Semintra (telmisartan) Oral Solution for Cats (35 ml) - Manage Hypertension

The Only FDA-Approved Liquid Treatment for Systemic Hypertension in Cats

Product Description

Semintra (Telmisartan) Oral Solution 10 mg/mL is the first and only FDA-approved prescription treatment for systemic hypertension in cats, supplied in a 45 mL plastic bottle with 35 mL fill and a calibrated dosing syringe (NDC 0010-4492-01). Each mL contains 10 mg telmisartan — a non-peptide, selective angiotensin II subtype 1 (AT1) receptor blocker that lowers blood pressure by blocking the RAAS pathway. The clear, colorless to yellowish viscous solution can be given by syringe directly into the cat's mouth or placed on a small amount of food, making pill-free daily blood pressure management straightforward for cat owners.

Benefits

• Only FDA-Approved Feline Hypertension Treatment: Semintra is the sole FDA-approved medication specifically indicated for controlling systemic hypertension in cats.
• Lowers Blood Pressure Within 14 Days: Clinical studies show Semintra safely brings feline blood pressure down to a healthy range within the two-week initiating phase.
• Pill-Free Liquid Dosing: The oral solution completely removes the need for daily pilling, which can be stressful for cats and damaging to the owner-cat relationship over time.
• Precision Dosing Syringe Included: Every bottle comes with a calibrated dosing syringe so each daily dose is drawn accurately without guesswork or measuring tools.
• Selective AT1 Receptor Blockade: Telmisartan selectively blocks the AT1 receptor, reducing angiotensin II-driven vasoconstriction and aldosterone release to lower blood pressure consistently.
• Can Be Added to Food: Unlike many oral medications, Semintra may be placed on top of a small amount of food rather than given directly by mouth, offering flexibility for owners of food-motivated cats.

Ingredients

Active Ingredients

Telmisartan: 10 mg per mL

Inactive Ingredients

Not individually listed in the FDA label for the US 10 mg/mL formulation. The international 4 mg/mL formulation contains benzalkonium chloride as a preservative in a clear viscous solution base.

How to Use

Dosage and Administration Instructions

• Prescription Required: Federal law restricts Semintra to use by or on the order of a licensed veterinarian; always dispense with the Client Information Sheet included.
• Initiating Phase Dose: Give 1.5 mg/kg (0.68 mg/lb) by mouth twice daily for the first 14 days using the included dosing syringe.
• Maintenance Phase Dose: After 14 days, switch to 2 mg/kg (0.91 mg/lb) by mouth once daily for ongoing blood pressure control.
• Dose Reduction for Hypotension: If low blood pressure develops during maintenance, reduce the dose by 0.5 mg/kg (0.23 mg/lb) steps down to a floor of 0.5 mg/kg (0.23 mg/lb) once daily.
• Two Administration Methods: Give directly into the cat's mouth by syringe, or place on top of a small portion of food; do not mix into a full meal as complete dose intake cannot be confirmed.
• Use Included Syringe Only: Always measure each dose using the calibrated syringe provided; household spoons or other measuring devices will not deliver an accurate dose.
• Blood Pressure Monitoring: Measure blood pressure before starting treatment, at the end of the initiating phase, and periodically throughout maintenance to ensure the dose remains appropriate.
• Use Within 6 Months of Opening: Once the bottle seal is broken, the remaining solution must be used within six months; discard any leftover product after this window.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Contraindicated in Telmisartan Hypersensitivity: Do not use Semintra in cats with a known hypersensitivity to telmisartan or any component of the formulation.
• Not Evaluated in Breeding, Pregnant, or Lactating Cats: Semintra has not been studied in breeding, pregnant, or nursing queens; always consult your vet first.
• Kitten Age and Weight: Kittens younger than 6 months or below the 2 kg weight mark fall outside established safety data.
• Pregnant Women Must Avoid Contact: Telmisartan is an ARB drug known to cause serious harm to unborn and newborn humans.
• Monitor for Hypotension Signs: Watch for signs of low blood pressure including weakness, stumbling, or collapse, particularly during the initiating phase or after any dose increase.
• Keep Out of Reach: Store in a secure location away from children and all animals; not for human use.

Possible Side Effects

• Vomiting and Diarrhea: Among cats on Semintra, stomach upset showing up as vomiting or diarrhea tends to be the side effect reported most often in clinical experience.
• Lethargy: Low energy and tiredness have been reported and are among the more frequently noted reactions in cats receiving telmisartan oral solution during clinical trials.
• Weight Loss and Anorexia: Weight loss was a common finding during Semintra field studies; monitor body condition regularly throughout the course of treatment.
• Anemia: A mild drop in red blood cell counts has been seen in some cats on Semintra, which lines up with how telmisartan acts on the RAAS system.
• Dehydration: Dehydration has come up as a side effect in some treated cats; making sure fresh water is always within reach goes a long way during treatment.

Storage Information

• Store at Room Temperature: Short spells in a warmer spot are fine, but keep the solution away from prolonged heat and direct sunlight to hold its stability.
• Use Within 6 Months of Opening: The solution stays good for six months from the day it is first opened; marking that date on the bottle helps keep track.
• Keep Bottle Upright and Closed: Store in an upright position with the cap firmly closed between doses to prevent spillage or contamination of the solution.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is Semintra telmisartan oral solution used for in cats?

Ans: Among prescription options for feline hypertension, Semintra stands alone as the only FDA-approved treatment specifically cleared for this condition in cats. It targets AT1 receptors to ease blood vessel constriction and reduce aldosterone release, bringing blood pressure down steadily when the daily dose is kept consistent as directed by a vet.

Q2: What is the correct Semintra dosing schedule for cats?

Ans: For the first 14 days, the starting dose is 1.5 mg/kg (0.68 mg/lb) given twice a day using the included syringe. From day 15, this shifts to 2 mg/kg (0.91 mg/lb) just once daily. Should low blood pressure become a concern, the vet can step the dose down in 0.5 mg/kg increments until reaching the lowest workable amount of 0.5 mg/kg once daily.

Q3: Can Semintra cat blood pressure solution be mixed into food?

Ans: Semintra can be placed on top of a small portion of food rather than given directly by syringe, which works well for food-motivated cats. It should not be stirred into a full meal, as there is no way to confirm the entire dose was consumed if the cat does not finish the food.

Q4: Can pregnant women handle Semintra telmisartan oral solution?

Ans: No. Telmisartan is an angiotensin receptor blocker that can cause serious fetal and neonatal harm when humans are exposed during pregnancy. Pregnant women must not come into contact with Semintra at any point; another household member should handle dosing and cleaning of the syringe throughout the treatment period.

Q5: How long does an opened bottle of Semintra feline hypertension solution last?

Ans: Semintra oral solution has a six-month use window once opened, so writing the opening date straight onto the label right after first use helps track this easily. Keep it stored at or below 25°C (77°F) with the cap firmly closed between each dose to preserve the solution's integrity throughout that period.