Lisinopril 10mg and Hydrochlorothiazide 12.5mg Tablets

Lisinopril and Hydrochlorothiazide Tablets for Pet Hypertension

Product Description

Lisinopril 10 mg and Hydrochlorothiazide 12.5 mg Tablets pair a prescription-only ACE inhibitor with a thiazide diuretic in one tablet used off-label in dogs and cats for systemic hypertension. Lisinopril opens blood vessels by blocking angiotensin II, while hydrochlorothiazide clears excess sodium and water through the kidneys, tackling two key drivers of high blood pressure at once.

Benefits

• Dual Mechanism Action: An ACE inhibitor and a diuretic working together in one tablet tackle blood vessel tension and excess fluid volume at the same time.
• ACE Inhibitor Benefits: By shutting down angiotensin II, lisinopril lets blood vessels open up and takes pressure off the cardiovascular system in treated pets.
• Diuretic Fluid Reduction: Hydrochlorothiazide gets the kidneys moving excess sodium and water out of the body, helping pull fluid volume and blood pressure down.
• Hypertension Management: Addresses vasoconstriction and fluid retention together, hitting both key drivers of persistent high blood pressure in dogs and cats.
• Heart and Kidney Support: Lisinopril supports dogs with heart failure and addresses certain kidney disease types when paired with other cardiac medications.

Ingredients

Active Ingredients

How to Use

Dosage & Administration Instructions

Lisinopril 10 mg and Hydrochlorothiazide 12.5 mg Tablets are a prescription-only medication. A valid veterinarian prescription is required to purchase this product.

Please follow your veterinarian's instructions carefully for the dosage and administration of this medication.

Disclaimer: Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.

Placing a tablet inside a soft Pill Pocket or wrapping it in a small piece of your pet's favorite treat is a simple and caring way to make each dose easier for both of you. A pill pocket treat takes the stress out of medicating your pet and helps ensure no dose is missed. Shop Pill Pockets for Dogs | Shop Pill Pockets for Cats

Additional Information

Precautions

• ACE Inhibitor Allergy: Avoid in pets allergic to lisinopril, benazepril, enalapril, or any other medication within the ACE inhibitor class.
• Electrolyte Imbalance Risk: Persistent vomiting or diarrhea causing electrolyte disruption is a reason to avoid this product in affected pets.
• Severe Kidney Impairment: Both ingredients can add renal strain; use with extra care in pets already dealing with significant kidney disease.
• Pregnancy Caution: Both ingredients may harm developing fetuses or nursing young; never give to pregnant or lactating animals under any circumstances.
• Lupus and Autoimmune History: Tell your vet about any history of lupus, blood issues, or autoimmune conditions before this product is started.
• Potassium Level Risk: Hydrochlorothiazide depletes potassium; electrolyte levels must be monitored carefully when this product is used with other potassium-affecting drugs.
• Drug Interactions: Cholestyramine, colestipol, NSAIDs, potassium supplements, and ARBs such as losartan all interact with this combination in treated pets.
• Baseline Testing Required: Electrolytes, kidney values, and blood pressure all need a clean bill of health before treatment starts and should be revisited at regular intervals.
• Do Not Stop Abruptly: Speak to your vet before making any changes to this treatment; stopping suddenly can cause blood pressure to spike to a harmful level.
• Prescription Only: Neither ingredient has received veterinary FDA clearance; both require a licensed veterinarian to place the order before this product can go out.

Possible Side Effects

• Low Blood Pressure: Lethargy, weakness, and difficulty standing may signal low blood pressure developing in dogs or cats on this product.
• Kidney Dysfunction: Increased thirst or urination changes may signal kidney stress from lisinopril; monitor these signs closely throughout treatment.
• Electrolyte Abnormalities: Hydrochlorothiazide can cause low potassium, sodium, or magnesium, leading to muscle weakness or irregular heartbeat in treated pets.
• Vomiting and Diarrhea: Gastrointestinal reactions including vomiting and loose stools are among the more frequently reported side effects in treated pets.
• Reduced Appetite: Appetite loss can develop with lisinopril use; track food intake closely and flag any changes to your vet.
• Allergic Reactions: Hives, facial swelling, or breathing difficulty require immediate stopping of this product and urgent emergency veterinary attention.

Storage Information

• Room Temperature Storage: Store in a sealed container at room temperature, keeping the tablets away from moisture, heat, and direct light.
• Keep Container Sealed: A firmly closed lid between each use stops moisture and air from degrading these tablets over time.
• Keep Out of Reach: Store in a secure place that children and other household animals cannot get into to prevent accidental ingestion.

NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is the Lisinopril and Hydrochlorothiazide combination used for in pets?

Ans: Used off-label in dogs and cats for systemic hypertension, lisinopril opens blood vessels by blocking angiotensin II while hydrochlorothiazide reduces fluid volume through the kidneys. Together they address both vasoconstriction and fluid retention in one daily tablet.

Q2: Why is a combination tablet used instead of separate medications?

Ans: A single tablet covering two mechanisms makes sense when one medication alone is not getting blood pressure under control. It also cuts down on the number of individual pills an owner has to manage and administer each day.

Q3: What electrolyte changes should I watch for in my pet on this combination?

Ans: Hydrochlorothiazide can lower potassium, sodium, and magnesium levels, showing up as muscle weakness, lethargy, or an irregular heartbeat in affected pets. Regular blood tests throughout treatment are needed to keep electrolyte levels and kidney values within a safe range.

Q4: Can this medication affect my pet's kidneys?

Ans: Yes. Lisinopril has been linked to kidney dysfunction in some pets, and hydrochlorothiazide affects fluid and electrolyte balance. Heavier thirst or urination changes may signal kidney stress. Regular blood work and urinalysis throughout treatment help keep renal health in check.

Q5: Do I need a prescription for Lisinopril and Hydrochlorothiazide Tablets for my pet?

Ans: Yes, this is a prescription-only combination. Neither ingredient carries veterinary FDA approval, and both can only be dispensed on a licensed veterinarian's order. Regular monitoring appointments throughout treatment are an essential part of keeping your pet safe on this product.