Simparica Trio for Dogs (Sarolaner, Moxidectin, and Pyrantel) 22.1-44.0 lbs

Simparica Trio Chewable Tablets for Dogs 22.1-44.0 lbs

Complete Parasite Protection

Simparica Trio Chewable Tablets for Dogs 22.1-44.0 lbs offer comprehensive, all-in-one protection against fleas, ticks, heartworms, roundworms, and hookworms. Designed for medium-sized dogs, this once-monthly, liver-flavored chew makes parasite prevention easy and effective.

Manufactured by Zoetis, Simparica Trio is an FDA-approved, vet-recommended treatment that starts working within hours and provides 30 days of continuous protection. With just one chew, your dog gets fast-acting, broad-spectrum defense against harmful parasites—no need for multiple medications.

Also Available In:

Simparica Trio is available in different dosage strengths to ensure optimal protection for dogs of all sizes. Find the perfect dose for your furry friend:

✅ Simparica Trio Chewable Tablets for Puppies 2.8-5.5 lbs
✅ Simparica Trio Chewable Tablets for Dogs 5.6-11.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 11.1-22.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 44.1-88.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 88.1-132.0 lbs

Ensure your dog gets the right dosage for their size and weight to receive full-spectrum parasite protection. 🐶💙

Why Choose Simparica Trio Chewable Tablets for Dogs 22.1-44.0 lbs?

✔ 3-in-1 Parasite Defense – Prevents heartworm disease, eliminates fleas & ticks, and treats roundworms & hookworms.
✔ Fast & Effective – Kills fleas in 4 hours and ticks in 8 hours while ensuring month-long protection.
✔ Veterinarian-Recommended & FDA-Approved – Safe and trusted by vets for comprehensive parasite prevention.
✔ Tasty & Easy to Administer – Liver-flavored chewable eliminates the need for messy topical treatments.
✔ Proven Performance – Clinically tested for high efficacy against fleas, ticks, and intestinal parasites.

Clinically Tested Effectiveness

How Do Simparica Trio Chewable Tablets for Dogs 22.1-44.0 lbs Work?

Simparica Trio combines three active ingredients to deliver full-body parasite protection:

• Sarolaner – Quickly eliminates fleas before they lay eggs and kills 5 types of ticks, reducing disease risks.
• Moxidectin – Prevents heartworm disease by stopping the development of Dirofilaria immitis larvae.
• Pyrantel Pamoate – Treats and controls intestinal parasites like roundworms and hookworms, preventing digestive infections.

With one chew per month, Simparica Trio provides continuous, head-to-tail parasite defense for your dog.

How to Use Simparica Trio Chewable Tablets for Dogs 22.1-44.0 lbs?

(Dosage & Administration)

• Administer once a month as directed by your veterinarian.
• Can be given with or without food.
• If a dose is missed, give it immediately and resume the regular monthly schedule.

Why Is Year-Round Use Recommended?

Heartworm Prevention

• Protects against mosquito-transmitted heartworm disease.
• Dogs should be tested for heartworms before starting treatment.

Flea Control & Prevention

• Kills fleas before they reproduce, stopping infestations.
• Begins working within 4 hours and lasts 30 days.

Tick Treatment & Prevention

• Eliminates Lone Star ticks, Gulf Coast ticks, American dog ticks, Black-legged ticks (deer ticks), and Brown dog ticks.
• Kills ticks within 8 hours, reducing disease transmission risks.

Roundworm & Hookworm Treatment

• Treats Toxocara canis, Toxascaris leonina, Ancylostoma caninum, and Uncinaria stenocephala.
• Prevents digestive health issues and malnutrition caused by intestinal parasites.

Simparica vs. Simparica Trio – What’s the Difference?

For broader parasite protection, some pet owners opt for Simparica Trio 22.1-44 lbs 6 Month Supply, which protects against:

If your dog also needs heartworm prevention, consider upgrading to Simparica Trio heartworm and flea prevention 22.1-44 lbs for complete parasite control.

Is Simparica Trio Safe? (Side Effects & Warnings)

Simparica Trio is safe for dogs 8 weeks and older weighing at least 2.8 lbs. However, some dogs may experience mild side effects.

Potential Side Effects:

• Vomiting
• Diarrhea
• Lethargy
• Loss of appetite
• Increased thirst or urination
• Muscle tremors (rare)

Warnings & Precautions:

⚠ Use caution in dogs with a history of seizures or neurological disorders.
⚠ Not evaluated for use in breeding, pregnant, or lactating dogs.
⚠ Keep out of reach of children and pets to prevent accidental ingestion.

Shipping & Returns 

• Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

• Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Simparica Trio Chewable Tablets for Dogs FAQs

1. What are Simparica Trio Chewable Tablets for Dogs 22.1-44.0 lbs used for?

Simparica Trio is a once-monthly chewable tablet that prevents heartworms, kills fleas & ticks, and treats roundworms & hookworms in dogs weighing 22.1-44.0 lbs.

2. How fast does Simparica Trio start working?

It starts killing fleas within 4 hours and ticks within 8 hours after administration.

3. Can Simparica Trio be given with food?

Yes, it can be given with or without food, and most dogs enjoy its tasty liver flavor.

4. Does Simparica Trio help prevent Lyme disease?

Yes! By eliminating deer ticks (Ixodes scapularis), Simparica Trio reduces the risk of Lyme disease transmission.

5. What happens if I miss a dose?

If you miss a dose, administer it immediately, then continue with the regular monthly schedule. Consult your vet if unsure.