Proin ER Chewable Tablets for Dogs, 145 mg

Controls Urinary Incontinence in Dogs Effectively

Product Description

PROIN ER Chewable Tablets for Dogs are veterinarian-prescribed extended-release tablets formulated to help control urinary incontinence caused by urethral sphincter hypotonus. The medication contains phenylpropanolamine hydrochloride, an alpha-adrenergic agent that increases urethral muscle tone to improve bladder control. Designed for convenient once-daily dosing, these tablets support long-term management of urinary leakage in dogs when administered with food.

Please note product may arrive in a Hardy Paw Pharmacy vial, manufacturer packaging is shown for reference. 

*Signature Is Required Upon Delivery In The Following States: Arkansas, Illinois, Iowa, Louisiana, Oregon, West Virginia

Benefits

• Supports Bladder Control: Helps control urinary incontinence in dogs caused by urethral sphincter hypotonus by increasing urethral muscle tone.
• Once Daily Dosing: Extended release formulation allows convenient once daily administration for effective long-term management of urinary leakage.
• Improves Urethral Tone: Phenylpropanolamine stimulates adrenergic receptors to enhance smooth muscle tone in the urethra and bladder neck.
• Veterinarian Prescribed Treatment: FDA-approved veterinary medication indicated specifically for managing urinary incontinence associated with urethral sphincter hypotonus.
• Extended Release Formula: Controlled-release tablets help maintain therapeutic levels of phenylpropanolamine for sustained urinary control.

Variants

PROIN ER Chewable Tablets are available in the following strengths:

• PROIN ER Chewable Tablets 18 mg tablets
• PROIN ER Chewable Tablets 38 mg tablets
• PROIN ER Chewable Tablets 74 mg tablets
• PROIN ER Chewable Tablets 145 mg tablets

Ingredients

Composition Table

How to Use

Recommended-Dosage Chart

Dosage & Administration Instructions

• Once Daily Dose: Administer PROIN ER at a recommended dosage of 2 to 4 mg/kg body weight once daily.
• Give With Food: Administer tablets with food to support consistent absorption and improve dosing tolerance in dogs.
• Do Not Crush: Tablets must not be split or crushed because the extended release formulation ensures proper drug delivery.
• Prescription Required: This medication is restricted to use by or on the order of a licensed veterinarian.
• Small Dogs Warning: Dogs weighing under 10 pounds should not receive this product due to dosing safety limitations.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Underlying Conditions: Use cautiously in dogs with heart disease, hypertension, liver disease, kidney insufficiency, diabetes, or glaucoma.
• Drug Interactions: Use carefully with sympathomimetic drugs, tricyclic antidepressants, monoamine oxidase inhibitors, or halogenated anesthetics.
• Incontinence Causes: The medication may mask incontinence caused by urinary tract infections and is ineffective for neurologic causes.
• Breeding Safety: The safety of this medication has not been studied in breeding dogs or in dogs that are pregnant or nursing.
• Water Availability: Dogs may feel more thirsty while taking this medication, so they should always have access to clean, fresh water.

Possible Side Effects

• Digestive Problems: While using phenylpropanolamine tablets, some pets may experience vomiting, loose stools, reduced appetite, or excessive drooling.
• Changes in Blood Pressure: The medication may cause higher blood pressure and a faster heartbeat during treatment, so regular checks by a veterinarian are important.
• Behavioral Changes: Anxiety, agitation, vocalization, confusion, and restlessness have been reported in some treated dogs.
• Neurologic Effects: Tremors, seizures, ataxia, or nervous system disturbances may occur rarely in some dogs.
• Urinary Effects: Proteinuria, urinary tract infections, urinary retention, or hematuria have been reported during treatment.

Storage Information

• Room Temperature Storage: Store the tablets within the recommended 20°C–25°C room temperature range to help preserve product quality.
• Temperature Excursions: Short temperature variations between 15°C and 40°C are permitted during storage and handling.
• Secure Storage: Keep the medication in a secure location away from pets and other animals to prevent accidental ingestion.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is PROIN ER used for in dogs?

Ans: PROIN ER Chewable Tablets are used to control urinary incontinence in dogs caused by urethral sphincter hypotonus. The medication contains phenylpropanolamine hydrochloride, which helps increase urethral muscle tone and improves bladder control, reducing urine leakage when administered as directed by a veterinarian.

Q2: How often should PROIN ER be given to dogs?

Ans: PROIN ER is formulated as an extended-release medication and is generally given once a day based on the dog’s body weight and the veterinarian’s recommended dosage. The tablet should be administered with food and should not be crushed, broken, or divided, as this may interfere with the intended slow release of the medication.

Q3: Can small dogs take PROIN ER tablets?

Ans: Dogs weighing less than 10 pounds should not receive PROIN ER because tablet dosing may exceed the safe recommended dosage of phenylpropanolamine. Veterinarians determine appropriate treatment options and dosing adjustments based on a dog’s body weight and health condition.

Q4: Are there any side effects associated with PROIN ER for dogs?

Ans: Some dogs may develop side effects such as vomiting, diarrhea, reduced appetite, weight loss, high blood pressure, or changes in behavior while taking PROIN ER. If a dog shows any unusual signs or noticeable changes in health during treatment, the pet owner should reach out to a veterinarian as soon as possible for proper advice and evaluation.

Q5: How should PROIN ER tablets be stored?

Ans: Keep PROIN ER tablets in normal indoor conditions, ideally within the 20°C–25°C temperature range. Short periods of exposure to temperatures as low as 15°C or as high as 40°C will not affect the product. The medicine should be placed in a protected storage area where children and animals cannot reach it to avoid accidental consumption.