Protazil (1.56% diclazuril) Antiprotozoal Pellets for Horses (2.4 lb)

EPM Treatment Pellets for Horses

Product Description

PROTAZIL® Antiprotozoal Pellets provide an easy daily top-dress treatment for equine protozoal myeloencephalitis (EPM) in horses caused by Sarcocystis neurona. Each alfalfa-based pellet contains 1.56% diclazuril for consistent dosing. Designed to be mixed with feed and given once a day for 28 days, it supports a precise and practical approach to managing this serious neurological disease.

Benefits

• Trusted EPM Treatment: A clinically approved therapy developed specifically to treat equine protozoal myeloencephalitis (EPM) in horses, giving you confidence in your horse’s care.
• Simple, Stress-Free Dosing: These easy-to-use pellets mix right into your horse’s daily grain, so treatment fits seamlessly into your regular feeding routine—no extra hassle, just consistent daily dosing.
• Precise, Weight-Based Formula: The 1.56% diclazuril formulation is carefully measured to deliver accurate dosing based on your horse’s weight.
• Veterinarian Recommended: This prescription medication is trusted and used by equine health professionals to support effective treatment.
• Convenient Packaging: One 2.4-lb bucket treats an average 1,274-lb horse for the full 28-day course.

Ingredients

Active Ingredient

PROTAZIL® contains diclazuril at 1.56 percent as the active antiparasitic compound.

Inactive Ingredients

Inactive components include dehydrated alfalfa meal, wheat middlings, cane molasses, and propionic acid as a preservative

How to Use

Recommended-Dosage Chart

Dosage: 1 mg diclazuril per kg body weight, administered once daily for 28 days.

Dosage & Administration Instructions

• Weigh First: Start by weighing your horse—or use a weight tape—to make sure you’re calculating the correct dose.
• Mix with Feed: Simply top-dress the pellets onto your horse’s regular grain ration and mix them in well.
• Give Daily for 28 Days: Administer the calculated dose once a day for 28 straight days to complete the full course.
• Use the Scoop Guide: Refer to the dosing chart and the markings on the included scoop to match your horse’s weight range accurately.
• Prescription Only: This medication is available by prescription and can only be used under the direction of a licensed veterinarian, as required by federal law.

Additional Information

Precautions

• Breeding Safety Unknown: Safe use in breeding horses has not been evaluated.
• Pregnancy Caution: Safety during pregnancy or lactation has not been determined.
• Concurrent Therapies: Safety with other medications or therapies has not been evaluated.
• Human Consumption Ban: Do not use in horses intended for human consumption.

Possible Side Effects

• No Field Reactions: No adverse effects were attributed to diclazuril in field studies.
• Reported Events: In rare cases, neurological signs, recumbency, stiffness, or laminitis-like symptoms have been reported, with isolated incidents of unexplained death.
• High Dose Effects: Elevated BUN, creatinine, and reduced weight gain observed at high doses.

Storage Information

• Temperature Range: Store between 15°C and 30°C or 59°F to 86°F.
• Secure Location: Keep out of reach of children.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy. 

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.  

Frequently Asked Questions

Q1: What is PROTAZIL® used for in horses?

Ans: PROTAZIL® is used to treat equine protozoal myeloencephalitis (EPM), a serious neurological condition caused by Sarcocystis neurona. It’s an FDA-approved antiprotozoal medication developed specifically for horses. Because it’s a prescription treatment, it should always be administered under the direction of a licensed veterinarian.

Q2: How is PROTAZIL® administered to horses?

Ans: PROTAZIL® is administered as a top dress mixed into the horse’s daily grain ration. The recommended dose is 1 mg diclazuril per kg of body weight given once daily for 28 consecutive days, using the provided dosing chart for accuracy.

Q3: Is PROTAZIL® a prescription medication?

Ans: Yes, PROTAZIL® is available only with a prescription. Federal regulations limit its use to administration by a licensed veterinarian or under their direct authorization. It is not available for over-the-counter purchase and must be administered under veterinary guidance.

Q4: Are there any known side effects of PROTAZIL®?

Ans: In field studies, no adverse effects were attributed directly to diclazuril at the labeled dose. Two adverse events were reported during safety evaluation, though causation was not definitively established. Always monitor horses closely and consult your veterinarian with concerns.

Q5: How should PROTAZIL® be stored?

Ans: PROTAZIL® should be stored in a room temperature setting, within 15°C to 30°C, equivalent to 59°F through 86°F. Keep the product in a secure location and out of reach of children to ensure safe handling.