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Trifexis Chewble Tablets for Dogs (Spinosad + Milbemycin Oxime) 20.1-40 lbs

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$23.24

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Elanco SKU: CA4334Y07AM-1 Barcode: 727804562250

Size: 1 Chewable Tablet (1 Month Supply)

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Trifexis for Dogs 20.1-40 lbs

All-in-One Flea, Heartworm & Intestinal Parasite Protection

Trifexis for Dogs 20.1-40 lbs is a powerful monthly chewable tablet designed to protect medium-sized dogs from fleas, heartworms, and intestinal parasites. This broad-spectrum parasite preventative combines spinosad and milbemycin oxime to kill fleas, prevent heartworm disease, and eliminate intestinal worms like roundworms, hookworms, and whipworms.

With just one easy-to-administer tablet per month, Trifexis ensures your dog stays protected against multiple parasites with a single dose, eliminating the need for separate medications.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Please note product may arrive in a HardyPaw Pharmacy vial, manufacturer packaging is shown for reference.

Also Available in Different Weight Ranges

Trifexis is available in multiple dosage strengths to ensure the best protection for dogs of all sizes. Choose the right option based on your dog's weight:

📌 Trifexis for Dogs 5-10 lbs (Magenta)
📌 Trifexis for Dogs 10.1-20 lbs (Orange)
📌 Trifexis for Dogs 20.1-40 lbs (Green)  (you are viewing this product)
📌 Trifexis for Dogs 40.1-60 lbs (Blue)
📌 Trifexis for Dogs 60.1-120 lbs (Brown)  

Ensure your dog gets the correct Trifexis dosage based on their weight for optimal protection against fleas, heartworms, and intestinal parasites! 🐶💊

What Are the Benefits of Trifexis for Dogs 20.1-40 lbs?

  • Fast-Acting Flea Protection – Starts killing fleas within 30 minutes and eliminates infestations before they lay eggs.
  • Heartworm Disease Prevention – Prevents deadly heartworm infections caused by mosquito bites.
  • Broad-Spectrum Dewormer – Kills and controls roundworms, hookworms, and whipworms to maintain gut health.
  • Convenient Once-a-Month Dosing – No messy topical treatments or collars—just a simple chewable tablet.
  • Beef-Flavored for Easy Administration – Tasty chew makes dosing stress-free for pet owners and dogs alike.
  • No Bathing or Swimming Restrictions – Since it’s an oral tablet, there’s no waiting period after administration.

How Does Trifexis for Dogs Work?

Trifexis contains two powerful active ingredients:

Ingredient

Function

Spinosad

Kills fleas by disrupting their nervous system, leading to paralysis and death.

Milbemycin Oxime

Prevents heartworm disease and eliminates intestinal parasites by interfering with nerve transmission in parasites.

By combining these two active ingredients, Trifexis delivers comprehensive parasite protection, ensuring your dog stays flea-free and safeguarded against life-threatening diseases.

How to Administer Trifexis for Dogs 20.1-40 lbs?

  • Give one chewable tablet per month with food for maximum effectiveness.
  • Ensure your dog consumes the entire tablet to receive the full dose.
  • If vomiting occurs within an hour of administration, consult your veterinarian to determine if a replacement dose is needed.
  • Maintain a consistent monthly schedule to ensure continuous protection.

Always consult your veterinarian for the best dosing schedule based on your dog’s health and lifestyle.

How to Tell If Your Dog Has Fleas, Worms, or Heartworms?

Educate pet owners on common signs of infestations:

🐜 Flea Infestation Symptoms:

  • Excessive scratching or biting
  • Red, irritated skin
  • Flea dirt (tiny black specks)

🪱 Intestinal Worm Symptoms:

  • Potbelly appearance
  • Weight loss
  • Diarrhea or vomiting
  • Visible worms in stool

🫀 Heartworm Disease Symptoms:

  • Persistent coughing
  • Fatigue after exercise
  • Difficulty breathing
  • Swollen belly (fluid buildup)

Encouraging early detection can drive urgency for purchasing Trifexis.

What Are the Side Effects of Trifexis for Dogs 20.1-40 lbs?

While Trifexis is generally well-tolerated, some dogs may experience mild side effects, including:

  • Vomiting
  • Lethargy
  • Diarrhea
  • Decreased appetite
  • Itching or redness

If severe reactions such as seizures, excessive drooling, or difficulty breathing occur, seek veterinary assistance immediately.

What Precautions Should You Take When Using Trifexis?

 Not for Puppies Under 8 Weeks or Under 5 lbs – Use only on dogs within the recommended weight range.
 Not for Breeding, Pregnant, or Lactating Dogs – Consult a veterinarian before use.
 Monitor for Adverse Reactions – Especially during the first dose.
 Keep Away from Cats – Trifexis is specifically formulated for dogs and may be harmful to cats.
 Year-Round Use Recommended – Consistent monthly dosing is necessary to prevent heartworm disease effectively.

Environmental Flea Control Tips

To maximize flea prevention, treat your dog's environment:

  • Wash bedding & vacuum carpets weekly.
  • Use flea sprays or foggers for the home.
  • Keep outdoor areas trimmed to reduce flea habitats.

How to Store Trifexis Correctly?

  • Store at room temperature (68°F to 77°F).
  • Keep away from moisture and direct sunlight.
  • Do not refrigerate.
  • Keep out of reach of children and pets.

Subscription & Auto-Refill Benefits

🔔 Never Miss a Dose! Subscribe & Save on Trifexis with HardyPaw for automatic deliveries & exclusive discounts.

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Trifexis for Dogs 20.1-40 lbs FAQs

How long does Trifexis take to work on fleas?

Trifexis begins killing fleas within 30 minutes and eliminates 100% of adult fleas within 4 hours.

Can I use Trifexis and another flea treatment together?

Trifexis is highly effective on its own. If additional flea control is needed, consult your veterinarian before combining treatments.

Does Trifexis protect against ticks?

No, Trifexis does not provide tick protection. If tick control is needed, discuss complementary tick preventatives with your vet.

Can my dog go swimming after taking Trifexis?

Yes! Since Trifexis is an oral tablet, water activities like swimming and bathing do not affect its efficacy.

What happens if I miss a dose of Trifexis?

Administer the missed dose immediately and resume your regular schedule. Delayed dosing can increase the risk of heartworm infection.

High Authority References:

🔗 Understanding Heartworm Disease  American Heartworm Society

🔗 Flea Lifecycle & Prevention  American Veterinary Medical Association (AVMA)

🔗 Pet Parasite Prevention Guide  Companion Animal Parasite Council (CAPC)

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