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Hydralazine Tablets, 25mg

Varies (Generic) SKU: 261290-1

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Size: 1 tablet
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Hydralazine Tablets for Hypertension and Heart Failure in Pets

Product Description

Hydralazine 25 mg Tablets are a prescription-only arteriolar vasodilator used off-label in dogs and cats for hypertension and congestive heart failure. Relaxing the smooth muscle walls of arterioles widens blood vessels, lowers pressure, and eases the workload on the heart. Not FDA-approved for veterinary use, it is widely and legally prescribed off-label by licensed veterinarians.

Benefits

  • Reduces Blood Pressure: Relaxes arterial smooth muscle to widen blood vessels, bringing systemic blood pressure down effectively in dogs and cats.
  • Supports Heart Failure: Reduces cardiac afterload in dogs with congestive heart failure, easing the strain on the heart with every beat.
  • Refractory CHF Management: Used when standard ACE inhibitors and pimobendan no longer give adequate control in dogs with advanced heart failure.
  • Mitral Valve Support: A useful option for dogs with heart failure tied to degenerative mitral valve disease causing high arterial resistance.
  • Hypertensive Crisis Use: Addresses acute and chronic systemic hypertension in dogs and cats, including urgent hypertensive crisis situations under veterinary care.

Ingredients

Active Ingredient

Ingredient Strength per Tablet
Hydralazine Hydrochloride (Active) 25 mg

How to Use

Dosage & Administration Instructions

Hydralazine 25 mg Tablets are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.

Please follow your veterinarian's instructions carefully for the dosage and administration of this medication.

Disclaimer: Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.

Tucking a tablet inside a soft Pill Pocket or wrapping it in a small piece of your pet's favorite treat is a simple and caring way to make each dose easier for both of you. A pill pocket treat takes the stress out of medicating your pet and helps ensure no dose is missed. Shop Pill Pockets for Dogs | Shop Pill Pockets for Cats

Additional Information

Precautions

  • Low Blood Pressure: Not for pets with existing hypotension; this product will drive already dangerous blood pressure levels down even further.
  • Intracerebral Bleeding: Extra caution is needed in pets with intracerebral bleeding, as blood pressure shifts may aggravate the underlying condition.
  • Sodium and Water Retention: Fluid and sodium build-up may develop; a diuretic is often prescribed alongside this product to counteract the effect.
  • Reflex Tachycardia Risk: Beta-blockers are sometimes added to offset the reflex fast heart rate this product commonly triggers in treated pets.
  • Pregnancy Caution: Not suitable for pregnant animals; tell your veterinarian if your pet is pregnant before this product is started.
  • Drug Interactions: ACE inhibitors, beta-blockers, calcium channel blockers, diuretics, and anaesthetics may all interact significantly with this product in treated pets.
  • Renal Impairment Risk: This product's pressure-lowering effect can reduce kidney perfusion in pets with renal disease; use with extra care throughout.
  • Regular Monitoring Needed: Blood pressure, kidney function, and cardiac status must be checked regularly throughout the full course of treatment.
  • Prescription Only: Not FDA-approved for veterinary use; a licensed veterinarian must directly order this product before it can be dispensed.

Possible Side Effects

  • Severe Hypotension: A dangerous pressure drop is the key risk; doses begin low and rise gradually under close veterinary oversight.
  • Reflex Tachycardia: Falling blood pressure from this product can trigger a reactive rise in heart rate in some treated pets.
  • Vomiting and Anorexia: Nausea, vomiting, and reduced appetite are commonly reported, particularly in cats receiving this product for blood pressure control.
  • Lethargy and Weakness: Reduced energy and physical weakness may appear in treated pets, often linked to this product's blood pressure-lowering action.
  • Fluid Retention: Fluid and sodium may accumulate, leading to swelling or heavier fluid build-up in pets already managing heart failure.
  • Eye Inflammation: Conjunctivitis has been recorded as a possible reaction in some pets receiving this product during their treatment course.

Storage Information

  • Room Temperature Storage: Find a dry indoor spot between 68°F (20°C) & 77°F (25°C) and keep this product there consistently.
  • Protect from Light: Keeping the container tightly closed and clear of direct light is what these tablets need to stay effective.
  • Keep Out of Reach: Lock this product away or store it somewhere children and other household animals simply cannot get into.

NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is Hydralazine 25 mg used for in dogs and cats?

Ans: Used off-label in dogs and cats to manage systemic hypertension and congestive heart failure, this product relaxes arterial walls to lower pressure and ease cardiac workload. It tends to be reached for when standard heart medications are no longer holding up well enough.

Q2: Is Hydralazine a first-line blood pressure medication for pets?

Ans: No, this is not a first-choice antihypertensive for pets. It is held back for hypertensive crises and advanced heart failure where ACE inhibitors and pimobendan have stopped working adequately. Your vet will decide if it is the right fit for your pet.

Q3: Why does Hydralazine need to be started at a low dose?

Ans: The gap between a helpful dose and a harmful one is narrow with this product. Starting low and moving up slowly lets vets keep a close eye on blood pressure and steer clear of sudden drops causing weakness or fainting.

Q4: What should I monitor at home while my pet takes Hydralazine?

Ans: Watch for weakness, low energy, or fainting pointing to low blood pressure, and vomiting or poor appetite as digestive signs. Report anything unusual to your vet straight away. Blood pressure checks and kidney function tests are typically part of the ongoing monitoring plan.

Q5: Does Hydralazine interact with other heart medications in pets?

Ans: Yes. ACE inhibitors, beta-blockers, calcium channel blockers, diuretics, corticosteroids, and anaesthetics all have the potential to interact with this product. Give your vet a full and current list of every medication, supplement, and herbal remedy your pet is on before treatment begins.

Animal type: Dogs, Cats

Dog age group: Adult, Senior

Pet supply product form: Tablets