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Sentinel Flavor Tabs for Dogs 26-50 lbs

$60.99

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Prescription Required

Merck Animal Health SKU: 333731-MER Barcode: 716688522313

Size (Count): 6 Tablets
Free Shipping on Prescription Pharmacy orders above $49

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Sentinel Flavor Tabs for Medium Dogs 26-50 lbs (6-Month Supply)

Sentinel Flavor Tabs for Dogs 26-50 lbs is a monthly oral prescription medication specifically designed to protect medium-sized dogs from heartworm disease, flea infestations, and common intestinal parasites. This chewable tablet, flavored with pork liver and soy protein, is easy to administer and well-accepted by dogs.

Combining the active ingredients milbemycin oxime and lufenuron, Sentinel offers broad-spectrum parasite prevention by:

  • Killing heartworm larvae before they mature
  • Controlling adult roundworms, hookworms, and whipworms
  • Preventing flea eggs from hatching—thus breaking the flea lifecycle

It is an all-in-one, veterinarian-recommended solution that simplifies your pet’s parasite protection plan.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.

Also Available in Other Weight Ranges

Looking for the right dosage for your dog's weight? Sentinel Flavor Tabs are available in a range of strengths to ensure accurate protection based on size:

Choose the correct strength for complete parasite protection tailored to your dog’s weight.

What Are the Benefits of Sentinel Flavor Tabs for Dogs 26-50 lbs?

Sentinel provides multiple advantages over standalone heartworm or flea treatments:

  • Protects against 5 major parasites: Heartworms, hookworms, roundworms, whipworms, and flea infestations
  • Flea prevention without harsh chemicals: Lufenuron stops flea egg development instead of attacking adult fleas
  • Highly palatable tablet: Pork-liver flavor for easy acceptance
  • Once-monthly dosing: Hassle-free administration—no messy topicals or collars
  • Safe for homes with children or other pets: No chemical residue left on your pet
  • Ideal for year-round or seasonal use based on your region

How to Properly Give Sentinel Flavor Tabs to Your Dog? (Dosage and Administration)

Always consult your veterinarian before starting any parasite prevention regimen.

🐶 Recommended Dosage:

  • Dogs 26–50 lbs: 1 Yellow Box tablet once per month
  • For dogs over 100 lbs, combine appropriate tablet strengths

💊 Administration Guidelines:

  • Give orally once a month, on the same day each month
  • Must be given with a full meal to ensure proper absorption
  • Tablets may be offered by hand or hidden in food
  • Monitor to ensure full ingestion; re-dose if tablet is not fully consumed

If more than 30 days pass between doses, administer immediately and resume monthly schedule. Re-test for heartworms after 6 months if lapses occur.

What Ingredients Are in Sentinel Flavor Tabs and What Do They Do?

Active Ingredient

Purpose

Milbemycin Oxime

Kills developing heartworm larvae; treats roundworms, hookworms, whipworms

Lufenuron

Prevents flea eggs from hatching; breaks flea life cycle

Are There Any Side Effects of Sentinel Flavor Tabs?

While Sentinel is generally well tolerated, possible side effects include:

  • Vomiting or diarrhea
  • Lethargy or drowsiness
  • Loss of appetite
  • Itching or hives
  • Rare cases: seizures or hypersalivation

If side effects occur, contact your veterinarian immediately.

What Warnings Should Pet Owners Be Aware Of?

  • Dogs must test negative for heartworms before starting Sentinel.
  • Not intended for use in cats or humans.
  • Use caution if your dog is on concurrent medications, especially:
    • Cyclosporine, azole antifungals, verapamil, and others (see drug interaction list below)
  • Sentinel is safe for MDR1-sensitive breeds, but always consult your vet if unsure
  • Store between 59°F and 77°F (15-25°C) in a dry place

Drug Interactions: What Should You Avoid While Using Sentinel?

Avoid concurrent administration with other heartworm preventives or medications that inhibit P-glycoprotein, such as:

  • Amiodarone
  • Erythromycin / Clarithromycin
  • Ketoconazole
  • Cyclosporine
  • Spironolactone
  • Diltiazem / Verapamil

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Sentinel Flavor Tabs for Dogs 26-50 lbs FAQs 

What is Sentinel used for in dogs?

Sentinel protects dogs from heartworm disease, treats roundworms, hookworms, whipworms, and prevents flea eggs from developing into adults.

How long does Sentinel take to work?

It begins working within hours, immediately disrupting the flea life cycle and eliminating immature heartworms and intestinal parasites.

Can Sentinel be given to puppies or pregnant dogs?

Sentinel is safe for puppies 4+ weeks old and over 2 lbs. Consult your vet before use in pregnant or lactating dogs.

What if I miss a dose of Sentinel?

Administer the missed dose immediately and continue on your regular schedule. A heartworm test may be needed after 6 months if there’s a significant lapse.

Does Sentinel kill adult fleas?

No. Sentinel prevents flea infestations by stopping eggs from hatching. Use an adulticide alongside if adult fleas are present.

Authoritative Resource Links:

  1. American Heartworm Society – Heartworm Lifecycle
  2. Drugs.com – Milbemycin Oxime + Lufenuron
  3. FDA Sentinel Approval Information

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