Nuflor Injection – Broad-Spectrum Antibiotic for Cattle

Nuflor (Florfenicol) Injectable Solution is commonly administered for the treatment and management of bovine respiratory disease in cattle. The onset of action is rapid and long-lasting, thus affording effective protection against the bacterial pathogens Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni. The product has wide use in veterinary medicine and provides flexibility in single- and multiple-dose administration.

Benefits:

• Broad-Spectrum Antibiotic – Cures BRD fast and other bacterial diseases of cattle.
• Quick-acting and long-acting - cures quick and long-lasting defense.
• Several Dosing Alternative – Either a single dose or multiple doses as treatment.
• No Milk Withdrawal for Non-Milking Cattle – Beef and non-milking dairy cattle may be treated with this indication.
• Veterinarian-Preferred & Proven Effective – Reliable antibiotic for managing respiratory disease in cattle.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

What is the dose for Nuflor?

The administration of Nuflor can either be done via the intramuscular route or by subcutaneous injection following how often the therapy is given. Always ensure to follow the veterinarian's instructions as to the dosing and method of administration.

What is Nuflor used for?

Nuflor in particular is administered to manage bovine respiratory disease caused by Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni in minimizing sickness and impaired herd health.

Dosage & Administration:

For treatment of bovine respiratory disease (BRD) and bovine interdigital phlegmon (foot rot): NUFLOR Injectable Solution should be administered by intramuscular injection to cattle at a dose rate of 20 mg/kg body weight (3 mL/100 lbs). A second dose should be administered 48 hours later. Alternatively, NUFLOR Injectable Solution can be administered by a single subcutaneous (SC) injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs). Do not administer more than 10 mL at each site. The injection should be given only in the neck.

NOTE: Intramuscular injection may result in local tissue reaction that persists beyond 28 days. This may result in trim loss of edible tissue at slaughter. Tissue reaction at injection sites other than the neck is likely to be more severe.

For control of respiratory disease in cattle at high risk of developing BRD: NUFLOR Injectable Solution should be administered by a single subcutaneous injection to cattle at a dose rate of 40 mg/kg body weight (6 mL/100 lbs). Do not administer more than 10 mL at each site. The injection should be given only in the neck.

NUFLOR INJECTABLE SOLUTION DOSAGE GUIDE

Do not inject more than 10 mL per injection site.

Clinical improvement should be evident in most treated subjects within 24 hours of initiation of treatment. If a positive response is not noted within 72 hours of initiation of treatment, the diagnosis should be re-evaluated.

Contraindications:

Do not use in animals that have shown hypersensitivity to florfenicol.

Warnings:

Not For Human Use. Keep Out of Reach of Children. This product contains materials that can be irritating to the skin and eyes. Avoid direct contact with skin, eyes, and clothing. In case of accidental eye exposure, flush with water for 15 minutes. In case of accidental skin exposure, wash with soap and water. Remove contaminated clothing. Consult a physician if irritation persists. Accidental injection of this product may cause local irritation. Consult a physician immediately. The Safety Data Sheet (SDS) contains more detailed occupational safety information.

To report suspected adverse drug events, for technical assistance or to obtain a copy of the Safety Data Sheet (SDS), contact Norbrook at 1-866-591-5777.

Precautions:

Not for use in animals intended for breeding purposes. The effects of florfenicol on bovine reproductive performance, pregnancy, and lactation have not been determined. Toxicity studies in dogs, rats, and mice have associated the use of florfenicol with testicular degeneration and atrophy. Intramuscular injection may result in local tissue reaction which persists beyond 28 days. This may result in trim loss of edible tissue at slaughter. Tissue reaction at injection sites other than the neck is likely to be more severe.

Residue Warnings:

Animals intended for human consumption must not be slaughtered within 28 days of the last intramuscular treatment. Animals intended for human consumption must not be slaughtered within 33 days of subcutaneous treatment. This product is not approved for use in female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may cause drug residues in milk and/or in calves born to these cows. A withdrawal period has not been established in pre-ruminating calves. Do not use in calves to be processed for veal.

Storage:

Store at or below 77°F (25°C). Refrigeration is not required. Excursions permitted up to 86°F (30°C). Brief exposure to temperatures up to 104°F (40°C) may be tolerated provided the mean kinetic temperature does not exceed 77°F (25°C); however, such exposure should be minimized. The solution is light yellow to straw-colored. Color does not affect potency.

Use within 28 days of the first vial puncture.

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FAQ

What is Nuflor employed for?

Nuflor generally is an antibiotic used to treat Bovine Respiratory Disease (BRD) and other bacterial infections in beef cattle and non-lactating dairy cattle.

What is the way to administer Nuflor?

Nuflor can be administered either IM or SQ. The procedure must always follow the specified directions for dosage and administration found on the product label or given by the veterinarian.

What is the slaughter withdrawal time after using Nuflor?

IM injection: Cattle must not be slaughtered for meat within 28 days of the last treatment.

SQ injection: Cattle must not be slaughtered for meat within 38 days of the last treatment.

May Nuflor be given to lactating dairy cows?

No, Nuflor is not labeled for use in lactating dairy cattle for milk that will be consumed by humans.

Are there any side effects of Nuflor?

Swelling at the injection site and, on occasion, loss of appetite or diarrhea may be seen in some cattle. If severe reactions are observed, consult a veterinarian.

May Nuflor be used in other animals?

Nuflor is intended for use in cattle and should not be used in other animals unless directed by a veterinarian.