Advocin (danofloxacin mesylate) Sterile Injectable Solution 180mg/mL

Fast BRD Relief for Beef Cattle

Product Description

ADVOCIN is a sterile injectable antimicrobial solution specifically for the treatment and control of bovine respiratory disease in beef cattle. With a short four-day withdrawal time, it is ideal for use throughout the feeding period. ADVOCIN delivers fast lung penetration, helps animals recover from BRD, and supports better weight gain compared with untreated cattle.

Benefits

• Rapid Lung Action: Reaches peak lung concentration within one hour of administration.
• High Cure Rates: Field studies show better BRD cure rates than negative controls.
• Improved Weight Gain: Treated cattle achieved increased weight gain versus untreated controls.
• Convenient Use: Can be used any time in the feeding period with a four day withdrawal.
• Lower Volume Dose: Requires smaller injection volume compared to similar products. Manufacturer Info

Ingredients

Active Ingredients

Danofloxacin mesylate 180 mg per mL (providing 200 mg danofloxacin)

Variants

• 100 mL multi-dose vial
• 250 mL multi-dose via

How to Use

Recommended Dosage Chart

Dosage & Administration Instructions

• Approved Regimens: ADVOCIN is labeled for a single dose or two dose regimen for BRD.
• Labeled Dosage: The product is approved at 8 mg per kg once or 6 mg per kg twice.
• Injection Volume Limit: Labeled administration volume should not exceed 15 mL per injection site.
• Prescription Status: ADVOCIN is restricted to use by or on the order of a licensed veterinarian.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

• Reproductive Effects: Effects on bovine reproductive performance have not been fully determined.
• Cartilage Risk: Fluoroquinolones may cause cartilage changes in immature animals.
• Veal Restriction: Not approved for calves intended for processing as veal.

Possible Side Effects

• Injection Swelling: Transient swelling at the injection site has been reported in some cattle.
• Local Irritation: Mild localized tissue reactions may occur at the injection site.

Storage Information

• Temperature Limit: Store at or below 30°C or 86°F to maintain product stability.
• Light Protection: The product should be protected from light during storage.
• Puncture Use Window: Contents should be used within 28 days of first vial puncture.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is ADVOCIN used for in cattle?

Ans: ADVOCIN is FDA approved for the treatment and control of bovine respiratory disease in beef cattle. It specifically targets infections associated with Mannheimia haemolytica and Pasteurella multocida, two common BRD causing bacteria found in feedlot and high risk cattle populations.

Q2: How quickly does ADVOCIN start working after injection?

Ans: According to manufacturer data, ADVOCIN reaches peak lung concentrations within one hour of administration. This rapid distribution to lung tissue supports early antimicrobial activity at the primary site of respiratory infection in beef cattle diagnosed with bovine respiratory disease.

Q3: Can ADVOCIN be used late in the feeding period?

Ans: Yes, ADVOCIN is labeled for use at any point during the feeding period, including late stages. Its short four day meat withdrawal time makes it suitable for cattle nearing market readiness while remaining compliant with FDA residue requirements.

Q4: Is ADVOCIN approved for use in dairy cattle or veal calves?

Ans: No, ADVOCIN is not approved for use in dairy cattle or calves intended for veal production. FDA labeling restricts its use exclusively to beef cattle due to residue, safety, and regulatory considerations specific to milk and veal products.

Q5: Does ADVOCIN require a veterinary prescription?

Ans: Yes, ADVOCIN is a prescription only veterinary antimicrobial. FDA regulations require it to be used by or on the order of a licensed veterinarian to ensure appropriate diagnosis, responsible antimicrobial use, and compliance with animal health and food safety standards.