Neo-Poly Gramicidin Ophthalmic Solution (10 ml)

Antibiotic Eye Drops for Bacterial Eye Infections in Dogs

Product Description

Neo-Poly Gramicidin Ophthalmic Solution is a prescription triple antibiotic sterile eye drop used by vets for superficial bacterial eye infections in dogs and cats. Neomycin blocks bacterial protein synthesis while polymyxin B and gramicidin disrupt cell wall permeability, together delivering broad-spectrum coverage. Each mL holds 1.75mg neomycin base, 10,000 units polymyxin B, and 0.025mg gramicidin for conjunctivitis, keratitis, blepharitis, and keratoconjunctivitis.

Benefits

• Triple Antibiotic Coverage: Combines three antibiotics with overlapping mechanisms to provide comprehensive broad-spectrum protection against susceptible ocular bacteria.
• Conjunctivitis Treatment: Effectively treats bacterial conjunctivitis, one of the most common external eye infections encountered in dogs and cats.
• Keratitis and Corneal Infections: Treats bacterial keratitis and keratoconjunctivitis affecting both the cornea and conjunctiva in dogs and cats.
• Eyelid Infection Treatment: Clears blepharitis and blepharoconjunctivitis, bacterial infections that affect the eyelids and surrounding eye tissue.
• FDA-Approved Generic: An FDA-approved generic ophthalmic solution made by multiple reputable manufacturers for reliable, consistent availability.

Ingredients

Active Ingredients

Neomycin Sulfate (equivalent to 1.75mg neomycin base per mL) Polymyxin B Sulfate (10,000 units per mL) Gramicidin (0.025mg per mL)

Inactive Ingredients

Sodium chloride, alcohol 0.5%, poloxamer 188, propylene glycol, purified water

How to Use

Neo-Poly Gramicidin Ophthalmic Solution is a prescription-only medication. A valid veterinarian prescription is required to purchase this product.

Please follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet.

Disclaimer: Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.

Additional Information

Precautions

• Ophthalmic Use Only: For the eye only; never put this solution in the ear or anywhere else on the body under any circumstances.
• Never Touch Dropper Tip: Keep the tip away from the eye, hands, and surfaces to protect the solution from contamination each time.
• Neomycin Allergy Caution: Cats may experience serious allergic reactions to neomycin; contact your veterinarian immediately if any adverse reactions are observed.
• Known Allergy Contraindication: Do not use in any pet with a confirmed allergy to neomycin, polymyxin B, gramicidin, or any ingredient in this solution.
• Not for Viral Infections: This solution only treats bacterial eye infections and will not work against viral, fungal, or parasitic conditions.
• Caution in Pregnancy: Use with caution in pregnant or nursing animals; always check with the vet before using in breeding animals.
• Complete the Full Course: Keep using the drops for the full treatment period even if the eye looks better to stop the infection coming back.

Possible Side Effects

• Local Eye Irritation: Mild stinging, redness, or discomfort upon application may occur and typically resolves quickly in most dogs and cats.
• Neomycin Hypersensitivity: Topical neomycin can cause local hypersensitivity reactions including redness, swelling, and discharge, particularly with prolonged use.
• Serious Allergic Reactions: Rare but serious systemic hypersensitivity reactions including anaphylaxis require immediate emergency veterinary attention if they occur.
• Antibiotic Resistance Risk: Using this solution longer or more often than needed can help resistant bacteria develop in the eye over time.

Storage Information

• Room Temperature Storage: Keep the bottle at room temperature away from sunlight, moisture, and heat sources at all times.
• Keep Cap Tightly Closed: Always replace the cap firmly after each application to maintain the sterility of the solution between uses.
• Keep Out of Reach: Put this medication somewhere children and untreated pets cannot get into it on their own.

Note: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What eye infections does Neo-Poly Gramicidin ophthalmic solution treat in dogs and cats?

Ans: Neo-Poly Gramicidin treats conjunctivitis, keratitis, keratoconjunctivitis, blepharitis, and blepharoconjunctivitis in dogs and cats. It covers a broad range of susceptible gram-positive and gram-negative bacteria. The vet confirms the infection is bacterial before prescribing this triple antibiotic solution.

Q2: How do the three antibiotics in this solution work together?

Ans: Neomycin shuts down bacterial protein production by targeting the ribosome. Polymyxin B punches holes in the bacterial cell membrane, causing the cell to fall apart. Gramicidin adds a second layer of membrane disruption. Together the three cover more bacterial types than any one antibiotic could manage alone.

Q3: Why must cats be monitored carefully when using this eye solution?

Ans: Neomycin can trigger serious allergic reactions in cats, showing up as worsening redness, swelling, discharge, or signs of broader distress. These reactions can escalate quickly so it is important to contact the vet right away rather than waiting if any of these signs develop after starting the drops.

Q4: Can Neo-Poly Gramicidin be used for viral or fungal eye infections in pets?

Ans: No, this solution only targets bacteria and will not help with viral, fungal, or parasitic eye infections at all. Using it for the wrong type of infection delays the right treatment and risks contributing to antibiotic resistance. The vet checks the eye first to confirm the cause before prescribing.

Q5: How many drops are in each 10mL bottle of Neo-Poly Gramicidin solution?

Ans: With about 20 drops per mL, a 10mL bottle comes out to roughly 200 drops in total. Dosed at one or two drops per eye every four to six hours, that amount tends to stretch across the full treatment course without running short. The vet nails down the exact schedule based on how bad the infection is and which eye structures are involved.

Clinical Research

• https://www.webmd.com/drugs/2/drug-2743/neomycin-polymyxin-gramicidin-ophthalmic-eye/details
• https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e6f8d2f6-adff-4ae1-982c-45562f0a8e28