Uniprim for Horses Apple Flavor Powder

Apple-Flavored FDA-Approved Antibiotic Powder for Bacterial Infections in Horses

Product Description

Uniprim Apple Flavor (Trimethoprim and Sulfadiazine) Powder for Horses is an FDA-approved prescription antibiotic in a palatable apple-flavored powder, containing 67 mg trimethoprim and 333 mg sulfadiazine per gram — the same clinically proven 1:5 ratio as unflavored Uniprim. Designed to top-dress on feed once daily, the apple flavoring increases palatability for horses that resist unflavored powders. It provides the same potent systemic double-blockade antibacterial action and is indicated for the same four bacterial infection categories. Made in the USA and available in four jar and pail sizes plus single-dose packets.

Benefits

• Enhanced Palatability for Resistant Horses: Apple flavoring improves acceptance in horses that refuse or eat around unflavored antibiotic powders mixed into feed.
• Dual Sequential Antibacterial Blockade: Trimethoprim blocks dihydrofolate reductase while sulfadiazine inhibits dihydrofolic acid synthesis, targeting two steps in bacterial folic acid metabolism.
• Respiratory Tract Infection Treatment: Indicated for systemic antibacterial control of respiratory tract infections caused by susceptible organisms in horses and foals.
• Acute Strangles Treatment: Indicated for the control and treatment of acute strangles requiring potent systemic antibacterial action in horses.
• Wound and Abscess Treatment: Provides effective antibacterial coverage for wound infections and abscesses requiring systemic treatment in horses.
• Urogenital Infection Treatment: Indicated for acute urogenital infections requiring potent systemic antibacterial action against susceptible bacteria in horses.
• Safe for Foals and Stallions: Well tolerated by foals at the recommended dose; no detrimental effect on stallion spermatogenesis was observed at the recommended dosage.

Variants

Uniprim Apple Flavor 37.5 g

Uniprim Apple Flavor 200 g Jar

Uniprim Apple Flavor 400 g Jar

Uniprim Apple Flavor 1,200 g Jar

Uniprim Apple Flavor 2,000 g Bucket

Ingredients

Active Ingredients

Trimethoprim: 67 mg per gram | Sulfadiazine: 333 mg per gram (1:5 ratio)

Inactive Ingredients

Apple flavoring, carrier base

How to Use

Dosage and Administration Instructions

• Prescription Required: Federal (USA) law restricts Uniprim Apple Flavor Powder to use by or on the order of a licensed veterinarian only.
• Daily Dose: Each dose is based on your horse's body weight; one full packet or two level scoops covers a standard 1,100 lb horse for one day.
• Adjusted Dose Reference: A simple rule of thumb for on-farm use is roughly one teaspoon of powder per 100 lbs of your horse's body weight each day.
• Top-Dress on Feed: Stir the measured dose into a small portion of feed; the apple flavor helps most horses accept it without any fuss.
• Confirm Full Consumption: Make sure your horse finishes the medicated feed portion completely before offering any additional plain feed to avoid a partial dose.
• Keep Water Available: Fresh water should be within easy reach of your horse at all times during the course of treatment.
• Agitate Jar Before Scooping: Give the jar a gentle shake before measuring each dose, as the powder can settle between uses and throw off accuracy.
• Treatment Duration: The standard course runs once daily for 5 to 7 days; keep going for another 2 to 3 days after symptoms clear up to make sure the infection is fully resolved.
• Re-evaluate at 3-5 Days: If no clinical improvement is evident within 3-5 days for acute infections, re-evaluate the diagnosis before continuing therapy.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Contraindicated in Liver Disease: Do not use in horses with marked liver parenchymal damage; trimethoprim and sulfadiazine are not suitable in these animals.
• Contraindicated in Blood Dyscrasias: Do not administer to horses with blood dyscrasias; this combination antibiotic may further suppress hematopoietic activity.
• Sulfonamide Sensitivity: Do not use in horses with a known history of sulfonamide hypersensitivity; anaphylactoid reactions may be fatal.
• Periodic Blood Monitoring: For horses receiving prolonged treatment, periodic platelet, white blood cell, and red blood cell counts are advisable.
• Discontinue if Blood Count Drops: If significant reduction in any formed blood element is detected, discontinue Uniprim treatment immediately and consult your veterinarian.
• Pregnancy Not Evaluated: The effect of trimethoprim and sulfadiazine on equine pregnancy has not been determined; veterinary guidance is essential for use in pregnant mares.
• Not for Human Consumption: Do not use in horses intended for human food consumption.
• Secure Storage Required: Dogs, cats, and other household animals must never have access to this product, as accidental consumption can cause serious harm.

Possible Side Effects

• Anorexia: One case of anorexia was reported during clinical trials; monitor the horse's daily feed intake throughout the treatment period.
• Diarrhea: Post-approval reports confirm horses have developed diarrhea during trimethoprim and sulfadiazine treatment, which may be potentially fatal; monitor closely.
• Hypersensitivity Reactions: Individual hypersensitivity may result in local or generalized reactions, sometimes fatal; anaphylactoid reactions are rare but possible.
• Hematopoietic Suppression: High or prolonged dosing may cause slight to moderate reductions in hematopoietic activity; reversible with leucovorin or by stopping the drug.

Storage Information

• Room Temperature Storage: Store between 15-30°C (59-86°F) in a dry location away from excess moisture and direct sunlight to preserve powder quality.
• Keep Out of Reach: Store in a secure, locked location away from children, dogs, cats, and other animals at all times.

Shipping & Return

We offer ground, express, and priority delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What makes Uniprim Apple Flavor powder different from regular unflavored Uniprim?

Ans: Uniprim Apple Flavor contains 67 mg trimethoprim and 333 mg sulfadiazine per gram, matching the unflavored version in both indications and dosing. Horses that resist plain antibiotic powder in their feed tend to accept the apple-flavored version much more readily. This flavor also comes in a 1,200 g jar size that is only available in the apple flavor range.

Q2: What is the correct dose of Uniprim Apple Flavor for horses?

Ans: Administer 3.75 g per 110 lbs (50 kg) of body weight once daily. Two level loose-filled 32 cc scoops from any jar or pail equal one 37.5 g dose sufficient to treat a 1,100 lb horse. An easy field reference is 1 teaspoon per 100 lbs. Gently agitate the container before measuring as contents may settle.

Q3: Can Uniprim Apple Flavor horse antibiotic powder be used in foals?

Ans: Yes. Uniprim Powder for Horses is well tolerated by foals at the recommended dose. No detrimental effect on stallion spermatogenesis has been observed at the recommended dosage. The effect on equine pregnancy remains undetermined; consult your veterinarian before use in pregnant mares.

Q4: How many doses does each size of Uniprim Apple Flavor powder provide for an average horse?

Ans: For a 1,100 lb horse: the 200 g jar provides approximately 5 doses; the 400 g jar approximately 10 doses; the 1,200 g jar approximately 32 doses; and the 2,000 g pail approximately 53 doses. Single-dose 37.5 g packets provide exactly one dose each per horse per day.

Q5: What should I do if my horse develops diarrhea while on Uniprim Apple Flavor treatment?

Ans: Diarrhea is a known post-approval adverse event with trimethoprim-sulfadiazine treatment in horses and may potentially be fatal. If your horse develops diarrhea during treatment, contact your veterinarian immediately. Do not continue administering Uniprim without veterinary guidance, as discontinuation may be necessary.

Clinical Research

Uniprim Powder for Horses - Drugs.com