Tri-Heart Plus Chewable Tablet for Dogs 26-50lbs

Tri-Heart Plus for Dogs, 26-50 lbs

Monthly Protection Against Heartworms & Intestinal Parasites

Tri-Heart Plus for Dogs (26-50 lbs) is a veterinarian-recommended, broad-spectrum preventative medication designed to protect your medium-sized dog against the dangers of heartworm disease, hookworms, and roundworms. Each once-a-month chewable tablet contains a precise combination of Ivermectin and Pyrantel, two powerful antiparasitic agents that work synergistically to break the lifecycle of harmful parasites, keeping your pet safe, active, and parasite-free.

Ideal for dogs weighing between 26 and 50 pounds, Tri-Heart Plus is a trusted alternative to brands like Heartgard, offering the same protection at a more affordable price—without compromising on quality or effectiveness.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Also Available in Other Weight Ranges

Tri-Heart Plus is available in multiple weight-specific formulas to ensure accurate dosing and maximum parasite protection for dogs of all sizes:

• Tri-Heart Plus for Small Dogs – Up to 25 lbs : Perfect for small breeds and puppies needing gentle yet effective monthly protection. 
• Tri-Heart Plus for Medium Dogs – 26 to 50 lbs : ideal for medium-sized dogs.   (You're currently viewing this product)
• Tri-Heart Plus for Large Dogs – 51 to 100 lbs : Designed for large breeds needing high-dosage, broad-spectrum worm prevention.

Choose the formula that matches your dog’s weight for consistent, vet-recommended parasite protection.

What Are the Benefits of Tri-Heart Plus for Medium Dogs, 26-50 lbs?

Tri-Heart Plus offers a suite of key benefits that address the most pressing concerns for pet parents:

• Prevents deadly heartworm disease, which is transmitted through mosquito bites
  
• Treats and controls intestinal parasites including adult hookworms (Ancylostoma caninum, Uncinaria stenocephala) and roundworms (Toxocara canis, Toxascaris leonina)
  
• Affordable monthly protection comparable in effectiveness to more expensive brands like Heartgard Plus
  
• Beef-flavored chewable is easy to administer and highly palatable for dogs
  
• Safe for dogs as young as 6 weeks old, with no known breed restrictions
  
• Veterinarian-approved and EPA regulated for quality and safety
  

How Do I Know If My Dog Needs Heartworm Prevention?

Many pet parents ask this before their first purchase. This section targets that awareness-stage query.

• Heartworm disease is often silent in early stages—by the time symptoms appear, it's already severe.
  
• If your dog spends time outdoors, even briefly, they’re exposed to mosquito bites.
  
• Prevention with Tri-Heart Plus is safer, easier, and far less expensive than treating advanced heartworm disease.
  
• Even indoor dogs are at risk—mosquitoes can enter homes easily.
  

Dosage and Administration for Tri-Heart Plus (26-50 lbs)

Always consult your veterinarian for exact dosage instructions depending on your pet's condition.

• Dosage: One tablet monthly for dogs weighing 26-50 lbs
  
• Administration: Give orally with or without food
  
• Consistency is key: Administer on the same day every month
  
• Missed a dose? Give it as soon as you remember, then continue regular schedule
  

What Ingredients Are in Tri-Heart Plus for Medium Dogs?

Each chewable tablet contains:

• Ivermectin (136 mcg): Kills the larvae of heartworms (Dirofilaria immitis) before they mature
  
• Pyrantel Pamoate (114 mg): Treats and eliminates intestinal parasites like hookworms and roundworms
  
• Inactive Ingredients: Artificial beef flavoring and excipients for chewable formulation
  

This combination interrupts parasite lifecycles both internally and externally, offering full-spectrum protection year-round.

Why Pet Parents Choose Tri-Heart Plus from HardyPaw

• Same trusted formulation as leading brands like Heartgard—at a better price
• Fast, reliable shipping to ensure your dog never misses a dose
  
• Dedicated support to help you with dosage, administration, and reminders
  
• Curated vet-recommended brands that meet our high standards of pet health
  

Are There Any Side Effects of Tri-Heart Plus for Dogs?

While Tri-Heart Plus is generally well-tolerated, occasional side effects may include:

• Lethargy
  
• Vomiting or diarrhea
  
• Loss of appetite
  
• Trembling or seizures (in rare cases with ivermectin sensitivity)
  

⚠️ Dogs with the MDR1 gene mutation (common in Collies, Australian Shepherds) may be more sensitive to ivermectin. Consult your vet if you're unsure.

What Warnings or Precautions Should I Know?

• For canine use only
  
• Keep out of reach of children and pets
  
• Do not administer to cats
  
• Store in a cool, dry place, away from direct sunlight
  
• Use in heartworm-negative dogs only—testing is required prior to first use
  
• Regular vet check-ups and annual heartworm tests are recommended
  

Tips to Never Miss a Monthly Dose

Compliance is one of the biggest issues with heartworm meds. Helping users stay consistent is valuable.

• Set a monthly reminder on your phone/calendar
  
• Align dosing with another monthly activity (e.g., flea/tick prevention)
  
• Use HardyPaw’s auto-ship feature (if available) so doses arrive just in time
  
• Keep tablets in a visible spot, like near your dog's treats or food
  

Shipping & Returns

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Tri-Heart Plus for Medium Dogs 26-50 lbs FAQs 

Can Tri-Heart Plus be given with other medications?

Tri-Heart Plus can be administered with most flea, tick, and routine medications. Veterinary guidance is recommended to ensure no interactions occur with other treatments or supplements.

Does Tri-Heart Plus protect against whipworms or tapeworms?

Tri-Heart Plus does not protect against whipworms or tapeworms. It targets heartworms, hookworms, and roundworms. Additional dewormers may be needed for full-spectrum parasite control.

Is a prescription required to buy Tri-Heart Plus for dogs?

Yes, a valid veterinary prescription is required to purchase Tri-Heart Plus. The product contains ivermectin, which must be used under veterinary supervision to ensure safety and effectiveness.

How long does it take for Tri-Heart Plus to start working?

Tri-Heart Plus begins working immediately upon ingestion, killing immature heartworm larvae and targeting existing intestinal worms within hours. Monthly use maintains continuous protection.

Can Tri-Heart Plus be used in dogs with food allergies?

Tri-Heart Plus contains beef-based flavoring, which may trigger reactions in dogs with beef allergies. Ask your vet for allergy-friendly alternatives if your dog has dietary sensitivities.

Clinical Research

• https://www.msdvetmanual.com/dog-owners/digestive-disorders-of-dogs/gastrointestinal-parasites-of-dogs
• https://www.petmd.com/pet-medication/pyrantel-pamoate
• https://www.fda.gov/safety/medical-product-safety-information/ivermectin-intended-animals-letter-stakeholders-do-not-use-humans-treatment-covid-19