Trifexis Chewable Tablets for Dogs 60.1-120 lbs (Spinosad + Milbemycin Oxime)

Trifexis for Large Dogs 60-120 lbs

All-in-One Flea, Heartworm & Intestinal Parasite Protection

What is Trifexis for Dogs 60-120 lbs?

Trifexis for Dogs 60-120 lbs is a veterinary-recommended, broad-spectrum parasite protection that safeguards large dogs from fleas, heartworm disease, and common intestinal worms. This beef-flavored, chewable tablet combines spinosad and milbemycin oxime, two potent active ingredients that kill fleas and prevent infestations while also protecting against heartworms, roundworms, hookworms, and whipworms.

With once-a-month dosing, Trifexis offers pet owners a convenient, all-in-one parasite control solution without the hassle of topical applications. This makes it ideal for active dogs, water-loving breeds, and households with children, as there is no risk of chemical transfer through touch.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Please note product may arrive in a HardyPaw Pharmacy vial, manufacturer packaging is shown for reference.

Also Available in Different Weight Ranges

Trifexis is available in multiple dosage strengths to ensure the best protection for dogs of all sizes. Choose the right option based on your dog's weight:

📌 Trifexis for Dogs 5-10 lbs (Magenta)
📌 Trifexis for Dogs 10.1-20 lbs (Orange)
📌 Trifexis for Dogs 20.1-40 lbs (Green)
📌 Trifexis for Dogs 40.1-60 lbs (Blue)
📌 Trifexis for Dogs 60.1-120 lbs (Brown) - (you are viewing this product)

Ensure your dog gets the correct Trifexis dosage based on their weight for optimal protection against fleas, heartworms, and intestinal parasites! 🐶💊

What Are the Benefits of Trifexis for Dogs 60-120 lbs?

• Trifexis is a comprehensive parasite defense formulated to offer multiple benefits:
• Fast-Acting Flea Control – Starts killing fleas within 30 minutes and eliminates 100% of adult fleas within 4 hours.
• Prevents Heartworm Disease – Monthly protection against potentially fatal heartworm infections transmitted by mosquitoes.
• Treats & Controls Intestinal Worms – Kills roundworms, hookworms, and whipworms, reducing risks of malnutrition and digestive issues.
• Easy Oral Administration – No messy topical application; just give as a flavored chew.
• Waterproof Protection – No need to restrict bathing or swimming, unlike topical treatments.
• Veterinarian-Recommended – Safe and effective for large dogs within the 60-120 lbs weight range when used as directed.

How to Administer Trifexis for Large Dogs?

To ensure optimal protection, follow these dosage guidelines:

• Give one tablet orally once a month with food for maximum absorption.
• Ensure your dog consumes the full dose to maintain efficacy.
• Administer on the same day each month for consistent protection.
• If your dog vomits within an hour of administration, redose with a full tablet.

💡 Always consult your veterinarian for personalized dosage recommendations based on your dog's health and lifestyle.

What Are the Active Ingredients in Trifexis?

These ingredients work together to provide a complete parasite protection solution, making Trifexis a trusted choice for dog owners.

Are There Any Side Effects of Trifexis?

While Trifexis is generally well-tolerated, some dogs may experience:

• Mild digestive upset (vomiting, diarrhea, or decreased appetite)
• Lethargy or temporary drowsiness
• Itching or skin sensitivity (rare)

🐾 If your dog exhibits severe reactions such as seizures, persistent vomiting, or difficulty breathing, contact your veterinarian immediately.

Important Safety Warnings for Trifexis

• For dogs 8 weeks of age and older, weighing at least 5 lbs.
• Not recommended for dogs with a history of seizures.
• Requires a negative heartworm test before starting treatment.
• Avoid use in pregnant or breeding females without veterinary approval.
• Keep out of reach of children and store at room temperature.

💡 Always consult your veterinarian before introducing any new medication to your pet.

Storage & Handling Instructions

• Store at room temperature (68-77°F / 20-25°C).
• Keep tablets in their original packaging to maintain effectiveness.
• Do not use expired medication.

Environmental Flea Control Tips 

To maximize flea prevention, treat your dog's environment:

• Wash bedding & vacuum carpets weekly.
• Use flea sprays or foggers for the home.
• Keep outdoor areas trimmed to reduce flea habitats.

Subscription & Auto-Refill Benefits

🔔 Never Miss a Dose! Subscribe & Save on Trifexis with HardyPaw for automatic deliveries & exclusive discounts.

Shipping & Returns 

Shipping Policy: HardyPaw offer all types of shipping options (Ground, Express, Priority, International) depending on the urgency of the product requirements. To know about our shipping policy in detail, click here.

Refund policy: If you face any issue with our product and want to return it, read our refund policy carefully.

Trifexis for Dogs 60-120 lbs - FAQs

What is Trifexis used for?

Trifexis is used to prevent heartworm disease, kill fleas, and treat roundworms, hookworms, and whipworms in dogs weighing 60-120 lbs.

How fast does Trifexis work?

Trifexis begins killing fleas within 30 minutes, with 100% flea elimination within 4 hours after ingestion.

Can I give Trifexis to my dog without food?

It is recommended to administer Trifexis with food to enhance absorption and effectiveness.

 What happens if I miss a dose of Trifexis?

Give the missed dose as soon as possible, then continue monthly dosing. If a long gap occurs, consult your vet before restarting.

Can Trifexis be used alongside other medications?

Trifexis is generally safe with most medications, but always inform your veterinarian about any supplements or treatments your dog is taking.

What happens if my dog throws up after taking Trifexis?

If vomiting occurs within 1 hour, redose with a full tablet. If vomiting continues, consult your vet.

Can I give Trifexis and a tick medication together?

Yes, since Trifexis does not cover ticks, it can be safely combined with Bravecto, NexGard, or Simparica for full protection.

Is Trifexis safe for pregnant or nursing dogs?

Trifexis has not been tested in breeding, pregnant, or lactating dogs. Consult your vet before use.

Can Trifexis be split in half?

No, Trifexis should never be split or crushed, as it affects dosing accuracy.

High Authority References:

🔗 Understanding Heartworm Disease – American Heartworm Society

🔗 Flea Lifecycle & Prevention – American Veterinary Medical Association (AVMA)

🔗 Pet Parasite Prevention Guide – Companion Animal Parasite Council (CAPC)