Vetoryl Capsules (Trilostane) for Dogs, 5mg

Vetoryl 5 mg for Dogs

Effective Treatment for Canine Cushing's Disease

Vetoryl 5 mg Capsules is a veterinary prescription medication used in the management of canine Cushing’s disease (also known as hyperadrenocorticism). It contains the active ingredient trilostane, a potent adrenal suppressant that helps regulate the overproduction of cortisol – the root cause of Cushing’s syndrome in dogs.

This medication is primarily prescribed for:

• Pituitary-dependent hyperadrenocorticism (PDH) – the most common type of Cushing's in dogs
  
• Adrenal-dependent hyperadrenocorticism (ADH) – less common but equally serious
  
• Helping manage symptoms like excessive thirst, panting, hair loss, and pot-bellied appearance
  

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Save time and money with our AutoShip option—get Vetoryl 5mg capsules for dogs delivered on schedule with extra discounts on every order!

Also Available in Other Vetoryl Strengths for Dogs

To ensure accurate and safe dosing based on your dog’s weight and condition, HardyPaw offers Vetoryl in multiple strengths. Choose the right option as prescribed by your veterinarian:

• Vetoryl 5mg for Dogs – Ideal for toy breeds or very small dogs under 5 lbs (you are viewing this product)
• Vetoryl 10mg for Dogs – Suitable for small dogs weighing up to 10 lbs
• Vetoryl 20mg for Dogs – A mid-range option for light to medium-sized dogs
• Vetoryl 30mg for Dogs – Commonly prescribed for moderate weight dogs
• Vetoryl 60mg for Dogs – Best for medium to large breeds needing stronger control
• Vetoryl 120mg for Dogs – Designed for large and giant breeds or dogs with severe symptoms

📌 Always follow your vet’s dosing recommendation and adjust strength as needed based on follow-up testing and response.

What Are the Benefits of Vetoryl 5 mg for Dogs?

Vetoryl 5 mg stands out as the go-to treatment for early-stage or small-breed dogs needing precise dosing for adrenal regulation. Here's why pet parents and vets trust it:

• Targeted cortisol control with trilostane to restore hormonal balance
  
• Improves quality of life by relieving clinical signs like lethargy and skin issues
  
• Supports adrenal health in both pituitary and adrenal-dependent forms
  
• 5 mg strength is ideal for small dogs or dogs just beginning therapy
  
• Once-daily oral dosing makes it easy to incorporate into routines
  

Unlike some alternatives, Vetoryl does not simply mask symptoms—it addresses the source of the disease.

How Do I Know If My Dog Needs Vetoryl 5 mg?

Many pet parents don’t recognize early signs of Cushing's disease. Common symptoms that may indicate your dog needs Vetoryl include:

• Increased thirst and urination
  
• Pot-bellied appearance
  
• Thinning hair or hair loss
  
• Excessive panting
  
• Lethargy and muscle weakness
  
• Skin infections or slow wound healing
  

If your dog shows multiple symptoms, consult a veterinarian for diagnostic testing like ACTH stimulation test or low-dose dexamethasone suppression test (LDDST).

How to Use Vetoryl 5 mg Capsules for Dogs? (Dosage and Administration)

Always administer Vetoryl exactly as prescribed by your veterinarian. These instructions are general guidelines:

• Administer once daily with food, ideally in the morning.
• Do not open or crush the capsules.
  
• Capsules are available in multiple strengths—5 mg is typically used for small dogs or dose titration.
  
• Regular ACTH stimulation tests and bloodwork are essential for monitoring and dose adjustment.
  

Always consult your veterinarian for exact dosage instructions depending on your pet's condition.

Can Vetoryl Be Combined With Other Medications?

Always check with your veterinarian, but generally:

Safe combinations (under vet supervision):

• Heart medications (e.g., Pimobendan)
  
• Thyroid supplements
  
• Antibiotics
  

Use caution with:

• NSAIDs (non-steroidal anti-inflammatory drugs)
  
• ACE inhibitors
  
• Diuretics
  

Combining drugs that affect potassium or blood pressure may require dose adjustments or close monitoring.

What Are the Ingredients in Vetoryl 5 mg?

Trilostane works by inhibiting the enzyme 3β-hydroxysteroid dehydrogenase, thereby limiting cortisol production in the adrenal glands.

What Are the Side Effects of Vetoryl in Dogs?

While Vetoryl 5 mg is generally well-tolerated, side effects may occur:

• Vomiting or diarrhea
  
• Lethargy or depression
  
• Loss of appetite
  
• Electrolyte imbalances (low sodium/high potassium)
  
• Adrenal necrosis (rare but serious)
  

Contact your vet immediately if your dog shows signs of:

• Collapse
  
• Severe weakness
  
• Persistent vomiting
  

What Warnings and Precautions Should I Know?

• Not for use in dogs under 3 kg (6.6 lbs) or dogs that are pregnant or lactating
  
• Caution in dogs with liver, kidney, or heart disease
  
• Regular blood monitoring is critical to avoid hypoadrenocorticism (Addison’s disease)
  

Store Vetoryl at room temperature, away from moisture and light. Keep out of reach of children and other animals.

How Long Will My Dog Need to Take Vetoryl?

Vetoryl is generally a lifelong treatment for managing Cushing’s disease. With consistent use:

• Symptoms may significantly improve in 2–4 weeks
  
• Dogs can live comfortably with proper monitoring
  
• Periodic ACTH tests are necessary to ensure the dose remains effective and safe
  

Stopping the medication or skipping doses can cause a relapse of symptoms.

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Vetoryl 5 mg for Dogs FAQs

What is Vetoryl 5 mg used for?

Vetoryl 5 mg is used to treat Cushing’s disease in dogs, regulating excess cortisol levels and improving symptoms like panting, hair loss, and lethargy.

How long does Vetoryl take to work in dogs?

Most dogs show improvement within 7 to 14 days, but full hormone stabilization may take a few weeks. Regular blood tests help fine-tune the dosage.

Can Vetoryl cure Cushing’s disease?

Vetoryl does not cure Cushing’s but manages symptoms long-term. It must be given consistently to maintain hormonal balance.

Is it safe to stop Vetoryl suddenly?

No, stopping suddenly can cause hormonal rebound and worsen symptoms. Always consult your vet before changing any dosage or discontinuing use.

What happens if I miss a dose of Vetoryl?

Give the missed dose as soon as you remember, but if it’s close to the next dose, skip it. Do not double up to compensate for the missed one.

Clinical Research: 

• https://www.aaha.org/newstat/publications/monitoring-strategies-for-trilostane-therapy-in-dogs-with-cushings-syndrome/
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855282/