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Dantrolene Capsules, 100mg

Varies (Generic) SKU: 273507-1

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$1.45

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Size: 1 capsule
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Muscle Relaxant Capsules for Spasms and Hyperthermia in Pets and Horses

Product Description

Dantrolene Sodium 100mg Capsules are a prescription skeletal muscle relaxant used by veterinarians for dogs, cats, and horses. It works by stopping calcium from being released inside skeletal muscle cells, which settles down abnormal contractions and eases muscle spasm. It is used for functional urethral obstruction in dogs and cats, malignant hyperthermia during anesthesia, canine stress syndrome, and exertional rhabdomyolysis and post-anesthetic myositis in horses, and is prescribed off-label across all veterinary species.

Benefits

  • Urethral Obstruction Relief: Eases urethral muscle spasm in dogs and cats, helping normal urine flow return and taking the discomfort down with it.
  • Malignant Hyperthermia Treatment: No other medication can address malignant hyperthermia, a rare and potentially fatal anesthetic reaction seen in pets.
  • Equine Rhabdomyolysis Prevention: Helps prevent and treat exertional rhabdomyolysis in horses by settling calcium-driven muscle contractions during and after exercise.
  • Post-Anesthetic Myositis Support: Lowers the risk and severity of post-anesthetic myositis in horses coming out of general anesthesia procedures.
  • No Cardiac or Smooth Muscle Effect: Works specifically on skeletal muscle without touching cardiac or smooth muscle function, making it a more targeted relaxant overall.

Ingredients

Active Ingredients

Dantrolene Sodium

How to Use

Dantrolene Sodium 100mg Capsules are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.

Please follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.

Disclaimer: Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.

Tucking this capsule into a soft pill pocket or pill wrap treat is a practical way to get your pet to take their dose without any fuss. Pairing it with food is also a good idea, since it can help keep any stomach discomfort at bay during treatment.

Shop Pill Pockets for Dogs | Shop Pill Pockets for Cats

Additional Information

Precautions

  • Avoid in Liver Disease: Pets with reduced liver function should not be given this medication, as the liver processes it and serious toxicity can develop.
  • Avoid in Cardiac and Pulmonary Disease: Pets with significant heart or lung disease need very careful assessment before this medication is considered, or it may need to be avoided entirely.
  • Avoid Calcium Channel Blockers: This medication should not be given alongside calcium channel blockers like amlodipine, as there have been rare reports of fatal cardiac collapse with this combination.
  • Caution in Pregnancy: This medication is not recommended for pregnant or lactating animals unless a veterinarian has reviewed the situation and confirmed it is needed.
  • CNS Depression Risk: Using this medication alongside benzodiazepines or other tranquilizers may add to central nervous system depression in pets.
  • Baseline Bloodwork Required: A veterinarian will often check liver values and potassium levels before starting and at regular points throughout the treatment period.

Possible Side Effects

  • Sedation and Weakness: Drowsiness, muscle weakness, and general tiredness are among the more commonly seen reactions in dogs and cats on dantrolene.
  • Digestive Upset: Vomiting, diarrhea, and a drop in appetite can come up during treatment and often ease when the medication is given alongside food.
  • Liver Toxicity: The liver can be affected by this medication, particularly with longer use, so periodic liver monitoring is an important part of ongoing care.
  • Low Blood Pressure: A drop in blood pressure has been noted in some pets and can show up as weakness or collapse that needs prompt veterinary attention.
  • Delayed Allergic Sensitivity: Sensitivity to this medication can build up over time, so keeping an eye out for allergic reactions throughout the full course of treatment is important.

Storage Information

  • Room Temperature: Capsules do best at room temperature inside a tightly closed container, away from heat, moisture, and direct light.
  • Protect From Light and Moisture: Humid conditions and sunlight can wear down the capsule's potency, so a dry, shaded storage spot is the right choice.
  • Out of Reach: Keep this medication somewhere children and untreated animals in the home cannot get to it.

NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What conditions does dantrolene treat in dogs, cats, and horses?

Ans: Dantrolene is used for functional urethral obstruction, malignant hyperthermia during anesthesia, and canine stress syndrome in dogs and cats. In horses, it covers exertional rhabdomyolysis and post-anesthetic myositis. A veterinarian will assess whether it is the right option for your animal's specific condition.

Q2: Is dantrolene the only treatment for malignant hyperthermia in pets?

Ans: Dantrolene stands as the only medication that can address malignant hyperthermia, a rare but potentially fatal reaction that can develop under general anesthesia. It works by preventing the surge of calcium inside muscle cells that sets off the dangerous and uncontrolled contractions seen with this condition.

Q3: Why is liver monitoring important during dantrolene treatment in pets?

Ans: Since the liver handles the breakdown of this medication, prolonged use can put strain on liver function and lead to hepatotoxicity. A veterinarian will usually run liver enzyme checks before starting and at regular intervals during treatment. Yellowing of the eyes, ongoing vomiting, or a complete loss of appetite should be flagged right away.

Q4: Can dantrolene be given to pets with heart disease?

Ans: Pets with significant cardiac or pulmonary disease need very careful evaluation before being put on this medication, and it may need to be avoided entirely. Combining it with calcium channel blockers like amlodipine is also off the table, as there are documented cases of fatal cardiac collapse when the two are used together.

Q5: How quickly does dantrolene work in dogs and cats?

Ans: Dantrolene is short-acting and typically clears from the system within 24 hours of the last dose, though this may stretch longer in pets with kidney or liver conditions. For urgent situations like malignant hyperthermia, the intravenous form is used for speed. The oral capsule is reserved for non-emergency and preventive use.

Clinical Research

Animal type: Dogs, Cats, Horses

Dog age group: Adult, Senior

Pet supply product form: Capsules