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Simparica Trio for Dogs (Sarolaner, Moxidectin, and Pyrantel) 44.1-88 lbs - Complete Protection

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$62.00

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Zoetis SKU: 10022670

5.0 / 5.0 based on 1 review
Size: 1 Chewable Tablet

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Simparica Trio for Dogs 44.1-88 lbs

3-in-1 Protection Against Fleas, Ticks & Heartworms

Simparica Trio for Dogs 44.1-88 lbs is a once-monthly chewable tablet that provides triple protection against fleas, ticks, and heartworm disease, while also treating roundworms and hookworms. Manufactured by Zoetis, this FDA-approved medication delivers fast-acting, broad-spectrum parasite defense in a single, liver-flavored chew that dogs love.

Designed for medium to large dogs (44.1-88 lbs), Simparica Trio offers a simple and convenient way to keep your pet protected year-round from harmful parasites that can cause serious health issues.

Also Available In:

Simparica Trio is available in different dosage strengths to ensure optimal protection for dogs of all sizes. Find the perfect dose for your furry friend:

Simparica Trio Chewable Tablets for Puppies 2.8-5.5 lbs
Simparica Trio Chewable Tablets for Dogs 5.6-11.0 lbs
Simparica Trio Chewable Tablets for Dogs 11.1-22.0 lbs
Simparica Trio Chewable Tablets for Dogs 22.1-44.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 88.1-132.0 lbs

Ensure your dog gets the right dosage for their size and weight to receive full-spectrum parasite protection. 🐶💙

Why Choose Simparica Trio for Dogs 44.1-88 lbs?

 All-in-One Parasite Protection – Eliminates fleas and ticks, prevents heartworm disease, and treats roundworms and hookworms.
 Fast-Acting & Long-Lasting – Kills fleas within 4 hours and ticks within 8 hours with 30-day continuous protection.
 Easy, Tasty Chewable – No messy topicals or difficult pills—just a delicious liver-flavored chew.
 Vet-Recommended & FDA-Approved – Trusted by veterinarians to provide safe and effective parasite control.

Proven Effectiveness

Parasite Effectiveness
Fleas 100% efficacy within 8 hours
Ticks (5 species) 98.9% efficacy
Roundworms 99.2% efficacy
Hookworms 94% efficacy

How Does Simparica Trio for Dogs 44.1-88 lbs Work?

Simparica Trio contains three powerful active ingredients that target multiple parasites:

  • Sarolaner – An isoxazoline-class compound that rapidly kills fleas before they lay eggs and eliminates 5 species of disease-carrying ticks.
  • Moxidectin – Prevents heartworm disease by eliminating larval-stage heartworms transmitted by mosquitoes.
  • Pyrantel Pamoate – Treats and controls roundworms and hookworms, reducing the risk of intestinal infections.

Unlike spot-on treatments, Simparica Trio provides full-body protection with just one chew per month.

How to Use Simparica Trio for Dogs 44.1-88 lbs? (Dosage & Administration)

Dosage Guidelines

Dog Weight (lbs) Sarolaner (mg) Moxidectin (mg) Pyrantel (mg) Tablets Per Month
44.1 – 88.0 lbs 48 mg 0.96 mg 200 mg 1 tablet
  • Administer once a month, every month to ensure continuous protection.
  • Can be given with or without food.
  • If a dose is missed, administer it immediately and resume the regular monthly schedule.

Why Use Simparica Trio Year-Round?

Heartworm Prevention

  • Prevents heartworm disease caused by Dirofilaria immitis, which is transmitted by mosquitoes.
  • Dogs should be tested for heartworm infection before starting treatment.

Flea Control & Prevention

  • Kills adult fleas before they can lay eggs, stopping infestations.
  • Starts working within 4 hours and provides continuous flea protection for 30 days.

Tick Treatment & Prevention

  • Eliminates Lone Star ticks, Gulf Coast ticks, American dog ticks, Black-legged ticks (deer ticks), and Brown dog ticks.
  • Kills ticks within 8 hours to prevent disease transmission.

Roundworm & Hookworm Treatment

  • Treats and controls Toxocara canis, Toxascaris leonina, Ancylostoma caninum, and Uncinaria stenocephala.
  • Helps prevent digestive issues and nutrient deficiencies caused by intestinal parasites.

Is Simparica Trio Safe? (Side Effects & Warnings)

Simparica Trio is safe for dogs 8 weeks and older, weighing at least 2.8 lbs. However, some dogs may experience mild side effects.

Possible Side Effects:

  • Vomiting
  • Diarrhea
  • Lethargy
  • Decreased appetite
  • Increased thirst or urination
  • Muscle tremors (rare)

Warnings & Precautions:

 Use with caution in dogs with a history of seizures or neurological disorders.
 Not evaluated for use in breeding, pregnant, or lactating dogs.
 Keep out of reach of children and pets to prevent accidental overdose.

Shipping & Returns 

  • Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.
  • Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Frequently Asked Questions (FAQs)

1. What is Simparica Trio for Dogs 44.1-88 lbs used for?

Simparica Trio is a monthly chewable tablet that prevents heartworm disease, kills fleas and ticks, and treats roundworms and hookworms in dogs weighing 44.1-88 lbs.

2. How quickly does Simparica Trio start working?

Simparica Trio begins killing fleas within 4 hours and ticks within 8 hours after administration.

3. Can I give Simparica Trio with food?

Yes! Simparica Trio can be given with or without food, and most dogs enjoy its liver-flavored taste.

4. Does Simparica Trio help prevent Lyme disease?

Yes! By killing deer ticks (Ixodes scapularis), Simparica Trio helps reduce the risk of Lyme disease transmission.

5. What if I miss a dose of Simparica Trio?

If you miss a dose, administer it immediately, then resume the regular monthly schedule. If unsure, consult your veterinarian.

Customer Reviews

Based on 1 review
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C
Corinne Barde
Perfect all the way

Great product, awesome communication &customer service. Highly recommend 👍🏻👍🏻