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Vetoryl Capsules (Trilostane) for Dogs - 10mg

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£67.00

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Dechra SKU: VETO-1030 Barcode: 317033110300

Size: 30 Capsules

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Vetoryl 10mg Trilostane Capsules for Dogs

Cushing’s Disease Management

Vetoryl 10mg Trilostane Capsules for Dogs is a prescription medication designed to manage hyperadrenocorticism (Cushing’s disease) in canines. The active ingredient, Trilostane, works by inhibiting the production of excess cortisol—a hormone responsible for Cushing's symptoms like increased thirst, panting, and abdominal bloating.

This FDA-approved treatment is primarily used to regulate pituitary-dependent and adrenal-dependent Cushing’s syndrome, offering a safer, more controlled solution for dogs suffering from hormonal imbalances. Vetoryl is suitable for long-term therapy and supports better quality of life for your pet.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Save time and money with our AutoShip option—get Vetoryl 10mg capsules for dogs delivered on schedule with extra discounts on every order!

Also Available in Other Vetoryl Strengths for Dogs

To ensure accurate and safe dosing based on your dog’s weight and condition, HardyPaw offers Vetoryl in multiple strengths. Choose the right option as prescribed by your veterinarian:

📌 Always follow your vet’s dosing recommendation and adjust strength as needed based on follow-up testing and response.

What Are the Benefits of Vetoryl 10mg Trilostane Capsules for Dogs?

Vetoryl provides a clinically proven approach to managing canine endocrine disorders:

  • Effective cortisol control: Trilostane reduces excessive cortisol production, easing symptoms of Cushing’s disease.
  • Improves quality of life: Helps reduce lethargy, pot-bellied appearance, and skin issues associated with the disease.
  • Dual action treatment: Works for both pituitary and adrenal forms of Cushing’s.
  • FDA-approved for veterinary use, ensuring safety and reliability.
  • Precision-dosed capsules: Easy to administer and available in multiple strengths to suit your dog’s size and condition.

Understanding Cushing’s Disease in Dogs

Cushing’s disease is caused by excess production of cortisol, a steroid hormone. It affects middle-aged to older dogs and presents with:

  • Frequent urination
  • Increased appetite and thirst
  • Pot-bellied appearance
  • Hair thinning or patchy coat
  • Lethargy and weight gain

Without treatment, it can lead to complications like diabetes, hypertension, or kidney failure.

How Should Vetoryl 10mg Be Administered to Dogs? (Dosage and Administration)

  • Always consult your veterinary for exact dosage instructions depending on your pet's condition.
  • Typically administered once daily with food, preferably in the morning.
  • Regular monitoring via ACTH stimulation tests is necessary to fine-tune the dosage and ensure effectiveness.

What Ingredients Are in Vetoryl 10mg Capsules?

Each Vetoryl capsule contains:

Ingredient

Purpose

Trilostane

Cortisol synthesis inhibitor

Microcrystalline cellulose

Capsule filler

Gelatin capsule

Oral administration

Trilostane is a synthetic steroidogenesis inhibitor that blocks the enzyme 3β-hydroxysteroid dehydrogenase, leading to a reduction in adrenal cortisol production.

How Does Vetoryl Work in Dogs with Cushing’s Disease?

Vetoryl targets the overactive adrenal glands by inhibiting the enzyme responsible for cortisol production. In dogs with hyperadrenocorticism, this excess hormone leads to symptoms like excessive urination, hunger, and hair loss.

  • Trilostane blocks cortisol synthesis at the adrenal level.
  • Supports endocrine balance and reduces stress hormone buildup.
  • Offers a non-invasive alternative to surgery for adrenal tumors.

By restoring hormonal balance, Vetoryl helps your dog regain energy, appetite control, and overall vitality.

What Results Can I Expect with Vetoryl 10mg?

Dog parents usually start seeing improvements within 1–3 weeks, such as:

  • Reduced panting and water consumption
  • Less frequent urination
  • Brighter, more energetic mood
  • Noticeable weight stabilization and coat improvement

🐾 Veterinarians often consider a 25–30% reduction in cortisol levels a positive sign that Vetoryl is working.

Are There Any Side Effects of Vetoryl 10mg for Dogs?

While generally safe, Vetoryl may cause the following side effects:

  • Vomiting or diarrhea
  • Lethargy or loss of appetite
  • Weakness or collapse (in cases of overdose)
  • Electrolyte imbalances
  • Adrenal insufficiency (if improperly dosed)

If you notice signs like severe vomiting, low energy, or collapse, stop the medication and contact your vet immediately.

What Warnings Should I Know Before Using Vetoryl Trilostane for Dogs?

  • Not for use in pregnant dogs or those with kidney/liver dysfunction.
  • Dogs should undergo baseline blood work and ACTH stimulation testing before treatment.
  • Do not split or crush capsules.
  • Keep out of reach of children and other animals.
  • Monitor regularly for electrolyte levels and adrenal function.

Is Vetoryl Safe for Long-Term Use in Dogs?

Yes, Vetoryl is commonly prescribed for chronic, lifelong management of Cushing’s disease. However, it requires regular blood testing to ensure correct dosing and avoid complications like iatrogenic hypoadrenocorticism (Addison’s-like condition).

  • Most dogs tolerate it well with proper monitoring.
  • Your vet will schedule ACTH stimulation tests every few months.
  • Watch for subtle changes in behavior or appetite as early signs of overdose or underdose.

Is Vetoryl Suitable for All Dog Breeds and Sizes?

Vetoryl is safe for most adult dogs when used under veterinary supervision, but certain breeds with known adrenal sensitivity or underlying liver/kidney conditions may require extra caution. Ideal candidates:

  • Dogs over 3kg (smaller dogs may need adjusted dosages)
  • Not intended for puppies, pregnant females, or dogs with untreated kidney/liver issues
  • Breeds prone to endocrine issues (Poodles, Dachshunds, Boxers) may benefit the most

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Vetoryl 10mg Trilostane Capsules for Dogs FAQs 

What is Vetoryl 10mg used for in dogs?

Vetoryl 10mg is used to treat canine Cushing’s disease by reducing cortisol levels, managing symptoms like excessive thirst, bloating, and lethargy.

How long does it take for Vetoryl to work?

Visible improvements can occur within 1–2 weeks, but full therapeutic effect and stability may take several weeks of dosage adjustment and monitoring.

Can Vetoryl be used with other medications?

Yes, but always consult your vet. Some medications may interact with Trilostane, especially those affecting the liver or kidneys.

Is Vetoryl a lifelong treatment?

In most cases, yes. Dogs with Cushing’s often require continuous medication and regular monitoring to manage symptoms long-term.

What should I do if I miss a dose of Vetoryl?

Give the missed dose as soon as you remember, but skip it if it’s near the time of the next dose. Never double up.

Authoritative Resources for Further Reading:

  1. FDA - Vetoryl Drug Approval
  2. Merck Veterinary Manual – Cushing’s Syndrome in Dogs
  3. PetMD – Trilostane for Dogs

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