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BO-SE Injection (Selenium and Vitamin E) 1mg/mL, 100mL

$45.99

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Prescription Required

Merck Animal Health SKU: 065478-MER

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Selenium and Vitamin E Support for Livestock Health

Product Description

BO-SE® Injection is a selenium and vitamin E solution given by injection to help prevent and treat white muscle disease, along with other related nutrient deficiencies. It is used in calves, lambs, ewes, sows, and weanling pigs. This veterinary product is especially helpful in areas where animals are not getting enough selenium or vitamin E in their diet. When used under a veterinarian’s guidance, it supports healthy muscle function and overall well being.

Benefits

  • Muscle Protection: Helps maintain healthy muscle tissue in livestock prone to selenium or vitamin E deficiency.
  • Disease Prevention: Supports the prevention of white muscle disease in susceptible young animals.
  • Broad Species Use: Suitable for use in calves, lambs, ewes, sows, and weanling pigs under vet supervision.
  • Fast Absorption: Injectable form bypasses digestion for quicker nutrient availability.
  • Veterinarian Recommended: For use when dietary intake is insufficient, and an official diagnosis confirms deficiency.

Ingredients

Composition Table

Ingredient

Quantity per mL

Sodium selenite (equivalent to selenium)

1 mg

Vitamin E (d-alpha tocopheryl acetate)

50 mg (68 USP units)

Polysorbate 80

250 mg

Benzyl alcohol (preservative)

2%

Water for injection

q.s.

Other Ingredients

To reach the proper pH, sodium hydroxide or hydrochloric acid can be added during the process.

Guaranteed Analysis

Nutrient

Amount

Selenium

1 mg per mL

Vitamin E

50 mg (68 USP units) per mL

How to Use

Recommended-Dosage Chart

Species

Recommended Dosage

Route

Calves

2.5 to 3.75 mL per 100 lb body weight

Subcutaneous or Intramuscular

Lambs 2 weeks and older

1 mL per 40 lb body weight, minimum 1 mL

Subcutaneous or Intramuscular

Ewes

2.5 mL per 100 lb body weight

Subcutaneous or Intramuscular

Sows

1 mL per 40 lb body weight

Subcutaneous or Intramuscular

Weanling pigs

1 mL per 40 lb body weight, minimum 1 mL

Subcutaneous or Intramuscular

Dosage & Administration Instructions

  • Injection Route: Give the injection either under the skin or into the muscle, depending on the species and the recommended dosing guidelines.
  • Weight Based Dosing: Always calculate the dose based on the animal’s accurate body weight. Careful dosing is important to avoid the risk of selenium toxicity.
  • Pregnant Ewe Restriction: Do not use in pregnant ewes, as it may cause abortions or even death.
  • Slaughter Withdrawal: Observe 30 30-day withdrawal for calves and 14-day withdrawal for other listed species.
  • Veterinary Prescription: Federal law restricts use to licensed veterinarians or their direct order.

Disclaimer: This dosage information is provided by the manufacturer. Always consult your veterinarian before administering or adjusting any supplement for your pet.

Additional Information

Precautions

  • Accurate Diagnosis: Make sure a selenium deficiency is properly confirmed before starting treatment. Similar signs can show up with other health issues, so a clear diagnosis matters.
  • Monitor Levels: Blood tests such as serum selenium, SGOT, and creatine levels can help support the diagnosis and track the animal’s status.
  • Avoid Overdose: Selenium can be toxic if too much is given, so it’s important to follow the recommended dose and schedule carefully.
  • Check Product Quality: Before using the product, look at the solution closely. Do not use it if it appears cloudy or shows any separation.

Possible Side Effects

  • Anaphylactoid Reactions: Severe reactions, including excitement, sweating, trembling, and respiratory distress, may occur.
  • Cardiac Dysfunction: Cardiac complications and fatalities have been reported following administration.
  • Respiratory Distress: Acute respiratory difficulty, frothing, and bloating were reported, especially in pregnant ewes.
  • Abortions Reported: Abortions and deaths have occurred in pregnant ewes administered this product.

Storage Information

  • Controlled Temperature: Store at 25°C with permitted excursions between 23°C and 32°C.
  • Limited Punctures: Use within 90 days of first puncture and limit to 12 punctures maximum.
  • Discard After Large Needle Use: Discard remaining product if using a draw-off spike larger than 16G.
  • Inspect Before Use: Do not use if the product becomes turbid or separates into phases.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Prescription items are NON-RETURNABLE and NON-REFUNDABLE.

Frequently Asked Questions

Q1: What is BO-SE Injection used for in livestock?

Ans: BO-SE Injection is used for the prevention and treatment of white muscle disease, also known as Selenium-Tocopherol Deficiency, in calves, lambs, and ewes. It is also used in sows and weanling pigs to aid in preventing diseases associated with selenium and vitamin E deficiency.

Q2: Which animal species can receive BO-SE Injection?

Ans: BO-SE Injection is approved for use in calves, lambs two weeks of age and older, ewes, sows, and weanling pigs. It is not for use in newborn pigs and must not be administered to pregnant ewes due to reported adverse reactions.

Q3: How is BO-SE Injection administered?

Ans: BO-SE Injection is administered either subcutaneously or intramuscularly, depending on veterinary guidance. The dosage is calculated according to species and body weight. Careful adherence to labeled dosing instructions is required due to the potential toxicity of selenium.

Q4: Are there any withdrawal periods before slaughter?

Ans: Yes, treated calves must not be slaughtered for human consumption within 30 days of administration. For lambs, ewes, sows, and pigs, a 14-day withdrawal period is required before slaughter to comply with residue safety guidelines.

Q5: What side effects can occur with BO-SE Injection?

Ans: Reported side effects include anaphylactoid reactions such as excitement, sweating, trembling, respiratory distress, and cardiac dysfunction. Fatalities and abortions have been reported in pregnant ewes. Immediate veterinary attention is necessary if adverse reactions occur.