Proin ER Chewable Tablets for Dogs, 38mg

Effective Urinary Incontinence Control Tablets for Dogs

Product Description

PROIN ER 38 mg is a vet-prescribed extended-release tablet. It is designed to help control urinary incontinence in dogs caused by weak urethral sphincters. The tablet contains phenylpropanolamine hydrochloride. This substance increases urethral muscle tone and improves bladder control. With its convenient once-daily dosing and controlled drug release, PROIN helps reduce urine leakage. It supports better urinary management in dogs under veterinary care.

Signature Is Required Upon Delivery In The Following States: Arkansas, Illinois, Iowa, Louisiana, Oregon, and West Virginia

Benefits

• Urinary Control Support: Helps manage urinary incontinence in dogs by strengthening urethral sphincter tone and reducing involuntary urine leakage.
• Once-Daily Dosing: The extended-release formulation allows for easy once-a-day administration, making long-term treatment simpler.
• Targeted Mechanism: Phenylpropanolamine stimulates adrenergic receptors, which increase urethral closure pressure and improve bladder control in dogs.
• Veterinary-Approved Treatment: FDA-approved prescription medication specifically indicated for urinary incontinence caused by urethral sphincter weakness in dogs.
• Weight-Based Strengths: Available in multiple dosage strengths to support accurate dosing for dogs across different body weight ranges.

Variants

18 mg tablets
38 mg tablets
74 mg tablets
145 mg tablets

Ingredients

Phenylpropanolamine Hydrochloride 38 mg

How to Use

Recommended-Dosage Chart

Dosage & Administration Instructions

• Give With Food: Administer PROIN ER tablets with food to help support proper absorption and consistent drug activity.
• Do Not Split: Extended-release tablets must not be split, crushed, or altered because this may affect controlled drug release.
• Weight-Based Dosing: Dose dogs according to body weight using the labeled tablet strengths to maintain recommended therapeutic dosing.
• Veterinary Prescription: This medication is restricted for veterinary use and should only be administered under the direction of a licensed veterinarian.
• Monitor Consumption: Ensure the dog consumes the entire tablet after dosing and contact a veterinarian if dosing difficulties occur.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Underlying Conditions: Use cautiously in dogs with heart disease, hypertension, kidney disease, diabetes, glaucoma, or liver disorders.
• Drug Interactions: Use cautiously with sympathomimetic drugs, tricyclic antidepressants, monoamine oxidase inhibitors, or certain anesthetics.
• Diagnostic Awareness: This medication may mask urinary incontinence symptoms caused by urinary tract infections or other underlying conditions.
• Breeding Safety: Safety has not been established for dogs intended for breeding or those that are pregnant or lactating.

Possible Side Effects

• Digestive upset: Some dogs may vomit, have diarrhea, or show a reduced appetite during treatment.
• Blood pressure changes: Some dogs may have increased blood pressure or heart rate changes, such as tachycardia.
• Behavior changes: Dogs might experience restlessness, agitation, or lethargy while receiving phenylpropanolamine treatment.
• Weight changes: A significant body weight reduction during long treatment periods has been noticed in dogs.

Storage Information

• Room Temperature: Store tablets at controlled room temperature ranging between 20°C and 25°C for optimal stability.
• Temperature Excursions: Short temperature variations between 15°C and 40°C are permitted during storage and transportation.
• Secure Storage: Keep medication stored securely away from the reach of pets and children to prevent accidental exposure and ingestion.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy. 

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is PROIN ER 38 mg used for in dogs?

Ans: PROIN ER 38 mg is a prescription medication used to control urinary incontinence in dogs caused by urethral sphincter hypotonus. It works by increasing urethral muscle tone, helping reduce urine leakage, improve bladder control, and, in affected dogs,s when administered under veterinary supervision.

Q2: How does PROIN ER help manage urinary incontinence in dogs?

Ans: PROIN ER contains phenylpropanolamine hydrochloride, an alpha-adrenergic agent that increases urethral sphincter tone. By stimulating adrenergic receptors and promoting norepinephrine release, it improves urethral closure pressure, helping dogs maintain better urinary control and reducing accidental urine leakage.

Q3: How should PROIN ER tablets be given to dogs?

Ans: PROIN ER tablets should be given once a day with food, based on the dosage recommended by a veterinarian. The tablets must not be split or crushed, as they are extended-release. Owners should make sure the dog takes the full dose during administration.

Q4: Are there any common side effects of PROIN ER in dogs?

Ans: Some dogs may experience side effects such as vomiting, diarrhea, decreased appetite, weight loss, lethargy, or increased blood pressure during treatment. These reactions were reported during clinical studies and should be discussed with a veterinarian if they occur or worsen.

Q5: Can all dogs take PROIN ER for urinary incontinence?

Ans: PROIN ER is not suitable for every dog and should only be used with veterinary guidance. It may not work for incontinence caused by neurologic disease or anatomical issues. Use it carefully in dogs with heart disease, high blood pressure, or specific medical conditions.