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Barrier Topical Solution for Dogs, 20.1-55 lbs (Pink)

$10.99

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Prescription Required

Aurora Pharmaceutical SKU: 5107210003-1

Size (Dose): 1 Dose (1-mos. supply)
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Barrier Topical Solution for Dogs 20.1-55 lbs

Barrier Topical Solution for Dogs (20.1–55 lbs) is a veterinary-prescribed once-a-month topical treatment designed to protect medium to large-sized dogs from heartworms, fleas, ear mites, mange, and intestinal parasites. Formulated with imidacloprid and moxidectin, two trusted parasiticides, this broad-spectrum solution not only treats but also prevents recurring infestations, providing reliable 6-month protection per box.

Ideal for dogs weighing between 20.1 to 55 lbs, Barrier is a systemic antiparasitic that delivers both preventive and therapeutic efficacy with just one easy-to-apply monthly dose. It is especially effective against Dirofilaria immitis (canine heartworm), which can cause severe pulmonary damage if untreated.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Also Available in Other Dog Weight Ranges

Barrier for Dogs is formulated in multiple strengths to ensure precise and safe dosing for dogs of all sizes. Always choose the variant that matches your dog’s current weight for maximum efficacy and safety.

What Are the Benefits of Barrier for Dogs 20.1–55 lbs?

Barrier Topical Solution provides multi-target protection that outperforms many single-parasite treatments. It is a cost-effective and convenient solution for busy pet parents.

  • Heartworm prevention – Protects against deadly heartworm disease.
  • Kills adult fleas and prevents flea infestations.
  • Eliminates mites causing sarcoptic mange.
  • Treats and controls roundworms & hookworms.
  • Monthly dosing ensures ongoing protection without daily pills.
  • Waterproof formula—retains efficacy after bathing or swimming.
  • Easy spot-on application – no need for oral medication.
  • FDA-approved and veterinarian-recommended solution.

How to Use Barrier Topical Solution for Dogs 20.1–55 lbs? (Directions for Use)

  • Apply one tube (2.5 mL) topically once every 30 days.
  • Part the dog's hair at the base of the neck and apply the solution directly on the skin.
  • Ensure application site is dry and that your dog cannot lick the area.
  • Do not bathe or let your dog swim for at least 4 days post-application.

🐾 Tip: Consistency is key. Apply on the same date each month to ensure uninterrupted protection.

What Are the Active Ingredients in Barrier for Dogs 20.1–55 lbs?

Ingredient

Purpose

Imidacloprid (10%)

Insecticide that kills adult fleas by disrupting their central nervous system.

Moxidectin (2.5%)

Antiparasitic macrocyclic lactone effective against heartworms and intestinal worms.

Inert ingredients make up the rest of the formulation.

Are There Any Side Effects of Barrier 20.1–55 lbs for Dogs?

Most dogs tolerate Barrier well, but mild reactions can occur in some cases:

  • Temporary skin irritation or hair loss at the application site
  • Lethargy, vomiting, or incoordination (rare)
  • Hypersalivation if ingested

⚠️ If side effects persist or worsen, consult your veterinarian immediately.

What Warnings and Precautions Should I Know?

  • Do NOT administer orally. This product is for topical use only.
  • Keep away from eyes, mouth, and mucous membranes.
  • Avoid contact with other pets until the solution dries.
  • Wash hands thoroughly after use.
  • Store in a cool, dry place out of reach of children and animals.

Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Barrier for Dogs 20.1–55 lbs FAQs 

What is Barrier for Dogs 20.1–55 lbs used for?

Barrier is used to prevent heartworm disease and treat/control fleas, sarcoptic mange, hookworms, and roundworms in dogs between 20.1–55 lbs.

How long does Barrier last after application?

Each dose offers 30 days of protection. One 6-pack provides a 6-month supply for consistent, year-round defense.

Is Barrier safe for pregnant or nursing dogs?

Consult your veterinarian before using this product on breeding, pregnant, or lactating dogs.

Can I bathe my dog after applying Barrier?

Wait at least 4 days after application before bathing or letting your dog swim to ensure full efficacy.

How is Barrier different from other flea and heartworm treatments?

Barrier offers dual-action internal and external parasite control, combining imidacloprid and moxidectin, unlike some single-agent products that may only target fleas or heartworms.

Trusted Medical References