Simparica Trio for Dogs (Sarolaner, Moxidectin, and Pyrantel) 11.1-22.0 lbs

Simparica Trio Chewable Tablets for Dogs 11.1-22.0 lbs

All-in-One Flea, Tick & Heartworm Protection

Simparica Trio Chewable Tablets for Dogs 11.1-22.0 lbs are once-monthly, broad-spectrum parasite preventatives designed to protect small breed dogs from fleas, ticks, heartworm disease, roundworms, and hookworms.

Manufactured by Zoetis, this FDA-approved chewable tablet combines three potent active ingredients—Sarolaner, Moxidectin, and Pyrantel Pamoate—to deliver fast-acting, long-lasting parasite control in a single, palatable dose.

With its liver-flavored formulation, Simparica Trio simplifies parasite protection by eliminating the need for multiple medications or messy topical treatments. This convenient chew provides 30 days of continuous defense, ensuring your small dog remains safe from external and internal parasites year-round.

Also Available In:

Simparica Trio is available in different dosage strengths to ensure optimal protection for dogs of all sizes. Find the perfect dose for your furry friend:

✅ Simparica Trio Chewable Tablets for Puppies 2.8-5.5 lbs
✅ Simparica Trio Chewable Tablets for Small Dogs 5.6-11.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 22.1-44.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 44.1-88.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 88.1-132.0 lbs

Ensure your dog gets the right dosage for their size and weight to receive full-spectrum parasite protection. 🐶💙

Why Choose Simparica Trio Chewable Tablets for Dogs 11.1-22.0 lbs?

✔ Comprehensive Parasite Protection – Prevents heartworm disease, kills fleas & ticks, and treats intestinal parasites.
✔ Fast-Acting Formula – Starts working within 4 hours to kill fleas and within 8 hours to eliminate ticks.
✔ Extended Efficacy – Provides 30 days of uninterrupted protection per chew.
✔ Vet-Recommended & FDA-Approved – Trusted by veterinarians for safe and effective parasite prevention.
✔ Easy Administration – Palatable, liver-flavored chew ensures stress-free dosing without the hassle of spot-on applications.

Clinically Proven Effectiveness

How Do Simparica Trio Chewable Tablets for Dogs 11.1-22.0 lbs Work?

Simparica Trio uses a multi-action formula to target different parasites at various life stages. Each chewable tablet contains:

• Sarolaner (Isoxazoline-class) – Rapidly kills fleas before they lay eggs and eliminates 5 species of disease-carrying ticks to reduce the risk of Lyme disease, ehrlichiosis, and Rocky Mountain spotted fever.
• Moxidectin (Macrocyclic Lactone-class) – Disrupts the development of Dirofilaria immitis larvae, preventing heartworm disease transmitted by mosquitoes.
• Pyrantel Pamoate (Tetrahydropyrimidine-class) – Paralyzes and eliminates intestinal worms, including Toxocara canis (roundworms) and Ancylostoma caninum (hookworms), which can cause gastrointestinal and nutritional deficiencies in dogs.

By combining ectoparasiticide (flea and tick killer) and endoparasiticide (internal parasite control) properties, Simparica Trio offers complete protection with a single chewable tablet every month.

How to Use Simparica Trio Chewable Tablets for Dogs 11.1-22.0 lbs? 

Recommended Dosage

• Administer once a month as directed by your veterinarian.
• Can be given with or without food.
• If a dose is missed, administer it as soon as possible and continue the monthly schedule.

Why Should You Use Simparica Trio Year-Round?

Heartworm Prevention

• Prevents the development of Dirofilaria immitis larvae, transmitted through mosquito bites.
• Dogs should undergo heartworm testing before starting treatment to ensure they are not already infected.

Flea Control & Prevention

• Eliminates adult Ctenocephalides felis (cat fleas) before they lay eggs, stopping infestations at the source.
• Provides 30 days of flea protection with each dose.

Tick Treatment & Prevention

• Kills 5 tick species, including:
  • Deer ticks (Ixodes scapularis) – Primary carriers of Lyme disease.
  • Lone Star ticks (Amblyomma americanum) – Vectors of Ehrlichiosis.
  • American dog ticks (Dermacentor variabilis) – Associated with Rocky Mountain spotted fever.
  • Gulf Coast ticks (Amblyomma maculatum) – Transmitters of Hepatozoonosis.
  • Brown dog ticks (Rhipicephalus sanguineus) – Carriers of Babesiosis and Ehrlichiosis.

Roundworm & Hookworm Treatment

• Treats and controls Toxocara canis (roundworms), which can cause malnutrition and digestive issues.
• Eliminates Ancylostoma caninum (hookworms), a parasite that can lead to anemia and intestinal discomfort.

Simparica vs. Simparica Trio – What’s the Difference?

For broader parasite protection, some pet owners opt for Simparica Trio, which protects against:

If your dog also needs heartworm prevention, consider upgrading to Simparica Trio heartworm and flea prevention for complete parasite control.

Is Simparica Trio Safe? (Side Effects & Warnings)

Simparica Trio is safe for dogs 8 weeks and older weighing at least 2.8 lbs. However, some dogs may experience mild side effects.

Potential Side Effects:

• Vomiting
• Diarrhea
• Lethargy
• Loss of appetite
• Increased thirst or urination
• Muscle tremors (rare)

Warnings & Precautions:

⚠ Use with caution in dogs with a history of seizures or neurological disorders.
⚠ Not recommended for use in breeding, pregnant, or lactating dogs (safety not evaluated).
⚠ Store in a secure location away from children and pets to prevent accidental ingestion.

Shipping & Returns 

• Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.
• Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Simparica Trio Chewable Tablets for Dogs 11.1-22.0 - FAQs

1. What is Simparica Trio Chewable Tablets for Dogs 11.1-22.0 lbs used for?

Simparica Trio is a once-a-month chewable tablet that protects dogs 11.1-22.0 lbs from heartworms, fleas, ticks, roundworms, and hookworms.

2. How fast does Simparica Trio start working?

It begins killing fleas within 4 hours and ticks within 8 hours after administration.

3. Can Simparica Trio be given with food?

Yes, it can be given with or without food, and most dogs enjoy its liver-flavored taste.

4. Does Simparica Trio prevent Lyme disease?

Yes! By eliminating deer ticks, Simparica Trio helps reduce the risk of Lyme disease transmission.

5. What happens if I miss a dose?

Administer the missed dose immediately, then continue with the regular monthly schedule. If uncertain, consult your veterinarian.