Azathioprine Tablets for Dogs & Cats, 50mg

Azathioprine tablet is a powerful immunosuppressive medication used to manage autoimmune diseases and chronic inflammatory conditions in dogs and cats. These conditions, which cause the immune system to attack the body’s tissues, can result in severe discomfort, organ damage, and even life-threatening complications. 

In dogs, Azathioprine is commonly prescribed for conditions such as immune-mediated hemolytic anemia (IMHA), inflammatory bowel disease (IBD), and various autoimmune skin disorders. 

In cats, while its use is more cautious due to their sensitivity, it can be critical in treating similar severe autoimmune conditions. Regular monitoring and veterinary supervision are essential to ensure safe and effective treatment for both species.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Please note that the product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference.

NOTE: For generic medications, the picture displayed may not depict the actual product. Generic medication may vary from one order to the next by size, color, and shape depending on the manufacturer. 

Benefits of Azathioprine Tablets

• Immune Modulation: Suppresses excessive immune responses that cause autoimmune diseases, reducing inflammation and damage to healthy tissues.
• Symptom Relief: Alleviates symptoms like pain, swelling, and discomfort associated with chronic autoimmune conditions.
• Versatile Treatment: Effective for a wide range of conditions, including IMHA, IBD, and autoimmune skin disorders in dogs, and severe autoimmune diseases in cats.
• Long-Term Management: Suitable for chronic conditions requiring extended treatment, with dosing adjustments to minimize side effects.
• Reduced Side Effects: With proper monitoring, Azathioprine has a relatively low risk of severe side effects, making it a safer option for long-term use.
• Cost-Effective: Offers a cost-effective solution for managing complex autoimmune diseases over time.
• Combination Therapy: Can be used alongside other medications, like corticosteroids, to enhance overall treatment efficacy.

Subscription and Purchase Information

Buying Options and Discounts: Purchase Azathioprine Tablets, in a convenient 3-week, 1, 2, 3, and 6-month supply pack. Subscribe for regular shipments to ensure you never miss a dose and enjoy discounts on your purchases.

Order online for hassle-free delivery to your doorstep.

Ingredients

• Primary Ingredient: Azathioprine, which suppresses the immune system to reduce the effects of autoimmune diseases.
• Secondary Ingredients: Include fillers, stabilizers, and other compounds that ensure the medication is delivered effectively and consistently.

How Does It Work?

• Azathioprine works by inhibiting the synthesis of DNA in rapidly dividing immune cells, particularly T-lymphocytes. 
• By suppressing these cells, the medication reduces the immune system’s ability to attack the body’s tissues, thus controlling inflammation and other symptoms of autoimmune diseases. 
• The drug’s effects are gradual, with improvements typically seen over several weeks as it accumulates in the bloodstream.

Dosage and Administration

Give by mouth according to your vet's instructions. 

Frequency

• For dogs, Azathioprine is generally administered once daily or every other day, depending on the severity of the condition and the animal's response to treatment. 
• In cats, the dosage is much lower, and the frequency is carefully adjusted due to their sensitivity to the drug. 
• The exact dosage and frequency should always be determined by a veterinarian based on the pet's specific needs.

Consistency

• Consistency in administration is crucial for maintaining stable blood levels of the medication, which ensures effective suppression of the immune response.
• It’s recommended to give Azathioprine at the same time each day, with food, to reduce the risk of gastrointestinal upset.

Side Effects of Azathioprine Tablets

Azathioprine, while effective in managing autoimmune conditions in dogs, can cause several side effects, particularly if not closely monitored. Below is a comprehensive list of potential side effects:

• Bone Marrow Suppression: This can lead to anemia, low white blood cell counts, and thrombocytopenia (low platelet count), increasing the risk of infections and bleeding.
• Gastrointestinal Issues: Common symptoms include vomiting, diarrhea, and loss of appetite.
• Liver Toxicity: Elevated liver enzymes may occur, potentially leading to liver dysfunction or damage over time.
• Pancreatitis: Inflammation of the pancreas, which can cause severe abdominal pain, vomiting, and diarrhea.
• Increased Risk of Infections: Due to the suppression of the immune system, dogs may become more susceptible to infections.
• Fatigue and Lethargy: Dogs may appear unusually tired or weak as their body adjusts to the medication.
• Bruising or Bleeding: Easy bruising or prolonged bleeding from minor cuts may occur due to the effects on blood cells.
• Fever: An elevated temperature may indicate an infection or an adverse reaction to the medication.
• Hair Loss or Skin Changes: Some dogs may experience thinning of the coat or changes in skin texture.

Specific to Cats

Higher Sensitivity: Cats are more sensitive to Azathioprine, with an increased risk of severe bone marrow suppression and liver toxicity, making close monitoring essential.

Monitor your pet closely while on Azathioprine and report any unusual symptoms to your veterinarian for appropriate management. Regular blood tests are critical to detect early signs of serious side effects.

Precautions

• Both dogs and cats should undergo thorough veterinary assessments, including blood tests, before starting Azathioprine. 
• Regular monitoring is essential throughout the treatment to detect potential side effects early, especially bone marrow suppression and liver toxicity. 
• Due to the drug’s immunosuppressive effects, pets should be protected from exposure to infections.

Storage

• Store Azathioprine at room temperature, away from moisture and direct sunlight.
• Keep the medication in a secure location, out of reach of children and pets. 
• Ensure the container is tightly closed when not in use to maintain the medication’s potency.

Shipping & Returns 

Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

FAQs - Azathioprine Tablets for Dogs & Cats

Q: How long does it take for Azathioprine to work in dogs and cats?

A: Azathioprine usually takes 2-4 weeks to start showing effects. Regular monitoring by your vet is crucial during this period to assess the pet’s response to the medication.

Q: Can Azathioprine be used alongside other treatments?

A: Yes, it can be combined with other medications like corticosteroids for enhanced effectiveness, but always consult your vet to avoid interactions.

Q: What are the signs of an overdose in dogs and cats?

A: Signs of overdose include severe vomiting, diarrhea, lethargy, and abnormal bruising or bleeding. If an overdose is suspected, seek veterinary care immediately.

Q: How is Azathioprine dosed differently for dogs and cats?

A: Dogs generally receive higher doses than cats, who require much lower doses due to their increased sensitivity. Always follow your vet's specific dosage instructions.

Q: Is Azathioprine safe for long-term use in both species?

A: With proper monitoring, Azathioprine can be safely used long-term in both dogs and cats. Regular blood tests are essential to detect potential side effects early.

Q: What precautions should I take when handling Azathioprine?

A: Wear gloves when handling Azathioprine tablets, especially if you are pregnant or have compromised immunity, as the medication can be harmful if ingested or absorbed through the skin.

Q: Can Azathioprine cause hair loss in dogs or cats?

A: While rare, some pets may experience hair thinning or loss as a side effect. Consult your vet if you notice any changes in your pet’s coat or skin.

Q: How often should my pet have blood tests while on Azathioprine?

A: Initially, blood tests are recommended every 2-4 weeks, then every 1-3 months once the dosage is stabilized, to monitor for bone marrow suppression or liver toxicity.

Q: What should I do if I miss a dose?

A: If you miss a dose, give it as soon as you remember unless it’s close to the next scheduled dose. Do not double up doses. Resume the regular dosing schedule as instructed by your vet.

Q: Is there a risk of drug interactions with Azathioprine?

A: Yes, Azathioprine can interact with other medications. Always inform your vet of all medications and supplements your pet is taking to avoid harmful interactions.

Clinical Research

https://meridian.allenpress.com/jaaha/article-abstract/60/3/105/500367/Filgrastim-Use-in-the-Treatment-of-Azathioprine