Semglee (insulin glargine-yfgn) U-100 Injectable, 10 mL Multi-Dose Vial

NOTICE: This item requires Express shipping due to the perishable nature of this product. Express orders are shipped Monday-Wednesday.

Semglee U-100 Injectable

Semglee (insulin glargine-yfgn) U-100 is a long-acting insulin designed to manage diabetes mellitus in dogs and cats. This FDA-approved medication is interchangeable with Lantus, ensuring reliable glycemic control. Its formulation delivers a steady release, making it effective for both initial treatment and long-term management of diabetes. Semglee is particularly recommended as the first-choice insulin for newly diagnosed diabetic cats and is also suitable for dogs when other insulins don’t provide adequate duration of activity.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE

What Are the Benefits of Semglee Insulin U-100 for Pets?

• Steady and Predictable Action: Ensures long-lasting glycemic control, reducing the risk of blood sugar spikes and drops.
• FDA-Approved Interchangeability: Recognized as a safe alternative to Lantus, offering comparable efficacy and quality.
• Versatile for Dogs and Cats: Ideal for cats as a primary insulin choice; can also benefit dogs requiring extended duration coverage.
• Clinically Formulated for Safety: Contains precise inactive ingredients to support stability and effectiveness.
• Veterinarian-Recommended: Backed by clinical studies for its efficacy in managing uncomplicated diabetes mellitus.

How to Use Semglee Insulin U-100?

Administration Guidelines:

• Use only with U-100 syringes.
• Administer injections subcutaneously (under the skin) as directed by your veterinarian.
• Always double-check the dose in the syringe before administering to your pet.

Dosage and Administration:

• Always consult your veterinarian for specific dosage instructions tailored to your pet's condition. The required dose may vary based on blood glucose monitoring and clinical response.

What Are the Ingredients in Semglee Insulin U-100?

Each milliliter contains:

• Active Ingredient: 100 units (3.64 mg) of insulin glargine.
• Inactive Ingredients:
  • 30 mcg zinc.
  • 20 mg glycerol 85%.
  • 2.7 mg m-Cresol.
  • Water for injection.

Are There Any Side Effects or Warnings?

Possible Side Effects:

• Hypoglycemia (low blood sugar) characterized by lethargy, tremors, or seizures.
• Rare local site reactions like redness or swelling.

Warnings:

• Administer under veterinary supervision.
• Monitor blood glucose levels as instructed by your vet.
• Not for use in animals with known hypersensitivity to insulin glargine or its ingredients.

How Should Semglee Insulin Be Stored?

Proper storage ensures the effectiveness and safety of the product:

• Unopened Vials:
  • Refrigerate at 2°C to 8°C (36°F-46°F) in the original carton.
  • Do not freeze; discard if frozen.
• Opened/In-Use Vials:
  • Can be stored at room temperature (below 30°C or 86°F) or refrigerated.
  • Must be discarded 28 days after first use.
  • Avoid direct sunlight or excessive heat.

Discard Criteria:

• Dispose of if the solution appears discolored, cloudy, or contains visible particles.

Shipping & Returns 

Shipping Policy: We offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

FAQs - Semglee Insulin U-100 for Diabetes Mellitus in Dogs and Cats

What is Semglee Insulin U-100 used for?

Semglee Insulin U-100 is used to manage diabetes mellitus in dogs and cats by providing long-acting blood glucose control. It helps stabilize blood sugar levels and prevent complications related to diabetes, such as hypoglycemia or hyperglycemia.

Can Semglee Insulin U-100 be used for both cats and dogs?

Yes, Semglee Insulin U-100 is effective for both cats and dogs. It is a first-choice treatment for newly diagnosed diabetic cats and is an option for dogs when other insulins don’t offer adequate duration.

How do I know if my pet is responding to Semglee Insulin?

Monitor your pet’s behavior, appetite, and energy levels while tracking blood glucose readings. Signs of good response include stable blood sugar levels, reduced thirst, and a normal appetite. Consult your veterinarian for regular evaluations.

How should I handle missed doses of Semglee Insulin?

If a dose is missed, contact your veterinarian immediately for guidance. Do not double the dose or adjust the schedule without professional advice to avoid adverse effects.

Can Semglee Insulin U-100 cause side effects in pets?

Yes, potential side effects include hypoglycemia (low blood sugar), which may present as lethargy, tremors, or seizures. Injection site reactions are rare but possible. Report any unusual symptoms to your veterinarian promptly.

Is there a specific diet recommended for pets on Semglee Insulin?

Pets on insulin therapy often benefit from a consistent diet low in simple carbohydrates and high in protein. Your veterinarian can recommend an appropriate feeding schedule and diet tailored to your pet’s needs.

How is Semglee Insulin U-100 different from short-acting insulins?

Semglee Insulin U-100 is a long-acting insulin designed to maintain stable blood sugar levels over 24 hours. Short-acting insulins work more rapidly but require multiple daily doses and may not provide steady glucose control.

Can I store Semglee Insulin in a regular household refrigerator?

Yes, unopened vials should be stored in a refrigerator between 2°C and 8°C. Avoid freezing the product, and ensure the vials are kept away from direct sunlight or heat for optimal efficacy.

What should I do if my pet shows signs of hypoglycemia after insulin administration?

Immediately provide a small amount of glucose or sugar (e.g., corn syrup or honey) and contact your veterinarian. Do not administer additional insulin until your veterinarian has been consulted.

Is Semglee Insulin U-100 covered by pet insurance?

Coverage for Semglee Insulin U-100 depends on your pet insurance provider and policy. It is recommended to review your policy or contact your insurer for specific details regarding insulin coverage.

Clinical Research:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/761201Orig1s000lbl.pdf

https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=3ac85ebb-5594-59c8-77fd-df254329d151&type=display