Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99

Monthly 6-in-1 Spot-On for Heartworm, Fleas and Parasites in Small Dogs
Product Description
Barrier Topical Solution (Teal/Ice Blue Box, 9.1 to 20 lbs) is an FDA-approved, prescription-only monthly spot-on for dogs and puppies 7 weeks or older weighing 9.1 to 20 lbs. Each 1.0 mL tube delivers 10% imidacloprid and 2.5% moxidectin, the same active ingredients as Advantage Multi for Dogs. One monthly dose prevents heartworm, treats microfilariae, kills adult fleas, treats intestinal worms, and controls sarcoptic mange in small dogs.
Benefits
- Prevents Heartworm Disease: Moxidectin prevents Dirofilaria immitis larval development into adult heartworms when applied once monthly to small dogs.
- Treats Circulating Microfilariae: Unlike many other preventives, Barrier for Dogs also treats existing Dirofilaria immitis circulating microfilariae in heartworm-positive dogs.
- Kills Adult Fleas: Imidacloprid kills adult fleas fast, providing effective flea treatment and preventing flea infestations with each monthly dose.
- Treats Intestinal Worms: Effectively treats and controls intestinal infections caused by hookworms, roundworms, and whipworms in small dogs.
- Treats Sarcoptic Mange: Treats and controls sarcoptic mange (Sarcoptes scabiei) infestations in small dogs with each monthly topical application.
- Single-Spot Application: The entire tube is applied in one spot between the shoulder blades, making monthly application quick and straightforward for small dogs.
- Same Ingredients, Better Value: Contains the same active ingredients as Advantage Multi for Dogs, offering equivalent six-in-one parasite protection.
- Made in the USA: Manufactured and packaged in the USA from a registered FDA facility, ensuring quality and regulatory compliance.
Ingredients
Composition Table
| Ingredient | Quantity |
| Imidacloprid | 10% (100 mg per 1.0 mL tube) |
| Moxidectin | 2.5% (25 mg per 1.0 mL tube) |
Other Ingredients
Benzyl alcohol, Propylene carbonate
How to Use
Directions for Use
- Prescription Required: Under US federal law, only a licensed veterinarian can prescribe or order the use of this medication.
- Dog Must Be Standing: Have your dog standing throughout the entire application process to ensure even solution distribution.
- Open the Tube Correctly: Hold the tube straight up, break the seal by twisting the cap, and apply with the cap still attached.
- Apply Between Shoulder Blades: Part the hair between the shoulder blades until skin is visible, then apply the entire tube contents in one spot.
- Squeeze Entire Contents: Apply directly onto the skin in one spot and allow the area to dry naturally without rubbing the product in.
- Lift Tube Before Releasing: Remove the tube from the skin before releasing pressure to prevent the solution from being drawn back in.
- Apply Once Monthly: Administer every 30 days for continuous heartworm prevention, flea control, and parasite protection throughout the year.
- Prevent Post-Application Licking: Keep the dog from licking the application site for 30 minutes and separate treated animals from other pets.
- Test for Heartworm First: Test all dogs for existing heartworm infection before starting Barrier; consult your veterinarian about adulticide treatment if needed.
Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.
Additional Information
Precautions
- Minimum Age and Weight: Avoid using this in dogs that are less than 7 weeks of age or below 3 lbs in weight.
- Never Use on Cats: This dog formulation contains 2.5% moxidectin, far higher than the cat formula, and can be fatal to cats.
- Do Not Give Orally: Never administer this product orally; ingestion may cause depression, salivation, dilated pupils, incoordination, panting, and muscle tremors.
- Avermectin-Sensitive Dogs: In MDR1-mutation dogs, accidental oral ingestion may cause severe reactions including coma and death; use with extreme caution.
- Sick or Debilitated Dogs: Use with caution in sick, debilitated, or underweight animals and always seek veterinary guidance before applying Barrier.
- Breeding, Pregnant, Lactating Dogs: Safety has not been established in breeding, pregnant, or lactating dogs; consult your veterinarian before use.
- Keep Children Away: Children should not come into contact with the application sites for two hours after applying the product.
- Eye Irritant for Humans: Should it enter the eyes, wash them with water for 15 minutes and make sure to thoroughly clean your hands with soap and water afterward.
Possible Side Effects
- Hematochezia and Diarrhea: Blood in stool and diarrhea have been reported in field studies; contact your veterinarian if these occur.
- Vomiting and Inappetence: Vomiting and reduced appetite have been reported following treatment in field safety studies with dogs.
- Lethargy and Pyoderma: Lethargy and skin infection at the application site have been reported in dogs during field studies.
- Neurological Signs: Weakness, depression, and unsteadiness have been reported in dogs after application; contact your veterinarian immediately if observed.
- Application Site Reactions: Localized itching and hyperkeratosis at the application site have been reported in dogs with pre-existing flea allergy dermatitis.
Storage Information
- Store at Cool Temperature: Store between 4°C (39°F) and 25°C (77°F); avoid exposure to excess heat or cold at all times.
- Secure Storage Required: Store this prescription product securely out of reach of children and other animals at all times.
Shipping & Return
We offer ground, express, and priority delivery; see our shipping policy for details.
For return instructions or product concerns, please refer to our detailed refund policy.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Frequently Asked Questions
Q1: What does Barrier Topical Solution (Teal/Ice Blue Box) treat and prevent in small dogs?
Ans: Barrier Teal/Ice Blue Box is a monthly 6-in-1 spot-on for dogs 9.1 to 20 lbs that prevents heartworm, treats circulating microfilariae, kills adult fleas, treats flea infestations, controls hookworms, roundworms, and whipworms, and treats sarcoptic mange in dogs and puppies 7 weeks or older.
Q2: Why is the Teal Box applied in one spot while larger dogs need multiple spots?
Ans: For dogs 20 lbs or less, the small volume absorbs effectively in one spot between the shoulder blades. For larger dogs, applying one spot causes pooling and reduces absorption, so 3 to 4 backline spots are required for complete coverage and optimal efficacy.
Q3: Can the small dog spot-on treat a heartworm-positive dog?
Ans: Yes. Barrier for Dogs is indicated for treating Dirofilaria immitis circulating microfilariae in heartworm-positive dogs. It does not eliminate adult heartworms, so veterinarians may also recommend adulticide treatment to remove existing adult worms alongside the microfilariae treatment protocol.
Q4: How does the Teal Box differ from the Green Box for extra-small dogs?
Ans: The Teal Box contains 1.0 mL delivering 100 mg imidacloprid and 25 mg moxidectin for dogs weighing 9.1 to 20 lbs. The Green Box contains 0.4 mL delivering 40 mg imidacloprid and 10 mg moxidectin for dogs 3 to 9 lbs. Both offer identical six-in-one protection.
Q5: Is the small dog monthly spot-on safe for pregnant or lactating dogs?
Ans: Barrier for Dogs has not been tested for safety in breeding dogs or those that are pregnant or nursing. If your small dog is pregnant, nursing, or intended for breeding, always consult your veterinarian before starting any parasite prevention program to determine the safest and most appropriate option.
Clinical Research
Imidacloprid – NPIC (National Pesticide Information Center)
Dirofilaria immitis (Heartworm) – University of Saskatchewan (WCVM)