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K9 Advantix II for Extra Large Dogs (over 55 lbs) Blue Box

$57.48

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Bayer SKU: 86315017 Barcode: 742408920305

Size: 4 Doses (4 mos. supply)

K9 Advantix II for Extra Large Dogs (Over 55 lbs)

Fast-Acting Flea & Tick Treatment by HardyPaw

K9 Advantix II for Extra Large Dogs is a veterinarian-recommended, topical flea and tick treatment specifically formulated for dogs weighing over 55 lbs. This powerful multi-parasitic repellent and killer offers broad-spectrum protection against fleas, ticks, mosquitoes, biting flies, and lice—without requiring a bite to take action.

Formulated with Imidacloprid, Permethrin, and Pyriproxyfen, K9 Advantix II provides dual-action protection by both repelling and killing pests on contact. This monthly, waterproof application is ideal for dogs living in high-risk outdoor environments, offering consistent protection across varying climates and parasite populations.

What Are the Key Benefits of K9 Advantix II for Extra Large Dogs?

  • Fast Action, Long-Lasting Protection: Kills fleas within 12 hours of application and prevents reinfestation for up to 30 days.
  • Repels & Kills Multiple Parasites: Deters fleas, ticks (including deer ticks), mosquitoes, biting flies, and chewing lice.
  • Stops Flea Life Cycle: Pyriproxyfen (an insect growth regulator) disrupts flea egg and larval development to prevent future outbreaks.
  • Waterproof Formula: Remains effective even after bathing or swimming.
  • Non-Systemic Topical Application: Begins working through direct contact—no need for the parasite to bite.
  • Veterinarian-Recommended for XL Breeds: Tailored for large and giant breed dogs weighing 55 lbs and above.

What Breeds is K9 Advantix II XL Ideal For?

This treatment is ideal for extra-large breeds over 55 lbs, including but not limited to:

  • German Shepherds
  • Golden Retrievers
  • Labrador Retrievers
  • Great Danes
  • Bernese Mountain Dogs
  • Mastiffs
  • Rottweilers
  • Saint Bernards
  • Newfoundlands
  • Alaskan Malamutes

It’s also perfect for working dogs and outdoor-active breeds exposed to pests in forests, parks, or rural areas.

How to Use K9 Advantix II for XL Dogs (Over 55 lbs)?

  • Use one pre-measured applicator per month.
  • Part your dog’s hair at multiple points between the shoulder blades and along the back.
  • Apply entire contents directly onto skin in spots to avoid runoff.
  • Avoid touching the application area until dry.

Important: Do not use on cats—contains Permethrin which is toxic to felines.

What Are the Active Ingredients in K9 Advantix II for Extra Large Dogs?

Ingredient

Function

Imidacloprid (8.8%)

Kills adult fleas via nervous system disruption

Permethrin (44.0%)

Repels and kills ticks, fleas, and mosquitoes

Pyriproxyfen (0.44%)

Prevents flea egg and larval development

These ingredients act synergistically to interrupt the flea lifecycle, repel harmful vectors like mosquitoes, and reduce the risk of vector-borne diseases like Lyme disease and ehrlichiosis.

Are There Any Side Effects of K9 Advantix II for Extra Large Dogs?

While generally safe, some dogs may experience:

  • Mild skin irritation or redness at the application site
  • Temporary lethargy or sensitivity
  • Excessive grooming or scratching

Discontinue use and consult your vet if adverse reactions persist or worsen.

What Warnings Should I Know Before Using This Product?

  • Not for use on cats – toxic if ingested or absorbed.
  • Do not use on puppies under 7 weeks of age.
  • Wash hands thoroughly after application.
  • Avoid contact with your dog’s eyes or mouth.
  • Keep out of reach of children and other pets until dry.

Dosage and Administration

Always consult your veterinarian for exact dosage instructions depending on your pet's condition.

Dog Weight

Product

Frequency

Over 55 lbs

K9 Advantix II XL

Once monthly

Environmental Protection & Pet Safety

At HardyPaw, we care about your pet and the planet.

  • Eco-Conscious Packaging: Made with recyclable materials.
  • Non-Systemic Formula: Minimizes chemical load in your dog’s bloodstream.
  • Ethical Testing: Only tested under veterinary supervision—no unnecessary animal testing.

Expert Tips for Better Flea & Tick Control

  1. Clean Bedding Weekly: Flea eggs can live in your dog’s bedding.
  2. Vacuum Carpets & Furniture: Helps eliminate flea larvae.
  3. Use Year-Round: Pests are active even in cooler months.
  4. Pair with Environmental Sprays: For severe infestations.
  5. Keep Cats Away from Dogs Post-Treatment: Prevent accidental contact with Permethrin.

Shipping & Returns 

Shipping Policy:HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

K9 Advantix II for XL Dogs FAQs 

What is K9 Advantix II used for?

K9 Advantix II is used to kill and repel fleas, ticks, mosquitoes, biting flies, and lice in extra large dogs over 55 lbs, helping prevent infestations and vector-borne diseases.

How quickly does K9 Advantix II start working?

It begins killing fleas within 12 hours of application and ticks within 48 hours, offering full-spectrum monthly protection.

Can I bathe my dog after applying K9 Advantix II?

Yes, the product is waterproof. Wait at least 24 hours after application before bathing or swimming for best results.

Is it safe to use around cats or other small pets?

No, Permethrin is toxic to cats. Keep treated dogs away from cats for at least 24 hours post-application.

Can I use K9 Advantix II with other medications?

Always consult your vet before combining this treatment with other topical or oral medications.

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