Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Monthly Heartworm & Intestinal Parasite Prevention for Medium Dogs (26–50 lbs)
Product Description
Tri-Heart Plus Chewable Tablets (Green Box) are a prescription, once-monthly oral treatment for dogs weighing between 26 and 50 pounds. Each beef-flavored tablet pairs Ivermectin and Pyrantel to prevent heartworm disease and clear roundworm and hookworm infections in one simple monthly dose. Recognised as the number one generic alternative to Heartgard Plus, it carries the same active ingredients at identical strengths while coming in at a more budget-friendly price. Safe for dogs and puppies from six weeks of age.
Benefits
- Heartworm Disease Prevention: Clears the tissue stage of heartworm larvae (Dirofilaria immitis) within 30 days of infection, stopping worms before they reach your dog's heart.
- Treats Roundworms: Works against Toxocara canis and Toxascaris leonina roundworm species, keeping these widespread intestinal parasites away from medium dog breeds.
- Treats Hookworms: Addresses three hookworm species including Ancylostoma caninum, Uncinaria stenocephala, and Ancylostoma braziliense for well-rounded intestinal parasite coverage.
- Easy to Give: Formulated as a beef-flavored chewable that most dogs take without hesitation, keeping the monthly routine smooth and stress-free for owners.
- Puppy Friendly: Can be given to puppies as young as six weeks old with no upper age cap, covering dogs right through to their senior years.
- Cost-Effective Alternative: Packs the same active ingredients at identical strengths as Heartgard Plus, bringing equivalent protection at a noticeably lower cost.
- Backed by a Guarantee: Used year-round as directed, this product is covered by the manufacturer's guarantee including diagnostic costs and a free one-year supply if a heartworm positive result comes back.
Ingredients
Composition Table
| Ingredient | Quantity (per tablet, 26–50 lb dogs) |
| Ivermectin | 136 mcg |
| Pyrantel (as pamoate salt) | 114 mg |
How to Use
Dosage & Administration Instructions
- Prescription Required: This product is available on prescription only and must be obtained through or under the direct order of a licensed veterinarian.
- Monthly Oral Dose: Give one full chewable tablet to your dog on the same date every month to keep heartworm and intestinal parasite protection running without gaps.
- How to Offer the Tablet: The tablet can be handed over directly, placed into a small portion of dry food, or positioned at the back of the mouth for dogs that need a little more encouragement.
- One Tablet at a Time: Take a single tablet out of the blister card just before giving it, as the sealed packaging keeps the tablet safe from air and light until use.
- Minimum Dose: Each monthly dose should deliver at least 6 mcg of Ivermectin per kilogram and 5 mg of Pyrantel per kilogram of your dog's body weight.
- Seasonal Use: When dosing only during mosquito season, the opening dose should be given within 30 days of your dog's first mosquito exposure of the season.
- Missed Dose: Give the missed dose the moment you notice and pick up the monthly schedule from there; reach out to your vet if more than 30 days have passed between doses.
- Set a Reminder: Sign up for free monthly email reminders from the manufacturer or use the reminder stickers found inside each pack to keep dosing on track.
Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any medication for your pet.
Additional Information
Precautions
- Heartworm Screening First: A heartworm test should be done with your vet before the first tablet is given, as this product is not built to handle heartworm infections that are already established.
- Not for Heartworm-Positive Dogs: Dogs already carrying heartworms need to go through proper treatment to clear adult worms and microfilariae before this product can be started.
- Dogs Only: This product has not been approved for cats and must never be handed over to them under any circumstances.
- Herding Breed Caution: Some herding breeds like Collies and Australian Shepherds may carry the MDR1 gene mutation, which can lead to sensitivities to ivermectin; always check with your vet first.
- No Double Preventives: This tablet should not be given at the same time as any other heartworm preventive; only one product should be in use at a time.
- Breeding Females: A full safety assessment for pregnant and nursing dogs has not been completed; always get veterinary guidance before treating females in either of these stages.
- Check Before Giving: Once the date on the packaging has been and gone, the tablet inside should be discarded rather than given to your dog.
- Intact Blister Pack Only: If the foil on the blister card looks peeled back, punctured, or damaged in any way, do not use the tablet as its protective seal has been broken.
Possible Side Effects
- Digestive Upset: Vomiting, loose stools, a drop in appetite, and excessive drooling have been reported in a small proportion of dogs following their monthly tablet.
- Neurological Reactions: Less commonly, dogs may show signs of low mood, poor coordination, unsteady movement, dilated pupils, or convulsions after receiving ivermectin.
- Overdose Risk: Doses above the recommended level may bring on tremors, significant weight loss, dilated pupils, or in severe situations, life-threatening outcomes; contact your vet immediately if an overdose is suspected.
Storage Information
- Room Temperature Storage: A consistent indoor location sitting between 59°F (15°C) & 86°F (30°C) is the right place to keep this product stored properly.
- Protect from Light: Leave the tablets inside their original blister packaging and out of direct light right up until the moment they are needed.
- Safe Storage Practice: Keep this prescription tablet well out of reach of children and other household animals to remove any risk of accidental ingestion.
Shipping & Return
We offer ground, express, and priority delivery; see our shipping policy for details.
For return instructions or product concerns, please refer to our detailed refund policy.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Frequently Asked Questions
Q1: What does Tri-Heart Plus (Green Box) treat in medium dogs?
Ans: Tri-Heart Plus (Green Box) prevents heartworm disease and treats roundworms including Toxocara canis and Toxascaris leonina, and hookworms including Ancylostoma caninum, Uncinaria stenocephala, and Ancylostoma braziliense. It does not cover whipworms or tapeworms in medium dogs.
Q2: Is Tri-Heart Plus the same as Heartgard Plus for medium dogs?
Ans: Both products carry Ivermectin and Pyrantel at matching strengths, making Tri-Heart Plus a direct generic equivalent. The level of parasite protection delivered is identical across both. A palatability study showed dogs showed no preference between the two products during testing.
Q3: Can Tri-Heart Plus be given to a medium dog that already has heartworms?
Ans: No. This product is not designed to clear active heartworm infections. Dogs confirmed as heartworm positive must go through full treatment to remove adult worms and microfilariae under veterinary supervision before this tablet can be used as a monthly preventive.
Q4: What should I do if I miss a monthly dose of Tri-Heart Plus for my medium dog?
Ans: Give the missed dose the moment you notice and continue the regular monthly schedule from there. Never double up. If more than 30 days have passed, get in touch with your vet, as a follow-up heartworm test may be recommended before carrying on with the program.
Q5: Is Tri-Heart Plus safe for pregnant or nursing medium dogs?
Ans: Ivermectin and Pyrantel show a wide margin of safety at the recommended dose, including in pregnant females and breeding males. That said, full safety studies for pregnant and nursing dogs have not been completed, so always check with your vet before giving this product to a female in either of these stages.