Sileo (dexmedetomidine oromucosal) Oromucosal Gel for Dogs

Sileo (dexmedetomidine oromucosal) Oromucosal Gel for Dogs

Sileo (dexmedetomidine oromucosal gel) is the first FDA-approved treatment specifically designed to address noise aversion in dogs, a common condition where loud or sudden sounds like fireworks, thunderstorms, or construction noise trigger anxiety in pets. This innovative gel offers a calming effect by targeting norepinephrine, a brain neurotransmitter associated with stress and anxiety, helping your dog remain relaxed yet alert.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

What Are the Benefits of Sileo for Dogs?

Sileo is a trusted solution for noise aversion, offering several key benefits:

• Fast-Acting Relief: Takes effect in just 20–30 minutes to alleviate anxiety during stressful events.
• Non-Sedative Action: Calms your dog without causing drowsiness, allowing them to interact normally with you.
• Easy-to-Use Gel: Administered between the dog’s cheek and gums for quick absorption via the mucous membranes.
• Long-Lasting Effect: Provides up to 3 hours of relief, covering most noisy scenarios.
• Safe and Well-Tolerated: Minimal side effects when used as directed.

How Do You Use Sileo Gel for Dogs?

Administering Sileo is straightforward but requires careful attention to detail:

1. Prepare: Wear gloves to avoid contact with the gel.
2. Measure the Dose: Follow your vet's dosage chart, calibrated based on your dog’s weight (1 dot = 0.25 mL).
3. Apply the Gel: Place the prescribed amount between the dog’s cheek and gums. Avoid letting your pet swallow it.
4. Avoid Food or Treats: Do not feed your dog for 15 minutes after application to ensure effective absorption.

Important Note: If more than 6 dots are required, divide the dose evenly between both sides of the mouth. Always consult your vet for precise dosing instructions.

What Are the Ingredients in Sileo?

The active ingredient in Sileo is dexmedetomidine hydrochloride, a selective alpha-2 adrenergic receptor agonist. This compound helps reduce anxiety by inhibiting norepinephrine activity.

Are There Any Side Effects of Sileo Oromucosal Gel for Dogs?

While generally well-tolerated, some dogs may experience:

• Mild Sedation: Slight drowsiness or lethargy.
• Gastrointestinal Upset: Vomiting or diarrhea.
• Pale Gums: Indicating reduced blood flow.
• Hypersalivation: Increased drooling.
• Decreased Heart Rate: Slower-than-normal heart rate (bradycardia).

If any severe side effects or signs of an allergic reaction (such as swelling, difficulty breathing, or extreme lethargy) occur, contact your veterinarian immediately.

What Precautions Should Be Taken When Using Sileo Oromucosal Gel for Dogs?

• Medical History: Inform your veterinarian of any existing health conditions, especially cardiovascular diseases.
• Drug Interactions: Discuss any other medications or supplements your dog is taking to avoid potential interactions.
• Allergies: Do not administer to dogs with known hypersensitivity to dexmedetomidine or similar drugs.
• Pregnancy and Lactation: Use with caution in pregnant or lactating animals; consult your veterinarian for guidance.

How Should Sileo Be Stored?

To maintain effectiveness:

• Store syringes in their original packaging, away from light.
• Keep at a controlled room temperature of 68°–77°F.
• Use the contents within 4 weeks after opening.

Shipping & Returns 

Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

FAQs - Sileo Oromucosal Gel for Dogs

What is Sileo Oromucosal Gel used for?

Sileo Oromucosal Gel is used to treat noise aversion in dogs, a condition characterized by fear or anxiety triggered by loud or sudden sounds like fireworks, thunderstorms, or construction noise. The gel helps calm your dog without causing sedation, enabling them to remain alert and comfortable during stressful events.

Can Sileo Oromucosal Gel help with other anxiety types in dogs?

Sileo Oromucosal Gel is specifically approved for noise aversion. While it targets anxiety linked to loud noises, it is not intended for other types of anxiety, such as separation anxiety or travel-related stress. Consult your veterinarian for alternative treatments.

How can I tell if my dog needs Sileo Oromucosal Gel?

Dogs showing signs like trembling, hiding, panting, pacing, barking, or destructive behavior during loud noises may benefit from Sileo Oromucosal Gel. A veterinarian can diagnose noise aversion based on these symptoms and recommend the appropriate treatment.

Is Sileo Oromucosal Gel safe for all dog breeds and sizes?

Sileo Oromucosal Gel is generally safe for all dog breeds and sizes when used according to your veterinarian’s dosage recommendations. However, it should not be used in dogs with severe heart or liver conditions without prior veterinary advice.

How should I prepare my dog before administering Sileo Oromucosal Gel?

Ensure your dog is calm and avoid feeding them for at least 15 minutes before application. Wear gloves when handling the gel and follow the vet’s prescribed dose based on your dog’s weight to ensure safe and effective administration.

Can I use Sileo Oromucosal Gel for recurring noise events?

Yes, Sileo Oromucosal Gel can be used for recurring noise events, but doses must be spaced at least 2 hours apart. Always consult your veterinarian if multiple applications are needed over a short period.

What happens if my dog swallows Sileo Oromucosal Gel?

If your dog swallows Sileo Oromucosal Gel, its effectiveness may decrease since it is designed for absorption through the cheek and gums. Avoid re-dosing for at least 2 hours and consult your vet if you have concerns.

Are there any restrictions on activities after using Sileo Oromucosal Gel?

Your dog should remain indoors or in a safe environment after administration, as they may experience mild sedation or reduced activity. Monitor them for any signs of side effects and avoid vigorous physical activities immediately following the dose.

Can I give Sileo Oromucosal Gel to my puppy?

Sileo Oromucosal Gel can be used in puppies if prescribed by a veterinarian. However, the dosage must be carefully adjusted based on their weight and age. Always consult your vet before administering to young dogs.

Is there a risk of dependency or long-term side effects with Sileo Oromucosal Gel?

Sileo Oromucosal Gel is not habit-forming and is intended for short-term use during specific noise events. When used as directed, the risk of long-term side effects is minimal. Always follow your vet’s instructions for safe usage.

Additional Resources

For more information on Sileo Oromucosal Gel and its use in veterinary medicine, consider the following reputable sources:

• https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8113cc85-cd1e-4edc-b933-51bdbd1d8b64
• https://ec.europa.eu/health/documents/community-register/2015/20150610131892/anx_131892_en.pdf

These resources offer valuable insights into the proper use and considerations when administering Sileo Oromucosal Gel to your dog.