Cardalis 80mg/10mg Chewable Tablets

Advanced Heart Failure Support for Dogs

Product Description

Cardalis 80 mg and 10 mg chewable tablets help control the symptoms of congestive heart failure in dogs caused by heart valve disease. This tablet is given once a day and contains spironolactone and benazepril, which work together to support heart health in different ways. It is often given together with other heart medications, such as furosemide, to provide well rounded support for your dog’s condition.

Benefits

• Dual RAAS Action: Combines spironolactone and benazepril to block aldosterone and ACE pathways for comprehensive RAAS inhibition.
• Proven Clinical Effectiveness: Demonstrated significantly lower treatment failure rates compared to benazepril alone in a 360-day field study.
• Once Daily Dosing: Administered orally once daily with food using scored tablets for accurate weight-based dosing.
• High Palatability: Voluntarily accepted in 87.6 percent of doses during controlled field study evaluation.
• Concurrent Therapy Compatible: Safely administered with furosemide, digoxin, calcium channel blockers, vaccines, and other common treatments.

Variants

• 20 mg spironolactone and 2.5 mg benazepril hydrochloride
• 40 mg spironolactone and 5 mg benazepril hydrochloride
• 80 mg spironolactone and 10 mg benazepril hydrochloride

Ingredients

Composition Table

How to Use

Dosage & Administration Instructions

• Stabilize First: Begin administration only after pulmonary edema has been stabilized in affected dogs.
• Weight-Based Dosing: Recommended dosage is 2 mg/kg spironolactone and 0.25 mg/kg benazepril hydrochloride administered once daily.
• Once Daily Dose: Administer orally once daily at 2 mg/kg spironolactone and 0.25 mg/kg benazepril hydrochloride.
• Give With Food: Provide tablets with food to ensure consistent absorption and therapeutic effectiveness.
• Accurate Splitting: Use whole or half-scored tablets to match the calculated dose to the nearest half tablet.
• Prescription Only: Federal law restricts this medication to use by or on the order of a licensed veterinarian.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Monitor Renal Function: Evaluate renal parameters and serum potassium before starting and during treatment.
• Avoid NSAID Use: Do not combine with NSAIDs in dogs with renal insufficiency.
• Digoxin Interaction: Monitor closely when used with digoxin due to increased risk of toxicity.
• Hepatic Caution: Use carefully in dogs with hepatic dysfunction due to extensive hepatic metabolism.
• Growing Dogs Warning: Safety not evaluated in growing dogs, and spironolactone has antiandrogenic effects.
• Breeding Safety Unknown: Safety not established in pregnant, lactating, or breeding dogs.

Possible Side Effects

• Digestive Upset: May cause anorexia, vomiting, or diarrhea during treatment.
• Lethargy Signs: Lethargy was reported in treated dogs during a clinical field study.
• Renal Changes: Renal insufficiency was reported more frequently in treated dogs.
• Electrolyte Elevation: Serum potassium and magnesium levels may increase during therapy.
• Urinary Issues: Urinary incontinence was observed in a portion of treated dogs.

Storage Information

• Store at Room Temperature: Keep the tablets in a room that stays between 20°C and 25°C.
• Short-Term Temperature Changes: It is fine if the temperature briefly falls between 15°C and 30°C.
• Keep in Original Bottle: Always store the tablets in their original container to help maintain their quality.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is Cardalis 80 mg and 10 mg used for in dogs?

Ans: Cardalis helps control the symptoms of congestive heart failure in dogs, whether the condition is mild, moderate, or severe, and caused by a faulty heart valve. It is usually given with other heart medications, such as furosemide, and treatment should begin after fluid in the lungs has been stabilized.

Q2: How does Cardalis work to support heart function in dogs?

Ans: Cardalis contains spironolactone and benazepril, which work on the renin angiotensin aldosterone system in different ways. Spironolactone blocks the effects of aldosterone, while benazepril blocks ACE. This helps relax blood vessels and lower aldosterone levels, giving more complete control of the RAAS system.

Q3: How should Cardalis 80 mg and 10 mg be administered?

Ans: Cardalis should be given orally once daily at 2 mg/kg spironolactone and 0.25 mg/kg benazepril hydrochloride. Tablets must be administered with food and dosed to the nearest half tablet using the scored format.

Q4: Is Cardalis safe to use with other heart medications?

Ans: In field studies, Cardalis was safely used alongside furosemide, digoxin, calcium channel blockers, vaccines, parasite treatments, and other common medications. However, dogs taking digoxin should be monitored closely, as Cardalis may increase digoxin levels in the blood.

Q5: What side effects can occur with Cardalis in dogs?

Ans: Some dogs experienced side effects such as reduced appetite, vomiting, diarrhea, tiredness, kidney issues, loss of bladder control, and higher potassium levels. There was one reported case of high potassium. It is important to routinely check kidney function and monitor potassium levels during treatment.