Simparica Trio for Small Dogs (Sarolaner, Moxidectin, and Pyrantel) 5.6-11.0 lbs

Simparica Trio Chews for Small Dogs 5.6-11.0 lbs

3-in-1 Flea, Tick & Heartworm Protection

Simparica Trio Chews for Dogs 5.6-11.0 lbs are once-monthly, broad-spectrum chewable tablets formulated to protect small breed dogs from fleas, ticks, heartworms, roundworms, and hookworms. Developed by Zoetis, this FDA-approved, veterinarian-recommended medication offers a fast-acting and long-lasting defense against both external and internal parasites.

This liver-flavored chew provides 30 days of continuous parasite prevention, eliminating the need for messy topical treatments or multiple medications. Designed specifically for toy and small dogs weighing between 5.6-11.0 lbs, Simparica Trio ensures year-round protection in a single, easy-to-administer chew.

Also Available In:

Simparica Trio is available in different dosage strengths to ensure optimal protection for dogs of all sizes. Find the perfect dose for your furry friend:

✅ Simparica Trio Chewable Tablets for Puppies 2.8-5.5 lbs
✅ Simparica Trio Chewable Tablets for Dogs 11.1-22.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 22.1-44.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 44.1-88.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 88.1-132.0 lbs

Ensure your dog gets the right dosage for their size and weight to receive full-spectrum parasite protection. 🐶💙

Why Choose Simparica Trio Chews for Small Dogs 5.6-11.0 lbs?

✔ Triple-Action Parasite Protection – Prevents heartworm disease, eliminates fleas and ticks, and treats intestinal worms.
✔ Fast-Acting & Long-Lasting – Starts killing fleas within 4 hours and ticks within 8 hours, offering month-long protection.
✔ Vet-Approved & FDA-Certified – Safe for small dogs as young as 8 weeks old, with a proven high safety margin.
✔ Highly Palatable Chew – No more struggling with tablets or messy spot-on treatments—delicious liver flavor makes dosing easy.
✔ Scientifically Proven Efficacy – Effectively eliminates 5 species of ticks, fleas, and gastrointestinal parasites.

Clinically Proven Effectiveness

How Do Simparica Trio Chews for Small Dogs 5.6-11.0 lbs Work?

Simparica Trio chews contain three active ingredients that work together to provide comprehensive parasite control:

• Sarolaner (Isoxazoline-class ectoparasiticide) – A fast-acting compound that kills fleas before they can lay eggs and eliminates ticks, reducing the risk of Lyme disease, Ehrlichiosis, and Anaplasmosis.
• Moxidectin (Macrocyclic lactone endoparasiticide) – Disrupts the development of Dirofilaria immitis (heartworm larvae), preventing heartworm disease caused by mosquito bites.
• Pyrantel Pamoate (Tetrahydropyrimidine-class anthelmintic) – Targets intestinal parasites, including roundworms and hookworms, preventing gastrointestinal complications.

By combining ectoparasiticidal (external parasite control) and endoparasiticidal (internal parasite control) properties, Simparica Trio offers full-body protection for small breed dogs.

How to Use Simparica Trio Chews for Small Dogs 5.6-11.0 lbs? 

Recommended Dosage

• Administer once per month as prescribed by your veterinarian.
• Can be given with or without food.
• If a dose is missed, administer as soon as possible and continue the monthly schedule.

Why Is Year-Round Protection Essential?

Heartworm Prevention

• Protects against Dirofilaria immitis, a mosquito-transmitted parasite that can cause fatal heartworm disease.
• Dogs should be tested for heartworm infection before starting Simparica Trio.

Flea Control & Prevention

• Kills adult Ctenocephalides felis (cat fleas) before they can reproduce, breaking the flea life cycle.
• Ensures 30 days of flea protection, reducing the risk of flea allergy dermatitis (FAD).

Tick Treatment & Prevention

Eliminates 5 common tick species, including:

• Deer ticks (Ixodes scapularis) – Vectors of Lyme disease.
• Lone Star ticks (Amblyomma americanum) – Carriers of Ehrlichiosis.
• American dog ticks (Dermacentor variabilis) – Associated with Rocky Mountain spotted fever.
• Gulf Coast ticks (Amblyomma maculatum) – Transmit Hepatozoonosis.
• Brown dog ticks (Rhipicephalus sanguineus) – Linked to Babesiosis and Ehrlichiosis.

Roundworm & Hookworm Treatment

• Treats Toxocara canis (roundworms), which can cause malnutrition and digestive issues.
• Eliminates Ancylostoma caninum (hookworms), a parasite that can lead to anemia and intestinal inflammation.

Simparica vs. Simparica Trio – What’s the Difference?

For broader parasite protection, some pet owners opt for Simparica Trio, which protects against:

If your dog also needs heartworm prevention, consider upgrading to Simparica Trio heartworm and flea prevention for complete parasite control.

Is Simparica Trio Chews Safe? (Side Effects & Warnings)

Simparica Trio is safe for dogs 8 weeks and older weighing at least 2.8 lbs. However, some dogs may experience mild side effects.

Possible Side Effects:

• Vomiting
• Diarrhea
• Lethargy
• Loss of appetite
• Increased thirst or urination
• Muscle tremors (rare)

Warnings & Precautions:

⚠ Use with caution in dogs with a history of seizures or neurological disorders.
⚠ Not recommended for breeding, pregnant, or lactating dogs (safety not evaluated).
⚠ Store safely away from children and pets to prevent accidental ingestion.

Shipping & Returns 

Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Simparica Trio Chews for Small Dogs 5.6-11.0 lbs - FAQs

1. What are Simparica Trio Chews for Dogs 5.6-11.0 lbs used for?

Simparica Trio is a once-a-month chewable tablet that protects dogs 5.6-11.0 lbs from fleas, ticks, heartworms, roundworms, and hookworms.

2. How quickly does Simparica Trio start working?

It starts killing fleas within 4 hours and ticks within 8 hours of administration.

3. Can Simparica Trio be given with food?

Yes, it can be given with or without food, and most dogs enjoy its liver-flavored taste.

4. Does Simparica Trio protect against Lyme disease?

Yes! By eliminating deer ticks, Simparica Trio helps reduce the risk of Lyme disease transmission.

5. What if I miss a dose?

Administer the missed dose immediately, then resume the regular monthly schedule. If unsure, consult your veterinarian.