Nobivac 1-DAPPv + L4 Vaccine for Dogs, 25 Doses

Combination Vaccine for Core Canine Diseases + Leptospirosis

Product Description

Nobivac 1-DAPPv + L4 Vaccine for Dogs, 25 Doses is a combination canine vaccine for healthy dogs 8 weeks of age and older. It helps protect against distemper, adenovirus type 1 (hepatitis), parainfluenza, parvovirus, and four Leptospira serovars (canicola, icterohaemorrhagiae, pomona, grippotyphosa). The vaccine is given as two 1 mL subcutaneous doses spaced 2-4 weeks apart.

NOTICE: This item requires Express shipping due to the perishable nature of this product. Express orders are shipped Monday-Wednesday. Cannot be shipped to a PO Box. Product can only be shipped to the continental US.

Benefits

• Broad Disease Coverage: Protects against core viral diseases and leptospirosis.
• Leptospira Protection: Contains four Leptospira serovars for expanded coverage.
• Leptospiruria Aid: Helps reduce Leptospira urinary shedding in exposed dogs.
• Clinic-Ready: Supplied in a 25-dose presentation.
• Ease of Administration: Given by subcutaneous injection following reconstitution.

Ingredients

Amphotericin B, gentamicin.

How to Use

Dosage & Administration Instructions

• Reconstitute Vaccine: Transfer the Lepto₄ vial into the Canine 1-DAPPv vial aseptically.
• Mix Gently: Mix until the solution is fully dissolved before use.
• Dose Size: Administer one 1 mL dose per vaccination.
• Primary Schedule: Give two doses subcutaneously, 2-4 weeks apart.
• Starting Age: Initial vaccination may begin at 8 weeks of age or older.

Additional Information

Precautions

• Cold Storage Required: Store at 2°-8°C and do not freeze.
• Healthy Dogs Only: Vaccinate only healthy, non-parasitized dogs.
• Not for Pregnant bitches: Do not vaccinate pregnant dogs.
• Hypersensitivity Risk: Biological products may cause severe reactions.
• Human Contact: If accidental human exposure occurs, seek medical advice.

Shipping & Returns

We offer express delivery for this product; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Frequently Asked Questions

Q1: What does Nobivac 1-DAPPv + L4 Vaccine for Dogs protect against?

Ans: Nobivac 1-DAPPv + L4 Vaccine for Dogs is shown to be effective for healthy dogs 8 weeks and older against distemper, adenovirus type 1 (hepatitis), parainfluenza, parvovirus, and four Leptospira serovars: canicola, icterohaemorrhagiae, pomona, and grippotyphosa.

Q2: At what age can puppies receive this vaccine?

Ans: Puppies may begin the Nobivac 1-DAPPv + L4 vaccination series at 8 weeks of age or older, with the second dose given 2–4 weeks after the first to complete the primary series.

Q3: What is the vaccination schedule for this product?

Ans:  The primary vaccination series consists of two 1 mL doses given subcutaneously, with the second dose administered 2–4 weeks after the first dose.

Q4: How is the vaccine prepared before injection?

Ans: The Lepto₄ vial is aseptically transferred into the Canine 1-DAPPv vial and mixed gently until completely dissolved before subcutaneous injection.

Q5: Does this vaccine help reduce leptospirosis shedding?

Ans: Yes, Nobivac 1-DAPPv + L4 is effective against leptospiruria (urinary shedding of Leptospira) caused by the four included serovars, which supports infection control in at-risk environments.

Q6: What preservatives are included in this vaccine?

Ans: The vaccine contains gentamicin and amphotericin B as preservatives, as listed on the veterinary label information.

Q7: How often are boosters needed after the initial series?

Ans: The duration of immunity has not been established; revaccination frequency should be discussed with a veterinarian or according to manufacturer guidance.

Q8: What are essential storage and handling precautions?

Ans: Store the vaccine refrigerated at 2°–8 °C, do not freeze, use sterile syringes, and follow proper handling to maintain vaccine integrity.

Q9: Are there dogs that should not receive this vaccine?

Ans: Vaccinate only healthy, non-parasitized dogs and avoid use in pregnant bitches; biologicals may cause hypersensitivity reactions requiring veterinary monitoring.

Q10: Why does this product require express shipping?

Ans: Nobivac 1-DAPPv + L4 is a temperature-sensitive biological vaccine that requires Express shipping to maintain proper refrigeration during transit and ensure product integrity on delivery.