Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
12-Week Flea and Tick Spot-On Protection for Large Dogs
Product Description
Bravecto Topical Solution (Blue Box) is an FDA-approved, prescription-only spot-on for dogs and puppies 6 months or older weighing 44 to 88 lbs. Each single-use tube holds 1000 mg of fluralaner, which absorbs through the skin into the bloodstream and gets to work when fleas and ticks feed on your dog. One application keeps fleas and three major tick species away for 12 weeks, and lone star ticks covered for 8 weeks.
Benefits
- 12-Week Flea Protection: Kills adult fleas and stops Ctenocephalides felis infestations from taking hold for a full 12 weeks from a single application.
- Fast-Acting Formula: Fleas start dying within 2 hours of application and ticks within 12 hours, so large dogs get noticeable relief quickly.
- Black-Legged Tick Control: A single dose keeps Ixodes scapularis black-legged tick infestations under control for 12 weeks.
- American and Brown Dog Tick Control: One application covers American dog ticks (Dermacentor variabilis) and brown dog ticks (Rhipicephalus sanguineus) for 12 weeks.
- Lone Star Tick Control: Amblyomma americanum lone star ticks are also covered, with each application keeping them controlled for 8 weeks from the dosing date.
- Water-Resistant After 3 Days: Bathing or swimming at least 3 days after applying does not affect protection against fleas and Ixodes ricinus ticks.
- Safe for MDR1 Dogs: Confirmed safe in dogs carrying the MDR1 gene mutation, which makes certain medications harder for some breeds to tolerate.
- No-Spill Applicator: The Twist'n'Use applicator requires no cap removal, making dosing simple and clean even for larger breeds.
Ingredients
Composition Table
| Ingredient | Quantity |
| Fluralaner | 1000 mg per tube |
Other Ingredients
Dimethylacetamide, Glycofurol, Diethyltoluamide, Acetone
How to Use
Directions for Use
- Prescription Required: Federal law limits this product to use by or on the order of a licensed veterinarian only.
- Minimum Dose: One application every 12 weeks delivers a minimum of 11.4 mg/lb (25 mg/kg) of body weight per dose.
- Wear Gloves: Wear gloves throughout the application and give your hands and any skin that came into contact with the product a thorough soap and water wash once you are done.
- Open the Tube Correctly: Hold the tube upright with the cap tip pointing up, then give the cap one full turn to break the seal; the cap remains on throughout the application.
- Position Your Dog: Your dog should be standing or lying flat with their back level before you begin.
- Apply Along the Back: Part the coat between the shoulder blades, press the tube tip directly onto the skin, and work the solution across several spots along the backline.
- Avoid Run-Off: Spread the solution across multiple spots rather than squeezing it all into one area, which is especially important for large dogs to prevent run-off.
- Lone Star Tick Exposure: Dogs regularly in contact with lone star ticks can be dosed every 8 weeks rather than every 12 weeks.
- Open Pouch Just Before Use: Only take the tube out of its sealed foil pouch at the time of application to protect the solution from moisture damage.
Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.
Additional Information
Precautions
- Minimum Age and Weight: Only suitable for dogs and puppies that have reached 6 months of age and weigh at least 4.4 lbs.
- Seizure History: Extra caution is needed for dogs with a seizure or neurological history; seizures have also been reported in dogs with no prior history.
- Topical Use Only: For external skin use only; never give orally and prevent your dog from licking the treated area.
- Breeding and Pregnant Dogs: Adverse events have been reported after use in breeding females; speak to your vet before applying to breeding, pregnant, or nursing dogs.
- Lone Star Tick Limit: Coverage against lone star ticks does not extend beyond 8 weeks; shorten the dosing interval if your dog is regularly exposed to this species.
- Keep Children Away: Allow at least 2 hours to pass before letting children near the area where the product was applied.
- Dogs Only: Never apply the dog formulation to cats; dog products used on cats can cause serious adverse reactions.
- Highly Flammable: Store and handle the tube well away from heat sources, open flames, sparks, and any other ignition risk.
Possible Side Effects
- Vomiting and Diarrhea: Digestive upset including vomiting and loose stools are among the most frequently reported reactions after treatment.
- Hair Loss and Skin Reactions: Hair loss at the treated spot, moist dermatitis, rash, redness, flaking, and scabbing have been reported following use.
- Lethargy and Decreased Appetite: A drop in energy levels and reduced interest in food have been noted in some dogs after dosing.
- Neurological Reactions: Seizures, tremors, and loss of coordination have been reported in rare cases; get in touch with your vet straight away if any of these appear.
- Greasy Application Site: A greasy, matted, or wet-looking area at the treated spot is a common cosmetic effect and not a reason for concern.
Storage Information
- Store Below 77°F: Do not store above 25°C (77°F) and keep away from direct sunlight and excessive heat.
- Keep in Original Packaging: The tube should stay sealed in its foil pouch and only be taken out at the time of application to protect it from moisture.
- Keep Away from Children: Store this prescription product somewhere children and other pets cannot reach it.
Shipping & Return
We offer ground, express, and priority delivery; see our shipping policy for details.
For return instructions or product concerns, please refer to our detailed refund policy.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Frequently Asked Questions
Q1: What does Bravecto Topical Solution (Blue Box) treat and prevent in large dogs?
Ans: Bravecto Blue Box kills adult fleas and prevents flea infestations for 12 weeks from one dose. It also controls black-legged ticks, American dog ticks, and brown dog ticks for 12 weeks, and lone star ticks for 8 weeks. It is designed for dogs weighing 44 to 88 lbs dosed once every 12 weeks.
Q2: How does the Blue Box differ from the Green Box?
Ans: The Blue Box holds 1000 mg of fluralaner for large dogs in the 44 to 88 lb range, while the Green Box contains 500 mg for medium dogs up to 44 lbs. Both deliver the same 12-week flea and tick coverage. Always choose the tube that reflects your dog's current weight for accurate dosing.
Q3: How does Bravecto Topical work in large dogs?
Ans: Once applied, fluralaner absorbs through the skin and spreads through the bloodstream. When fleas or ticks bite and feed, they take in fluralaner, which shuts down their nervous system by blocking chloride channels, leading to paralysis and death. This systemic protection holds for a full 12 weeks.
Q4: Is Bravecto Topical water-resistant for large dogs that swim or bathe frequently?
Ans: Yes. Bathing or swimming at least 3 days after applying does not reduce protection against fleas and Ixodes ricinus ticks. Waiting 3 days before the first wash after dosing is all that is needed, which is a practical advantage for active large-breed dogs that spend time outdoors or in water.
Q5: Is Bravecto Topical safe for breeding or pregnant large dogs?
Ans: Adverse events have been reported in breeding females after use. Safety in breeding, pregnant, and lactating dogs was assessed using the oral formulation. Always consult your veterinarian before applying Bravecto Topical to any large dog that is pregnant, nursing, or being used for breeding purposes.