exhibit signs of excitement or apprehension.

·         Gastrointestinal Reactions: Digestive reactions reported after labeled use may include hypersalivation or diarrhea in some dogs.

·         Muscle Related Effects: Infrequent cases of tremors have been reported and are typically short-lasting according to safety assessments.

Storage Information

·         Storage Temperature: Store the product at a controlled room temperature of 20°C to 25°C as stated in the labeling.

·         Allowed Temperature Range: Brief storage between 15°C and 30°C is permitted under manufacturer guidance.

·         Original Packaging: Keep the medication in its original container until use to protect sterility and product integrity.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy. 

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.  

Frequently Asked Questions

Q1: What is Antisedan used for in dogs?

Ans: Antisedan is approved for use in dogs to reverse the sedative and pain-relieving effects of Dexdomitor and Dexdomitor 0.1 after veterinary procedures. It works by blocking alpha2 adrenergic receptors, helping dogs regain alertness and movement more quickly.

Q2: How quickly does Antisedan work after use?

Ans: Based on manufacturer labeling, Antisedan generally provides dependable sedation reversal within five to ten minutes when given intramuscularly to dogs. While recovery speed can vary by individual, a rapid return to awareness and mobility is commonly seen.

Q3: Is Antisedan safe for all dogs?

Ans: Antisedan is not advised for dogs with heart, lung, liver, or kidney conditions, or for dogs experiencing shock or extreme stress. According to FDA labeling, safety has not been established in very young dogs, breeding animals, or dogs that are pregnant or nursing.

Q4: Does Antisedan require a prescription?

Ans: Yes, Antisedan is available only by prescription. FDA-approved labeling specifies that it must be administered by or under the direction of a licensed veterinarian to ensure proper medical supervision during sedation reversal.