Advantage II Flea Control for Large Dogs (21-55 lbs) Red Box

Comprehensive Flea Prevention and Treatment for Dogs

Product Description

Advantage II for large dogs provides fast, effective protection against fleas, flea larvae, flea eggs, and lice, and prevents re-infestation. It is waterproof and easy to apply, supporting healthy skin and coat while keeping your dog comfortable and flea-free for up to 30 days. It begins killing adult fleas within 12 hours and also helps treat and control chewing lice infestations effectively. 

Benefits

• Flea Protection: Provides effective flea control for dogs 21–55 pounds.
• Easy Application: Monthly topical treatment is simple to apply, making flea prevention stress-free for pet owners.
• Total Flea Control: Kills adult fleas, flea larvae, and flea eggs through direct contact quickly and effectively.
• Fast-Acting Formula: Begins killing fleas the same day and continues protecting your dog for 30 days.
• Waterproof & Fragrance-Free: Topical formula is waterproof after 24 hours and free from fragrances for added convenience.
• Vet-Recommended Solution: Trusted by veterinarians, it ensures simple, monthly protection against fleas without prescriptions or oral medications.

Variants

• Small Dogs: 3–10 lbs
• Medium Dogs: 11–20 lbs
• Large Dogs: 21–55 lbs
• Extra Large Dogs: Over 55 lbs

Ingredients

Active Ingredients

Imidacloprid and Pyriproxyfen. 

Composition Table 

How to Use

Directions for Use

• Opening the Tube: Ensure the tube is at the pouch’s bottom. Use scissors to cut across the pouch top carefully.
• Selecting the Correct Product: Choose the appropriate Advantage II formula based on your dog’s weight category before applying the treatment.
• Preparing for Application: Bathe your dog prior to application and ensure they remain dry for 24 hours afterward.
• Applying the Treatment for Small Dogs (3–10 lbs): Hold the tube upright, remove the cap, and apply the contents directly to the skin between the shoulder blades.
• Applying for Medium to Extra-Large Dogs (11–20, 21–55 lbs, and over 55): Part the fur in several spots along the back, applying evenly from the shoulder blades to the tail.
• After Application and Disposal: Discard the empty tube safely, and do not reuse it. Repeat treatment monthly or as the veterinarian recommends.

Additional Information

Precautions

• General Safety Warning: Keep product out of children’s reach. Use cautiously to prevent accidental swallowing or contact incidents.
• Avoid Human Exposure: Avoid contact with eyes, skin, or clothing. Wash thoroughly after handling and before eating food.
• Application on Puppies: Do not use on puppies younger than 7 weeks old or weighing less than recommended.
• Species Restriction: Use only on dogs. Never apply this product to cats or other household animals.
• Sensitive or Sick Dogs: Avoid use on debilitated, aged, pregnant, or nursing dogs unless directed by a veterinarian.
• Veterinary Consultation: If irritation, discomfort, or allergic reactions occur, consult a veterinarian immediately before further applications. 

Possible Side Effects

• Post-Application Monitoring: Monitor your dog closely after each application to identify any unusual reactions or signs of discomfort.
• Skin Irritation Signs: Side effects may include redness, scratching, or visible skin irritation following product application.
• Discomfort Symptoms: Watch for signs of general discomfort such as itching, restlessness, or mild skin sensitivity.
• Gastrointestinal Reactions: Some dogs may experience vomiting, diarrhea, or mild stomach upset after receiving the treatment.
• Severe Side Effects: If lethargy or other concerning reactions appear, discontinue use immediately and consult your veterinarian.
• Veterinary Contact Information: For professional guidance regarding adverse effects, contact your veterinarian or call 1-800-422-9874 immediately. 

Storage and Disposal Instructions

• Prevent Contamination: Do not contaminate water, food, or feed by improper product storage, disposal, or handling procedures.
• Pesticide Storage: Keep in a cool, dry area that is inaccessible to both children and household pets.
• Container Handling: Use only nonrefillable containers; do not attempt to reuse or refill after initial product use.
• Empty Container Disposal: Place empty containers in household trash or offer them for recycling when local facilities permit.
• Partly Filled Container Disposal: Call your local waste agency or 1-800-422-9874 for detailed disposal instructions and guidance.
• Product Disposal Warning: Never pour unused pesticide product into indoor or outdoor drains to prevent environmental contamination.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Frequently Asked Questions

Q1: How quickly does Advantage II start working on my dog?

Ans: Advantage II begins killing adult fleas within 12 hours of application. It also targets flea larvae, flea eggs, and chewing lice, preventing re-infestation while keeping your dog comfortable and protected for a full 30 days.

Q2: How often should I apply Advantage II for effective flea control?

Ans: For optimal flea prevention, Advantage II should be applied once every 30 days. This monthly topical treatment provides ongoing protection against adult fleas, larvae, eggs, and chewing lice, eliminating the need for oral medications or prescription interventions.

Q3: Can I bathe my dog after applying Advantage II?

Ans: Yes, but you should wait 24 hours after the application. The formula is waterproof, so normal bathing or light rain won’t reduce its effectiveness once fully absorbed by the skin.

Q4: Is Advantage II safe for puppies and small dogs?

Ans: Advantage II is safe for puppies at least seven weeks old and weighing 3–10 pounds. It should not be used on younger or underweight puppies, and application instructions must be followed carefully for safety.

Q5: Are there any side effects I should watch for after treatment?

Ans: Some dogs may experience mild skin irritation, redness, scratching, or digestive upset, such as vomiting or diarrhea. If severe reactions or lethargy occur, discontinue use and contact a veterinarian immediately.

Q6: Can Advantage II be used on other pets besides dogs?

Ans: No, this product is specifically formulated for dogs. Applying it to cats or other household pets can be risky and may cause serious health issues. Always follow species-specific guidelines carefully.