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Comfortis Chewable Tablet for Dogs & Cats

$19.73

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Prescription Required

Elanco SKU: CA4222Y07AM-1

Pet Weight: Dogs 5-10 lbs & Cats 4.1-6 lbs
Quantity: 1 Chewable Tablet
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Vet-Prescribed Flea Tablets for Monthly Defense

Product Description

Comfortis Chewable Tablets are fast-acting, veterinarian-prescribed tablets designed to kill fleas and stop infestations for a full month. These tablets protect against fleas for dogs and cats 14 weeks and older. Their easy-to-administer chewable form ensures stress-free dosing, helping to keep pets comfortable, itch-free, and protected from flea infestations. 

Benefits

  • Fast flea action: Starts killing fleas quickly and provides full month protection after a single dose.
  • Easy administration: Flavored tablets can be mixed with food for easy oral intake.
  • Vet-recommended treatment: Prescribed by veterinarians and FDA-approved for flea infestations.
  • Suitable for dogs: Safe for use in dogs 14 weeks of age or older with proper dosage.
  • One-month protection: One tablet provides protection against fleas for up to 30 days.

Variants

Variants Dog Weight (lbs) Cat Weight (lbs)
1 5 – 10 4.1 – 6
2 10.1 – 20 6.1 – 12
3 20.1 – 40 12.1 – 24
4 40.1 – 60
5 60.1 – 120

Ingredients

140 mg Spinosad.

How to Use

Recommended-Dosage Chart

For Dogs 

Body Weight (lbs) Spinosad per Tablet (mg)
5 – 10 140 mg 
10.1 – 20 270 mg 
20.1 – 40 560 mg
40.1 – 60 810 mg
60.1 – 120 1620 mg

*For dogs weighing more than 120 lbs, use a suitable combination of tablets to achieve the correct dosage. 

For Cats 

Body Weight (lbs) Spinosad per Tablet (mg)
4.1 – 6 140 mg
6.1 – 12 270 mg
12.1 – 24 560 mg

*For cats weighing more than 24 lbs, give a proper combination of tablets to ensure the correct dosage. 

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet. 

Dosage & Administration Instructions

Monthly Oral Dosage 

For Dogs 

  • Comfortis should be administered orally to dogs once a month at a recommended minimum dose of 13.5 mg per pound (30 mg/kg) of body weight.

For Cats 

  • Comfortis should be given orally once every month at a recommended minimum dosage of 22.5 mg per pound (50 mg/kg) body weight to provide complete flea prevention and control for cats. 

Additional Information

Precautions

For Dogs 

  • Appropriate Age for Use: Comfortis is recommended only for dogs and puppies aged 14 weeks or older for safety.
  • Use in Breeding or Nursing Dogs: Administer Comfortis cautiously in breeding or nursing females and consult a veterinarian for proper evaluation.
  • Dogs with Health Conditions: Use with caution in dogs that have a history of seizures or neurological conditions to prevent risk.
  • Veterinary Advice Before Combining Treatments: Always seek professional veterinary advice before combining Comfortis with other prescribed or over-the-counter medications.

For Cats 

  • Careful Use with Ivermectin: Use Comfortis cautiously when given alongside ivermectin used off-label, as combined use may increase adverse reactions.
  • Veterinary Consultation Recommended: Before using Comfortis with other medications, consult your veterinarian to ensure safe and effective administration for your cat.
  • Monitor for Unusual Reactions: Observe your cat closely after administration for any signs of discomfort, sensitivity, or adverse drug interactions.

Possible Side Effects

For Dogs 

  • Vomiting: Vomiting was the most frequently reported reaction, typically occurring within 48 hours after Comfortis administration in dogs.
  • Decreased Appetite: Some dogs experienced a reduced appetite temporarily, usually mild and resolving without the need for medical treatment.
  • Lethargy: A small percentage of dogs showed mild lethargy or fatigue after treatment, which generally resolved within days.
  • Diarrhea: Instances of diarrhea were observed in a few dogs, usually mild and self-limiting without long-term effects.
  • Cough or Polyphagia: Occasional coughing or increased hunger (polyphagia) was reported but not considered serious or treatment-related.
  • Increased Appetite or Hyperactivity: Some dogs displayed an increased appetite or mild hyperactivity, both of which were short-term and non-severe.
  • Redness or Itching (Erythema/Pruritus): A few dogs experienced temporary skin redness or itching, which subsided without additional medical intervention.
  • Excessive Salivation: Rare cases of mild drooling or excessive salivation occurred, generally resolving within a few hours post-dosing. 

For Cats 

  • Vomiting: The most common side effect observed was vomiting, occurring in up to 14.8% of treated cats.
  • Lethargy: Some cats experienced mild lethargy or decreased activity shortly after treatment, typically resolving within a short period.
  • Anorexia: A few cats showed temporary loss of appetite following administration, which generally improved without further intervention.
  • Weight Loss: Mild, short-term weight loss was occasionally reported in some cats during the 90-day observation period.
  • Diarrhea: A small percentage of cats experience diarrhea, which is usually mild and self-limiting, requiring no additional treatment.
  • Frequency of Vomiting: Vomiting most often occurred on the day of or the day after Comfortis administration in cats. 

Storage Instructions 

 

  • Storage: Store product between 68°–77°F; temporary variations between 59°–86°F are allowed safely. 

 

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is Comfortis, and how does it work for pets?

Ans: Comfortis (spinosad) is a veterinarian-prescribed chewable tablet for dogs and cats designed to rapidly kill fleas and provide full-month protection. Administered orally, it keeps pets comfortable, itch-free, and protected from infestations with a single dose.

Q2: How should Comfortis be administered to dogs and cats?

Ans: Comfortis is given orally once every month at the recommended dosage based on the pet’s weight. Dogs require 13.5 mg per pound and cats 22.5 mg per pound, ensuring effective flea prevention and control while minimizing stress during dosing.

Q3: What age is appropriate for Comfortis use?

Ans: Comfortis is safe for dogs and cats 14 weeks and older. Puppies and kittens younger than this age should not receive the medication. Always consult a veterinarian before starting treatment in younger pets or those with special health conditions.

Q4: Can Comfortis be combined with other medications?

Ans: Before combining Comfortis with any other prescription or over-the-counter medications, consult a veterinarian. This ensures safe administration, avoids possible adverse drug interactions, and prevents complications, particularly for pets with neurological conditions or existing health concerns.

Q5: What are the possible side effects in dogs?

Ans: Dogs may experience mild vomiting, temporary decreased appetite, lethargy, diarrhea, coughing, or excessive salivation. Most effects are short-term and self-resolving. Skin redness, itching, increased appetite, or mild hyperactivity may also occur but are generally non-serious.

Q6: What side effects should cat owners monitor for?

Ans: Cats may show vomiting, mild lethargy, temporary anorexia, slight weight loss, or diarrhea. Vomiting typically occurs the day of or after administration. Most reactions are mild, short-lived, and resolve without additional treatment. Veterinary consultation is advised for any concerns.