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Broad-Spectrum Injectable Antibiotic – Ceftriaxone for Veterinary Use
Ceftriaxone Injection, USP for Animals is a broad-spectrum prescription drug antibiotic prescribed to treat a wide range of bacterial infections in companion animals and livestock. Ceftriaxone Injection, USP for Animals is comprised of ceftriaxone sodium, a third-generation cephalosporin antibacterial against gram-positive and gram-negative bacteria. It is a sterile injectable solution to be injected intramuscularly (IM) or intravenously (IV) as recommended by veterinary experts. Ceftriaxone is widely utilized in the treatment of respiratory infections, urinary tract infections, soft tissue infections, and sepsis in dogs, cats, cattle, and other animals.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
NOTE: For generic medications, the picture displayed may not depict the actual product. Generic medications may vary from one order to the next by size, color, and shape, depending on the manufacturer. Please note product may arrive in a Hardy Paw Pharmacy vial.
Benefits:
- Wide-Spectrum Antimicrobial Spectrum: Ineffective against a broad range of disease-causing bacteria like E. coli, Staphylococcus spp., and Pasteurella.
- Extended-Interval Dosing Form: Offers extended intervals between doses due to increased half-life, which reduces animal handling stress.
- Versatile Administration: Suitable for application in multiple species—dogs, cats, cattle, and other veterinary clients.
- Sterile Injectable Form: Offers immediate bioavailability and precise dosing through IM or IV administration.
- Cephalosporin Class: A dependable choice for resistant, serious infections that cannot be treated with first-line antibiotics.
What does it treat in animals?
It is commonly administered for respiratory tract infection, urinary tract infection, skin and soft tissue infection, bone infection, and systemic bacterial infection, such as sepsis. By Excerpts from a Veterinary Authority.
Is Ceftriaxone for All Animals Safe?
It is a drug that is very well tolerated by animals but should always be given in the veterinary setting. It is decided on the dosage and frequency according to species, size, and severity of the infection. It is generally avoided in very young or lactating animals unless specifically allowed by a veterinarian.
Directions:
Intramuscular Administration:
Reconstitute ceftriaxone for injection powder with the appropriate diluent (see COMPATIBILITY AND STABILITY).
Inject diluent into the vial, and shake the vial thoroughly to form a solution. Withdraw the entire contents of the vial into the syringe to equal the total labeled dose.
After reconstitution, each 1 mL of solution contains approximately 250 mg or 350 mg equivalent of ceftriaxone according to the amount of diluent indicated below. If required, more dilute solutions could be utilized.
As with all intramuscular preparations, ceftriaxone for injection should be injected well within the body of a relatively large muscle; aspiration helps to avoid unintentional injection into a blood vessel.
| Vial Dosage Size | Amount of Diluent to be Added | |
|---|---|---|
| 250 mg/mL | 250 mg/mL | |
| 250 mg | 0.9 mL | -- |
| 500 mg | 1.8 mL | 1.0 mL |
| 1 g | 3.6 mL | 2.1 mL |
| 2 g | 7.2 mL | 4.2 mL |
Intravenous Administration:
Ceftriaxone for injection should be administered intravenously by infusion over 30 minutes, except in neonates, where administration over 60 minutes is recommended to reduce the risk of bilirubin encephalopathy. Concentrations between 10 mg/mL and 40 mg/mL are recommended; however, lower concentrations may be used if desired. Reconstitute vials with an appropriate IV diluent (see COMPATIBILITY AND STABILITY).
| Vial Dosage Size | Amount of Diluent to be Added |
|---|---|
| 250 mg | 2.4 mL |
| 500 mg | 4.8 mL |
| 1 g | 9.6 mL |
| 2 g | 19.2 mL |
After reconstitution, each 1 mL of solution contains approximately 100 mg equivalent of ceftriaxone. Withdraw the entire contents and dilute to the desired concentration with the appropriate IV diluent.
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FAQ
What kinds of uses does ceftriaxone injection, USP offer or allow access to within animal subjects?
It is an injectable broad-spectrum, third-generation cephalosporin antibiotic, which is used to treat serious bacterial infections in animals or dogs, especially in most cases in the hospital setting.
What types of infections does it work against?
Ceftriaxone is meant to treat any respiratory illness or skin infection, urinary tract infections, septicemia, as well as infections in bones and joints.
For which animals is this injection applied?
Regularly used in dogs and cats, and alien at times in exotic or farm animals, but always under veterinary supervision, it is not FDA approved in any species.
What routes of administration does Ceftriaxone have?
It is usually administered IM or IV, mostly in a veterinary office. The dose and route will differ according to the veterinarian.
Is it a prescription medication or an over-the-counter drug?
Ceftriaxone Injection, USP is a prescription drug and should be administered under the direction of a licensed veterinarian.
How frequently should this injection be administered?
Dosage frequency will vary based on clinical indication, animal size, and severity, although typically it is a once-daily dose as directed by the vet.