Normosol-R Electrolyte Injection Solution (1000 ml)

Balanced Electrolyte Fluid Solution for Rehydration and Fluid Replacement in Pets

Product Description

Normosol-R is a sterile, isotonic balanced electrolyte solution given intravenously or subcutaneously to replace extracellular fluid losses in animals. It treats dehydration, supports kidney disease management, restores fluid volume lost during surgery, trauma, burns, or shock, and maintains circulation during moderate blood loss. Its electrolyte profile closely matches normal plasma, delivering physiologically balanced sodium, potassium, magnesium, chloride, acetate, and gluconate with no antimicrobial agents or added buffers.

Benefits

• Electrolyte Balance: Its balanced electrolyte profile maintains physiologic sodium-to-chloride ratios with normal potassium and magnesium levels.
• Fluid Volume Replacement: Indicated for replacing extracellular fluid lost due to surgery, trauma, burns, or shock.
• Kidney Function Support: Helps maintain hydration and kidney function in pets with chronic kidney disease.
• Blood Loss Recovery: Used as an adjunct to recover circulatory volume after moderate surgical or post-surgical blood loss.
• Mild Antiacidotic Action: Acetate and gluconate ions serve as bicarbonate sources, offering mild antiacidotic action during replacement therapy.
• Additive-Free Formula: Free from bacteriostatic agents, antimicrobial additives, and supplementary buffers, reducing unwanted additive exposure for patients.
• IV and SQ Compatible: Can be given intravenously or subcutaneously, offering veterinarians and trained pet owners practical delivery flexibility.

Ingredients

Composition Table (per 100 mL)

Guaranteed Analysis

Other Ingredients:

Water for Injection, USP. May contain HCl and/or NaOH for pH adjustment. pH 6.6 (4.0 to 8.0); osmolarity approximately 294 mOsmol/liter.

How to Use

Directions for Use

• Prescription and Veterinary Guidance Required: Normosol-R is a prescription product; always administer under veterinary supervision or following specific instructions provided by your veterinarian.
• Inspect Solution Before Use: Do not administer unless the solution is clear, colorless, and the bag is completely undamaged and intact; discard any bag that appears compromised or contains particles.
• Administer IV or Subcutaneously: Normosol-R may be given intravenously or subcutaneously; the preferred route and infusion rate will be determined by your veterinarian based on the individual patient's fluid deficit.
• Dose Based on Individual Fluid Loss: The amount to be infused is based on replacing the estimated losses of extracellular fluid volume specific to each individual patient's needs and condition.
• Surgical Use Guideline: Up to 3 times the estimated blood loss volume during and after surgery may be given to correct circulatory volume when there is only moderate blood loss.
• Single-Dose Use Only: This solution is intended for single-dose use only; discard any unused portion after each administration to prevent contamination.
• Do Not Add Incompatible Medications: If additives are needed, use aseptic technique and mix thoroughly; consult a pharmacist regarding compatibility before adding any other drugs to the solution.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any fluid therapy for your pet.

Additional Information

Precautions

• Heart and Kidney Caution: Pets with congestive heart failure, renal insufficiency, or conditions that cause sodium or potassium buildup need very careful management when using this solution.
• Not a Blood Substitute: When a pet is experiencing uncontrolled bleeding or a serious drop in red cell volume, whole blood or packed red cells are still needed and cannot be replaced by this solution.
• Acidosis and Electrolyte Limits: This solution is not the right choice for correcting severe acidosis, significant electrolyte deficits, or situations where a plasma or blood expander is specifically needed.
• Alkalosis Risk Advisory: Pets dealing with metabolic or respiratory alkalosis, or those with severe liver insufficiency that affects how their body processes ions, should receive this solution with extra care.
• Fluid Overload Monitoring: Giving fluids through an IV can lead to diluted electrolytes, overhydration, or fluid buildup in the lungs, so keeping a close eye on your pet during the infusion is really important.
• Elderly Pet Caution: Older pets tend to have weaker kidney function, which makes them more vulnerable to fluid overloading and low sodium levels; dosing should be done carefully with regular kidney monitoring.
• Safe Needle Disposal: All used needles and syringes should go straight into a sharps container; head to SafeNeedleDisposal.org to find the right disposal option in your area.

Possible Side Effects

• Injection Site Reactions: Poor sterile technique during administration can lead to infection, abscess, or pain at the injection site; always use a clean, sterile needle.
• Fever After Infusion: Some pets may develop a fever-like reaction after receiving the fluid; stop the infusion right away and call your vet if this happens.
• Vein Irritation: Swelling, redness, or hardness along the vein at the IV site has been reported after intravenous use; contact your vet if you notice any of these signs.
• Fluid Buildup: A small amount of fluid may collect under the skin at the injection site after subcutaneous delivery; this usually goes away on its own before the next dose.
• Allergic Reactions: Stop the infusion right away and get emergency vet care if your pet shows facial swelling, hives, vomiting, seizures, pale gums, or cold limbs.
• Overhydration: Giving too much fluid can cause overhydration, low sodium levels, or fluid in the lungs; stop the infusion and contact your vet for guidance if this occurs.

Storage Information

• Store at Room Temperature: Keep the solution stored at room temperature away from direct light; do not expose to temperatures above 25°C/77°F for extended periods as this may cause minor moisture loss from the bag.
• Do Not Freeze: Do not freeze the solution, as freezing can alter the concentration and composition of the electrolytes, making it unsafe for use.
• Discard Unused Portion: Since this is a single-dose solution with no antimicrobial preservatives, any remaining fluid after a dose must be discarded and never stored for reuse.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy. 

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What conditions is Normosol-R used to treat in dogs and cats?

Ans: Normosol-R is given to pets that have lost a significant amount of fluid due to surgery, trauma, burns, or shock. Vets also prescribe it to address dehydration from low fluid intake, support treatment in pets with kidney disease, and help bring circulatory volume back to a safe level after moderate blood loss.

Q2: How is Normosol-R different from regular saline for fluid therapy in pets?

Ans: Unlike plain saline only contains sodium chloride. Normosol-R, on the other hand, is a balanced multi-electrolyte solution that reflects the natural composition of plasma. It delivers sodium, potassium, magnesium, chloride, acetate, and gluconate. The acetate and gluconate also give it a mild antiacidotic benefit, something plain saline simply does not offer.

Q3: Can Normosol-R be given at home to my cat or dog?

Ans: Yes, Normosol-R can be given at home under the skin, as long as your vet has approved it. This is actually quite common for cats and dogs with chronic kidney disease. Your vet will show you the right technique, how much to give, and how often before you do it on your own.

Q4: Can Normosol-R replace a blood transfusion in my pet?

Ans: No, Normosol-R is not a replacement for whole blood or packed red cells when bleeding is severe or out of control. It can help keep circulatory volume stable with moderate blood loss, but once red cell volume drops critically low, there is no getting around the need for blood products.

Q5: Can I save unused Normosol-R solution after opening the bag for my pet's next dose?

Ans: No, Normosol-R has no preservatives, so it is a single-use solution only. Whatever is left after each dose needs to be thrown away right away. Holding onto unused fluid is not safe, as it can become contaminated and harm your pet during the next treatment.