Senergy Topical Solution for Dogs, 20.1-40 lbs, (Red Box)

Senergy Topical Solution for Medium Dogs (20.1–40 lbs)

Senergy Topical Solution for Dogs 20.1–40 lbs is a monthly, prescription-strength parasiticide formulated to protect medium-sized dogs against fleas, heartworms, ear mites, mange, and American dog ticks. The active ingredient, Selamectin, is a broad-spectrum antiparasitic and endectocide that works transdermally to control internal and external parasites. Senergy is a reliable alternative to Revolution for Dogs and offers the same core protection at a more budget-friendly price.

Whether your dog spends time outdoors, at the park, or around other pets, this topical solution helps safeguard their health with one easy, once-a-month application.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Also Available in Other Sizes

Ensure your pet receives the proper protection by selecting the right size of Senergy Topical Solution based on their weight. Explore all available weight-specific options:

• Senergy for Puppies up to 5 lbs – For young pets and toy breeds
  
• Senergy for Dogs 5.1–10 lbs – Ideal for small dogs
• Senergy for Dogs 10.1–20 lbs – For small to medium dogs
• Senergy for Dogs 40.1–85 lbs – Formulated for large dogs
• Senergy for Dogs 85.1–130 lbs – Perfect for extra-large dogs
  

Each formulation delivers the same trusted protection against fleas, heartworms, ear mites, and more—sized just right for your pet's weight and age.

What Are the Benefits of Senergy for Dogs 20.1–40 lbs?

Senergy offers 6-in-1 parasite protection tailored to the needs of medium-breed dogs. Here’s how it exceeds expectations compared to competitor brands:

• Kills adult fleas and prevents flea eggs from hatching for one full month

• Prevents heartworm disease caused by Dirofilaria immitis

• Treats and controls ear mites (Otodectes cynotis)

• Treats sarcoptic mange (Sarcoptes scabiei) infections

• Kills American dog ticks (Dermacentor variabilis)

• Water-resistant after 2 hours of application

• Vet-recommended with proven bioavailability and safety profile

• Alternative to Revolution at lower cost

How Does Senergy Topical Solution Work?

Senergy's primary ingredient, Selamectin, is absorbed through the skin and distributed systemically via the bloodstream. It targets the nervous system of parasites, causing paralysis and death. This mechanism makes it effective against both internal parasites (like heartworms) and external parasites (like fleas and mites).

How to Use Senergy for Medium Dogs?

Always consult your veterinarian for exact dosage instructions depending on your pet's condition.

• Use only on dogs weighing 20.1 to 40 lbs and at least 6 weeks of age

• Apply one full unit-dose tube topically once a month

• Part the hair at the base of the neck and apply the entire contents directly to the skin

• Do not massage or spread by hand

• Avoid bathing or swimming within 2 hours of application

What Are the Active Ingredients in Senergy for Dogs?

Each unit dose tube of Senergy Topical Solution contains:

Selamectin belongs to the macrocyclic lactone class of antiparasitic agents. It binds to glutamate-gated chloride channels in nerve and muscle cells of parasites, disrupting neural signals and causing paralysis and death.

Are There Any Side Effects of Senergy for Dogs?

While generally well-tolerated, some dogs may experience mild and temporary side effects:

• Itching or hair loss at application site

• Digestive upset (vomiting or diarrhea)

• Lethargy

• Drooling (if ingested accidentally)

Seek veterinary attention if symptoms persist or worsen.

What Warnings Should Pet Owners Be Aware Of?

• Not for use in puppies under 6 weeks of age

• Do not use on sick, debilitated, or underweight dogs

• Avoid contact with human skin and wash hands after application

• Keep out of reach of children and other pets until dry

• Safe for breeding, pregnant, and lactating dogs as per veterinary guidance

Shipping & Returns

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Senergy Topical Solution for Medium Dogs FAQs 

What is Senergy Topical Solution used for?

Senergy treats and prevents fleas, heartworms, ear mites, sarcoptic mange, and American dog ticks in dogs weighing 20.1–40 lbs.

Is Senergy as effective as Revolution for Dogs?

Yes, Senergy contains the same active ingredient—Selamectin—as Revolution and provides equivalent 6-in-1 protection at a lower cost.

How long does it take for Senergy to work?

Fleas begin to die within 36 hours, and protection against heartworms and mites begins within 72 hours after application.

Can Senergy be used on pregnant or lactating dogs?

Selamectin-based products like Senergy are generally considered safe during pregnancy and lactation, but consult your vet before use.

What if I miss a dose of Senergy for my dog?

Apply the missed dose as soon as you remember, and continue monthly treatments. Avoid double dosing to compensate for a missed application.

High-Authority Medical Resources

• Selamectin (Active Ingredient): FDA substance profile detailing.
• Heartworm Disease : Educational overview from the American Heartworm Society
• Sarcoptic Mange : Veterinary guide by MSD