Simparica Trio for Dogs (Sarolaner, Moxidectin, and Pyrantel) 88.1-132.0 lbs

Simparica Trio for Dogs 88.1-132.0 lbs

All-in-One Flea, Tick & Heartworm Protection

Simparica Trio for Dogs 88.1-132.0 lbs is a once-a-month chewable tablet that provides comprehensive parasite protection for large dogs. This vet-recommended, FDA-approved treatment defends against fleas, ticks, heartworms, roundworms, and hookworms in one easy-to-administer chew.

Manufactured by Zoetis, Simparica Trio combines three powerful ingredients—Sarolaner, Moxidectin, and Pyrantel—to deliver fast-acting, broad-spectrum defense against harmful parasites. Its delicious liver-flavored chew makes dosing stress-free, even for picky eaters.

Designed specifically for large breed dogs (88.1-132.0 lbs), Simparica Trio ensures year-round protection against dangerous parasites that can affect your dog's health and well-being.

Also Available In:

Simparica Trio is available in different dosage strengths to ensure optimal protection for dogs of all sizes. Find the perfect dose for your furry friend:

✅ Simparica Trio Chewable Tablets for Puppies 2.8-5.5 lbs
✅ Simparica Trio Chewable Tablets for Dogs 5.6-11.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 11.1-22.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 22.1-44.0 lbs
✅ Simparica Trio Chewable Tablets for Dogs 44.1-88.0 lbs

Ensure your dog gets the right dosage for their size and weight to receive full-spectrum parasite protection. 🐶💙

Why Choose Simparica Trio for Dogs 88.1-132.0 lbs?

✔ 3-in-1 Parasite Protection – Kills fleas and ticks, prevents heartworm disease, and treats roundworms and hookworms.
✔ Fast-Acting Formula – Begins killing fleas within 4 hours and ticks within 8 hours.
✔ Long-Lasting Defense – Provides 30 days of continuous protection per dose.
✔ Palatable, Easy-to-Give Chew – No messy topicals or difficult pills—just a tasty liver-flavored chew.
✔ Veterinarian-Recommended & FDA-Approved – Trusted by vets for safe, effective parasite control.

Proven Effectiveness

How Does Simparica Trio for Dogs 88.1-132.0 lbs Work?

Simparica Trio delivers complete parasite protection using three active ingredients:

• Sarolaner – A fast-acting isoxazoline-class compound that kills fleas before they lay eggs and eliminates 5 species of disease-carrying ticks.
• Moxidectin – Prevents heartworm disease by targeting immature Dirofilaria immitis larvae before they develop into adult heartworms.
• Pyrantel Pamoate – Treats and controls intestinal parasites like roundworms and hookworms, reducing the risk of infections.

Unlike topical treatments, Simparica Trio offers full-body protection in a single chewable tablet every month.

How to Use Simparica Trio for Dogs 88.1-132.0 lbs? (Dosage & Administration)

Dosage Chart

• Give once a month as prescribed by your veterinarian.
• Can be administered with or without food.
• If a dose is missed, administer it immediately and resume the monthly schedule.

Why Use Simparica Trio Year-Round?

Heartworm Prevention

• Protects against Dirofilaria immitis, a potentially fatal parasite transmitted by mosquitoes.
• Dogs should be tested for heartworm before starting treatment.

Flea Control & Prevention

• Kills adult fleas before they can lay eggs, breaking the infestation cycle.
• Starts working within 4 hours and provides continuous flea protection for 30 days.

Tick Treatment & Prevention

• Eliminates Lone Star ticks, Gulf Coast ticks, American dog ticks, Black-legged ticks (deer ticks), and Brown dog ticks.
• Starts killing ticks within 8 hours, reducing the risk of tick-borne diseases.

Roundworm & Hookworm Treatment

• Treats and controls Toxocara canis, Toxascaris leonina, Ancylostoma caninum, and Uncinaria stenocephala.
• Helps prevent gastrointestinal issues and nutritional deficiencies caused by intestinal worms.

Simparica vs. Simparica Trio – What’s the Difference?

For broader parasite protection, some pet owners opt for Simparica Trio 22.1-44 lbs 6 Month Supply, which protects against:

If your dog also needs heartworm prevention, consider upgrading to Simparica Trio heartworm and flea prevention 22.1-44 lbs for complete parasite control.

Is Simparica Trio Safe? (Side Effects & Warnings)

Simparica Trio is safe for dogs 8 weeks and older weighing at least 2.8 lbs. However, as with any medication, some dogs may experience mild side effects.

Possible Side Effects:

• Vomiting
• Diarrhea
• Lethargy
• Decreased appetite
• Increased thirst or urination
• Muscle tremors (rare)

Warnings & Precautions:

⚠ Use with caution in dogs with a history of seizures or neurological disorders.
⚠ Not evaluated for use in breeding, pregnant, or lactating dogs.
⚠ Keep out of reach of children and pets to prevent accidental overdose.

 Shipping & Returns 

• Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

• Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Frequently Asked Questions (FAQs)

1. What is Simparica Trio for Dogs 88.1-132.0 lbs used for?

Simparica Trio is a monthly chewable that protects against fleas, ticks, heartworm disease, roundworms, and hookworms in dogs weighing 88.1-132.0 lbs.

2. How fast does Simparica Trio start working?

Simparica Trio starts killing fleas within 4 hours and ticks within 8 hours after administration.

3. Can I give Simparica Trio with food?

Yes! Simparica Trio can be given with or without food, and most dogs enjoy its liver-flavored taste.

4. Does Simparica Trio help prevent Lyme disease?

Yes! By killing deer ticks (Ixodes scapularis), Simparica Trio helps reduce the risk of Lyme disease transmission.

5. What if I miss a dose of Simparica Trio?

If you miss a dose, administer it immediately, then continue with the regular monthly schedule. If unsure, consult your veterinarian.