Barrier Topical Solution for Dogs, 88.1-110 lbs, (Yellow)

Barrier Topical Solution for Dogs 88.1–110 lbs – 6 Doses (6-Month Supply)

Rx-Only | Contains Imidacloprid + Moxidectin

Barrier Topical Solution for Dogs 88.1–110 lbs is a monthly prescription medication designed to provide comprehensive parasite protection for large breed dogs weighing between 88.1 to 110 lbs. Formulated with Imidacloprid and Moxidectin, this veterinary-grade solution safeguards against heartworm disease, intestinal worms (roundworms, hookworms, whipworms), sarcoptic mange, and flea infestations.

Unlike over-the-counter flea preventatives, Barrier requires a prescription due to its broader parasitic coverage, including microfilariae of Dirofilaria immitis, the causative agent of canine heartworm.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Also Available in Other Dog Weight Ranges

Barrier for Dogs is formulated in multiple strengths to ensure precise and safe dosing for dogs of all sizes. Always choose the variant that matches your dog’s current weight for maximum efficacy and safety.

• Barrier for Dogs 3–9 lbs – Green: Perfect for toy breeds and small puppies over 7 weeks of age.
• Barrier for Dogs 9.1–20 lbs – Ice Blue: Designed for small to medium-sized dogs needing monthly parasite protection.
• Barrier for Dogs 20.1–55 lbs – Pink: Ideal for medium to large breeds prone to fleas and worms.
• Barrier for Dogs 55.1–88 lbs – Blue: Best suited for large breed dogs requiring broad-spectrum parasite coverage.

What Are the Benefits of Barrier for Dogs 88.1–110 lbs?

• Prevents heartworm disease caused by Dirofilaria immitis
• Kills adult fleas and prevents re-infestation
• Treats and controls intestinal parasites: hookworms, roundworms, whipworms
• Eliminates sarcoptic mange caused by Sarcoptes scabiei
• Once-monthly topical dosing
• Prescription-strength protection for multi-parasite control
• Easy-to-apply waterproof formula

How Does Barrier Work to Protect Your Dog?

Together, these ingredients work systemically and topically to neutralize external parasites like fleas and mange mites, and internal parasites like heartworms and GI worms.

Dosage and Administration

Always consult your veterinarian for exact dosage instructions depending on your pet's condition.

• Apply one 5.0 mL tube topically once every 30 days
• Part the hair at the base of the neck between the shoulder blades
• Apply the entire contents directly on the skin
• Do not massage in; allow to air dry
• Do not bathe or allow swimming for at least 4 hours after application

Note: Safe for dogs and puppies 8 weeks of age and older, weighing at least 88.1 lbs

What Parasites Does Barrier for Dogs Treat and Prevent?

Are There Any Side Effects of Barrier for Large Dogs?

Possible side effects may include:

• Mild skin irritation or hair loss at the application site
• Lethargy or decreased appetite
• Neurological signs (tremors, ataxia) in rare cases
• Vomiting or salivation

Seek veterinary attention immediately if your dog shows signs of toxicity, especially in dogs with pre-existing neurological disorders.

What Warnings Should I Follow When Using Barrier?

• For topical use only – do not administer orally
• Avoid contact with mouth or eyes
• Children should not touch treated animals until the product dries
• Not for use in sick, debilitated, or underweight dogs
• Do not use on cats – serious adverse reactions may occur
• Wash hands thoroughly after application

Keep out of reach of children and pets. Use only as directed by your veterinarian.

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Barrier Topical Solution for Dogs 88.1–110 lbs FAQs 

What is Barrier Topical Solution used for in dogs?

Barrier is a prescription topical treatment that prevents heartworm disease and treats fleas, intestinal worms, and mange in large dogs weighing 88.1–110 lbs.

Does Barrier kill internal parasites?

Yes. Moxidectin in Barrier treats and controls roundworms, hookworms, and whipworms commonly found in dogs.

Is Barrier the same as Advantage Multi?

Yes, Barrier contains the same active ingredients—Imidacloprid and Moxidectin—as Advantage Multi, offering similar spectrum protection.

How soon after applying Barrier can I bathe my dog?

Wait at least 4 hours after application before bathing or swimming to maintain effectiveness.

Can I use this product if my dog is on heartworm prevention already?

No. Barrier already contains heartworm prevention; do not double-dose. Always consult your vet before combining medications.

Trusted Medical References

• Imidacloprid – NPIC (National Pesticide Information Center):
• Dirofilaria immitis (Heartworm) – University of Saskatchewan (WCVM)
• Moxidectin – ScienceDirect
• Sarcoptic Mange – VCA Animal Hospitals