Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99
Product title
Vendor
$19.99 | $24.99

Once-Daily Antibiotic Powder for Bacterial Infections in Horses
Product Description
Uniprim Powder is an FDA-approved prescription oral antibiotic for horses containing trimethoprim and sulfadiazine. It works by blocking two separate steps in the way bacteria produce folic acid, cutting off a key nutrient they need to grow and survive. The powder is top-dressed on feed once daily, removing the need for injections or multiple daily doses. It is safe for foals, manufactured in the USA, and available in unflavored and apple flavor across multiple container sizes.
Benefits
- Dual Antibacterial Action: Trimethoprim and sulfadiazine each target a different step in bacterial folic acid production, making the combination more effective against susceptible organisms.
- Treats Respiratory Infections: Indicated for systemic antibacterial action against respiratory tract infections caused by susceptible bacteria in horses and foals.
- Treats Acute Strangles: Effective for treating and controlling acute strangles caused by Streptococcus equi in horses requiring strong systemic antibacterial coverage.
- Treats Wounds and Abscesses: Indicated for wound infections and abscesses in horses that need reliable systemic antibacterial support to clear the infection.
- Treats Urogenital Infections: Covers acute urogenital infections in horses requiring systemic control against susceptible bacterial organisms.
- Safe for Foals: Well tolerated by foals at the recommended dose, with no harmful effects on stallion spermatogenesis observed during clinical studies.
- Once-Daily Top-Dressing: Given just once a day mixed into a small amount of feed, making it a straightforward and stress-free treatment option for horse owners.
Ingredients
Active Ingredients
Trimethoprim 67mg, Sulfadiazine 333mg per gram
How to Use
Uniprim Powder for Horses is a prescription-only medication. Federal law restricts this product to use by or on the order of a licensed veterinarian, and a valid prescription is required to purchase it.
Please follow your veterinarian's specific instructions for dosage, preparation, and duration of treatment for your horse.
Disclaimer: Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet.
Additional Information
Precautions
- Contraindicated in Liver Disease: Uniprim must not be given to horses with significant liver damage, as trimethoprim and sulfadiazine are contraindicated in these animals.
- Avoid in Blood Disorders: Do not use in horses with blood dyscrasias, as suppression of blood cell production is a documented risk with high or prolonged use of this medication.
- Not for Sulfonamide-Sensitive Horses: Horses with a known history of sensitivity or allergy to sulfonamide-based medications must not receive this product.
- Blood Monitoring for Long-Term Use: Extended treatment requires periodic platelet and blood cell counts to catch any early signs of hematopoietic changes in the horse.
- Caution in Pregnant Mares: The effect of this medication on equine pregnancy has not been fully studied; use only under direct veterinary guidance in pregnant mares.
- Not for Horses Intended for Human Consumption: This product must not be used in any horse intended to enter the human food supply at any point.
- Secure Storage Required: Lock this product away somewhere children, dogs, cats, and other household animals simply cannot get into.
Possible Side Effects
- Reduced Appetite: One case of anorexia was noted during clinical trials; keep an eye on feed intake throughout the full treatment course.
- Loose Feces or Diarrhea: Loose stools were reported in clinical trials and diarrhea has been noted post-approval; in some cases this can be potentially serious.
- Hypersensitivity Reactions: Some horses may show local or generalised allergic reactions to this medication; rare anaphylactoid reactions have also been reported.
- Blood Cell Suppression: High or prolonged doses can mildly reduce blood cell production; this is reversible when the medication is stopped or folinic acid is given.
Storage Information
- Store at Room Temperature: Keep Uniprim Powder tucked away from moisture and direct sunlight in a consistently dry spot to maintain its condition.
- Secure Storage Required: This product must be kept somewhere completely inaccessible to children, dogs, cats, and any other animals in the household.
NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.
Shipping & Return
We offer ground, express, and priority delivery; see our shipping policy for details.
For return instructions or product concerns, please refer to our detailed refund policy.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Frequently Asked Questions
Q1: What bacterial infections does Uniprim Powder treat in horses?
Ans: Uniprim covers a solid range of bacterial conditions in horses, including respiratory tract infections, acute strangles, wound infections, abscesses, and urogenital infections. It can be used on its own or alongside intravenous trimethoprim-sulfadiazine therapy when your vet determines that combined treatment is the right approach.
Q2: How does Uniprim Powder work against bacterial infections in horses?
Ans: Uniprim takes a two-pronged approach by blocking two separate steps in the way bacteria produce folic acid, a nutrient they need to survive and multiply. Hitting both steps together makes it significantly harder for susceptible bacteria to develop resistance or work around the treatment.
Q3: Can Uniprim antibiotic powder be used in horses with liver disease or blood disorders?
Ans: No. Uniprim is contraindicated in horses with significant liver damage, blood dyscrasias, or a known sensitivity to sulfonamide medications. Horses on extended courses also need periodic blood monitoring to catch any early signs of suppressed blood cell production before it becomes a problem.
Q4: Is Uniprim trimethoprim sulfadiazine powder safe for foals?
Ans: Uniprim is well tolerated by foals at the recommended dose and no harmful effects on stallion spermatogenesis have been observed. Its safety during equine pregnancy has not been fully established, so pregnant mares should only receive it when a veterinarian has weighed the benefits and potential risks.
Q5: Is Uniprim Powder FDA-approved for use in horses?
Ans: Uniprim Powder carries full FDA approval as a prescription oral antibiotic for horses. It is manufactured in the USA and has been cleared for use in both horses and foals. Your veterinarian will need to provide a valid prescription before this product can be purchased.
Clinical Research
https://www.govinfo.gov/content/pkg/FR-1999-12-07/html/99-31571.htm